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CC BY-NC-ND 4.0 · Endosc Int Open 2025; 13: a24679140
DOI: 10.1055/a-2467-9140
Original article

Endoscopic features of solitary colorectal hamartomatous polyps: Solitary juvenile polyp and Peutz-Jeghers polyp

Keisuke Kawasaki 
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Takehiro Torisu
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Junji Umeno
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Koichi Kurahara
2   Division of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan (Ringgold ID: RIN37100)
,
Shinjiro Egashira
2   Division of Gastroenterology, Matsuyama Red Cross Hospital, Matsuyama, Japan (Ringgold ID: RIN37100)
,
Satoshi Miyazono
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Yoshiaki Taniguchi
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Yumi Oshiro
3   Department of Pathology, Matsuyama Red Cross Hospital, Matsuyama, Japan (Ringgold ID: RIN37100)
,
Shinichiro Kawatoko
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Tomohiro Nagasue
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Yuichi Matsuno
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Naonori Kawakubo
4   Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Kouji Nagata
4   Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Tomohiko Moriyama
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Tatsuro Tajiri
4   Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
,
Takanari Kitazono
1   Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (Ringgold ID: RIN12923)
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Abstract

Background and study aims

The aim of this study was to clarify the endoscopic characteristics of colorectal hamartomatous polyps, including solitary juvenile polyp (JP) and solitary Peutz-Jeghers polyp (PJP).

Patients and methods

We reviewed the clinicopathological and endoscopic findings of 151 colorectal polyps with a diagnosis of solitary JP or solitary PJP. The clinicopathological and endoscopic findings of 119 JPs and 32 PJPs were retrospectively compared.

Results

Endoscopic findings included significantly higher incidences of erosion, whitish exudates, and chicken-skin mucosa in JPs compared with PJPs. A lobular surface was more common in PJPs. Magnified narrow-band imaging endoscopic findings indicated that expanded crypt openings, sparse marginal crypt epithelia, and proliferation of capillary vessels were characteristic of JPs. Branching structures were more prevalent in PJPs. Magnifying chromoendoscopy found a predominance of star-like pit patterns and decreased pit densities in JPs, whereas tubular and branching pit patterns were more frequent in PJPs. Neither type of polyp was found to contain adenomas, dysplasia, or malignant cells. Combinations of specific characteristic endoscopic findings in the JPs and PJPs showed high diagnostic accuracy for those polyps.

Conclusions

Solitary JPs and PJPs in the colorectum manifested characteristic endoscopic findings, and combinations of specific characteristic endoscopic findings may be useful for endoscopic diagnosis of solitary JPs and PJPs.

Keywords

Endoscopy Lower GI Tract - Polyps / adenomas / ... - Diagnosis and imaging (inc chromoendoscopy, NBI, iSCAN, FICE, CLE...) - Tissue diagnosis


Publication History

Received: 28 May 2024

Accepted after revision: 13 November 2024

Accepted Manuscript online:
21 November 2024

Article published online:
13 January 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany

Bibliographical Record
Keisuke Kawasaki, Takehiro Torisu, Junji Umeno, Koichi Kurahara, Shinjiro Egashira, Satoshi Miyazono, Yoshiaki Taniguchi, Yumi Oshiro, Shinichiro Kawatoko, Tomohiro Nagasue, Yuichi Matsuno, Naonori Kawakubo, Kouji Nagata, Tomohiko Moriyama, Tatsuro Tajiri, Takanari Kitazono. Endoscopic features of solitary colorectal hamartomatous polyps: Solitary juvenile polyp and Peutz-Jeghers polyp. Endosc Int Open 2025; 13: a24679140.
DOI: 10.1055/a-2467-9140
 

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