Ultraschall Med 2024; 45(02): 199
DOI: 10.1055/a-2150-8253
Letter to the Editor

How to deal with an abnormal NIPT result?

Article in several languages: English | deutsch
Karl-Oliver Kagan
1   Obstetrics and gynaecology, University Hospital Tuebingen, Tuebingen, Germany
Renate Rosenberg
2   Practice for prenatal medicine, Münster, Germany
› Author Affiliations

Cell-free DNA analysis of maternal blood (cfDNA test or NIPT) is a screening test with high test performance regarding screening for trisomy 21, 18 and 13. Nevertheless, the plausibility of each result should be critically reviewed. This applies in particular to abnormal findings. The DEGUM has developed a recommendation for this situation to support attending physicians.

The following five aspects should be considered when dealing with an abnormal NIPT result:

Publication History

Received: 05 August 2023

Accepted: 08 August 2023

Accepted Manuscript online:
08 August 2023

Article published online:
08 February 2024

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