Kardiologie up2date, Table of Contents Kardiologie up2date 2024; 20(03): 211-216DOI: 10.1055/a-2351-1977 Schritt für Schritt Vorhofohrverschluss – Schritt für Schritt Authors Kolja Sievert Stefan Bertog Horst Sievert Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Thromben im linken Vorhofohr infolge von Vorhofflimmern sind die häufigste Ursache embolischer Schlaganfälle [1]. Antikoagulanzien sind eine wirksame Prophylaxe [2]. Patienten mit nicht-valvulärem Vorhofflimmern mit Kontraindikationen gegen eine Antikoagulation können von einem Vorhofohrverschluss profitieren [3]. Full Text References Literatur 1 Michel P, Odier C, Faouzi M. et al. The Acute STroke Registry and Analysis of Lausanne (ASTRAL). Stroke 2010; 41: 2491-2498 2 Hart RG, Pearce LA, Aguilar MI. Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation. Ann Intern Med 2007; 146: 857-867 3 Holmes Jr DR, Doshi SK, Kar S. et al. Left Atrial Appendage Closure as an Alternative to Warfarin for Stroke Prevention in Atrial Fibrillation: A Patient-Level Meta-Analysis. J Am Coll Cardiol 2015; 65: 2614-2623 4 Glikson M, Wolff R, Hindricks G. et al. EHRA/EAPCI expert consensus statement on catheter-based left atrial appendage occlusion – an update. EuroIntervention 2020; 15: 1133-1180 5 Holmes DR, Reddy VY, Turi ZG. et al. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet 2009; 374: 534-542 6 Reddy VY, Gibson DN, Kar S. et al. Post-Approval U.S. Experience With Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation. J Am Coll Cardiol 2017; 69: 253-261 7 Boersma LVA, Schmidt B, Betts TR. et al. Implant success and safety of left atrial appendage closure with the WATCHMAN device: peri-procedural outcomes from the EWOLUTION registry. Eur Heart J 2016; 37: 2465-2474 8 Sondergaard L, Wong Y-H, Reddy VY. et al. Propensity-Matched Comparison of Oral Anticoagulation Versus Antiplatelet Therapy After Left Atrial Appendage Closure With Watchman. JACC Cardiovasc Interv 2019; 12: 1055-1063 9 Reddy VY, Doshi SK, Kar S. et al. 5-Year outcomes after left atrial appendage closure: From the PREVAIL and PROTECT AF Trials. J Am Coll Cardiol 2017; 70: 2964-2975 10 Osmancik O, Tousek P, Herman D. et al. Interventional left atrial appendage closure vs novel anticoagulation agents in patients with atrial fibrillation indicated for long-term anticoagulation (PRAGUE-17 study). Am Heart J 2017; 183: 108-114