Open Access
CC BY-NC-ND 4.0 · Endosc Int Open 2024; 12(10): E1160-E1161
DOI: 10.1055/a-2387-1845
VidEIO

Self-assembling peptide improves the efficacy and safety of endoscopic band ligation for colonic diverticular bleeding

Authors

  • Yuki Takeuchi

    1   Gastroenterology, Takagi Hospital, Okawa, Japan (Ringgold ID: RIN38053)
    2   Gastroenterology, Karatsu Red Cross Hospital, Karatsu, Japan (Ringgold ID: RIN36835)
  • Koichi Miyahara

    2   Gastroenterology, Karatsu Red Cross Hospital, Karatsu, Japan (Ringgold ID: RIN36835)
  • Daisuke Yamaguchi

    3   Endoscopy and Endoscopic Surgery, Saga University Hospital, Saga, Japan (Ringgold ID: RIN469771)
  • Moeko Shirozu

    4   Gastroenterology, Saga University Hospital, Saga, Japan (Ringgold ID: RIN469771)
  • Ryuma Morita

    5   Gastroenterology, Saga Prefecture Medical Center Koseikan, Saga, Japan (Ringgold ID: RIN38441)
  • Kenichiro Nakayama

    2   Gastroenterology, Karatsu Red Cross Hospital, Karatsu, Japan (Ringgold ID: RIN36835)
  • Takahiro Noda

    2   Gastroenterology, Karatsu Red Cross Hospital, Karatsu, Japan (Ringgold ID: RIN36835)
Preview

Introduction

Endoscopic band ligation (EBL) for colonic diverticular bleeding (CDB) is useful treatment, offering lower rebleeding rates, reduced need for interventional radiology, and shorter length of hospital stay, compared with clip therapy [1] [2] However, it requires some time to attach an EBL device after the bleeding source has been identified, which can cause problems with prolonged bleeding [1] [2] [3]. Furthermore, continuous bleeding can cause visibility to be impaired, and make it difficult to identify the bleeding source and potentially worsen the patient's condition.

Self-assembling peptide is indicated for hemostasis of oozing bleeding [4], but a case report exists of self-assembling peptide solution temporarily stopping spurting bleeding [5]. We considered that self-assembling peptide might help solve the problem.



Publikationsverlauf

Eingereicht: 07. Mai 2024

Angenommen nach Revision: 31. Juli 2024

Artikel online veröffentlicht:
15. Oktober 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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