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DOI: 10.1055/a-2207-7587
Management of Ptosis in Kearns–Sayre Syndrome: A Case Report and Literature Review
Authors
Abstract
Kearns–Sayre syndrome (KSS) is a rare mitochondrial disease that affects young adults, due to a deletion of mitochondrial DNA and characterized by the triad: age of onset lower than 20 years, chronic progressive external ophthalmoplegia, and an atypical pigmentary retinopathy. It is also characterized by other endocrine, neurological, and especially cardiac impairment with a very high risk of cardiac complications during surgical procedures under all types of anesthesia.
We report a case of KSS revealed by severe bilateral ptosis and confirmed by a muscle biopsy with “ragged red fibers.” The ptosis was surgically managed by cautious Frontal suspension under local anesthesia “Frontal nerve block.” Through this case, we discuss challenges in the management of KSS patients.
Keywords
Kearns–Sayre syndrome - ptosis - chronic progressive external ophthalmoplegia - Frontal suspensionAuthors' Contributions
Conceptualization: M.O.M., Z.A. Data curation: M.O.M., Z. A. Writing - original draft: M.O.M., Z.A. Writing - review & editing: M.O.M., Z.A., F.M., B.O., N.H., K.M.
Ethical Approval
The study was approved by the Biomedical Research Ethics Committee of the Faculty of Medicine and Pharmacy of Casablanca (IRB no. 00002504).
Patient Consent
The patient and his family have given their explicit consent for their data and photos to be used for scientific purposes.
Publikationsverlauf
Eingereicht: 30. März 2023
Angenommen: 25. Oktober 2023
Accepted Manuscript online:
09. November 2023
Artikel online veröffentlicht:
08. April 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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