Primary Mandibular Tuberculous Osteomyelitis Mimicking Ameloblastoma: A Case Report and Literature Review of Mandibular Tuberculous Osteomyelitis

Abstract

Primary tuberculous osteomyelitis involving the mandible represents less than 2% of skeletal locations. In this paper, we report a case of mandibular tuberculosis (TB) detected after histopathological analysis of the surgically resected specimen during surgical management of a suspected case of ameloblastoma. A 14-year-old male patient presented to us with history of right-sided chin swelling. The clinical examination revealed a swelling, involving right body and parasymphysis of mandible, measuring approximately 6 cm in length and 2 cm in width, extending from right lateral incisor till the first molar. Radiological scans revealed a large multiloculated osteolytic expansive lesion measuring 52 × 20 × 18 mm. Excision of the lesion was performed and reconstruction was done with iliac bone grafting. The histopathological findings revealed a granulomatous lesion, suggestive of tuberculous osteomyelitis. The patient was successfully treated with standard multidrug therapy. One year after completion of therapy, there were no signs of recurrence. Primary mandibular TB is an extremely rare entity. Its clinical presentation is not specific. Radiologically, TB has no characteristic appearance. The positive diagnosis is based on histology. Primary mandibular TB is rare and should be kept among differential diagnoses in susceptible population and in endemic areas.

Keywords

mandible - osteomyelitis - tuberculosis

Authors' Contributions

Conceptualization: C.C. and A.K. Methodology: C.C., A.K. and K.B. Writing - original draft: A.K., K.B. and R.M. Writing - review & editing: C.C., A.K., K.B. and R.M.

Ethical Approval

Ethics and IRB approval not available in the institute where the surgery was performed.

Patient Consent

Informed consent was taken from the patient and his father for publication.

Publikationsverlauf

Eingereicht: 02. April 2023

Angenommen: 08. November 2023

Accepted Manuscript online:
25. November 2023

Artikel online veröffentlicht:
29. Februar 2024

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