Abstract
Endothelial dysfunctions together with a dysregulated immune response and lipid accumulation
are important confounding factors in the onset and chronic development of atherosclerosis.
Recently, a large body of data has emerged on the sequential involvement of different
immune cell types, including monocytes, in the pathology of this disease. In this
condensed review, we aim to highlight some of the recent basic research and clinical
findings on monocyte subsets published since our joint European Society of Cardiology
consensus document, and re-evaluate their potential relevance as surrogate biomarkers
in coronary artery disease.
Keywords
monocytes - atherosclerosis - leukocytes - activation
