Subscribe to RSS
Download PDF
DOI: 10.1055/a-2192-5775
Proton Therapy for Skull Base Chondrosarcoma
Abstract
Chondrosarcoma is a type of an endochondral bone malignancy that is primarily treated surgically with radiation therapy used in the adjuvant setting or in cases of unresectable disease. Proton therapy has potential advantages compared with traditional photon therapy for the treatment of tumors in close proximity to critical structures due to the theoretic lower exit dose. Studies have shown improved survival in patients with skull base chondrosarcoma who undergo proton therapy. However, there is a lack of randomized data. Further studies are needed to define the role of proton therapy in the treatment of skull base chondrosarcoma.
Publication History
Received: 27 September 2023
Accepted: 06 October 2023
Accepted Manuscript online:
16 October 2023
Article published online:
20 November 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Noel G, Gondi V. Proton therapy for tumors of the base of the skull. Chin Clin Oncol 2016; 5 (04) 51
- 2 Amichetti M, Amelio D, Cianchetti M, Enrici RM, Minniti G. A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base. Neurosurg Rev 2010; 33 (02) 155-165
- 3 Simon F, Feuvret L, Bresson D. et al. Surgery and proton therapy in Grade I and II skull base chondrosarcoma: a comparative retrospective study. PLoS One 2018; 13 (12) e0208786
- 4 Hasegawa H, Vakharia K, Graffeo CS. et al. Long-term outcomes of grade I/II skull base chondrosarcoma: an insight into the role of surgery and upfront radiotherapy. J Neurooncol 2021; 153 (02) 273-281
- 5 Palmisciano P, Haider AS, Sabahi M. et al. Primary skull base chondrosarcomas: a systematic review. Cancers (Basel) 2021; 13 (23) 5960
- 6 Crockard HA, Cheeseman A, Steel T. et al. A multidisciplinary team approach to skull base chondrosarcomas. J Neurosurg 2001; 95 (02) 184-189
- 7 Bohman LE, Koch M, Bailey RL, Alonso-Basanta M, Lee JY. Skull base chordoma and chondrosarcoma: influence of clinical and demographic factors on prognosis: a SEER analysis. World Neurosurg 2014; 82 (05) 806-814
- 8 Chow WA. Update on chondrosarcomas. Curr Opin Oncol 2007; 19 (04) 371-376
- 9 Gelderblom H, Hogendoorn PC, Dijkstra SD. et al. The clinical approach towards chondrosarcoma. Oncologist 2008; 13 (03) 320-329 Erratum in: Oncologist. 2008 May;13(5):618. PMID: 18378543
- 10 Nguyen QN, Chang EL. Emerging role of proton beam radiation therapy for chordoma and chondrosarcoma of the skull base. Curr Oncol Rep 2008; 10 (04) 338-343
- 11 St Clair WH, Adams JA, Bues M. et al. Advantage of protons compared to conventional X-ray or IMRT in the treatment of a pediatric patient with medulloblastoma. Int J Radiat Oncol Biol Phys 2004; 58 (03) 727-734
- 12 Dabaja BS, Hoppe BS, Plastaras JP. et al. Proton therapy for adults with mediastinal lymphomas: the International Lymphoma Radiation Oncology Group guidelines. Blood 2018; 132 (16) 1635-1646
- 13 MacDonald SM, Trofimov A, Safai S. et al. Proton radiotherapy for pediatric central nervous system germ cell tumors: early clinical outcomes. Int J Radiat Oncol Biol Phys 2011; 79 (01) 121-129
- 14 Rosenberg AE, Nielsen GP, Keel SB. et al. Chondrosarcoma of the base of the skull: a clinicopathologic study of 200 cases with emphasis on its distinction from chordoma. Am J Surg Pathol 1999; 23 (11) 1370-1378
- 15 Hug EB, Loredo LN, Slater JD. et al. Proton radiation therapy for chordomas and chondrosarcomas of the skull base. J Neurosurg 1999; 91 (03) 432-439
- 16 Weber DC, Badiyan S, Malyapa R. et al. Long-term outcomes and prognostic factors of skull-base chondrosarcoma patients treated with pencil-beam scanning proton therapy at the Paul Scherrer Institute. Neuro-oncol 2016; 18 (02) 236-243
- 17 Feuvret L, Bracci S, Calugaru V. et al. Efficacy and safety of adjuvant proton therapy combined with surgery for chondrosarcoma of the skull base: a retrospective, population-based study. Int J Radiat Oncol Biol Phys 2016; 95 (01) 312-321
- 18 Rimmer RA, Mace JC, Andersen PE. et al. Determinants of survival in sinonasal and skull base chondrosarcoma: an analysis of the National Cancer Database. Int Forum Allergy Rhinol 2022; 12 (05) 699-713
- 19 Patel SH, Wang Z, Wong WW. et al. Charged particle therapy versus photon therapy for paranasal sinus and nasal cavity malignant diseases: a systematic review and meta-analysis. Lancet Oncol 2014; 15 (09) 1027-1038
- 20 Li PC, Liebsch NJ, Niemierko A. et al. Radiation tolerance of the optic pathway in patients treated with proton and photon radiotherapy. Radiother Oncol 2019; 131: 112-119
- 21 De Leo AN, Holtzman AL, Ho MW. et al. Vision loss following high-dose proton-based radiotherapy for skull-base chordoma and chondrosarcoma. Radiother Oncol 2021; 158: 125-130