Thymom-assoziierte exfoliative Dermatitis

Die Thymom-assoziierte exfoliative Dermatitis ist eine seltene paraneoplastische Dermatose bei der Katze, deren Pathogenese bisher noch unklar ist. Nach Thymektomie kommt es bei den bisher beschriebenen Fällen meist zu einer vollständigen Ausheilung und Genesung der Patienten.

• Literatur

• 1 Smits B, Reid MM. Feline paraneoplastic syndrome associated with thymoma. N Z Vet J 2003; 51 (05) 244-247
• 2 Rottenberg S, Von Tscharner C, Roosje PJ. Thymoma-associated exfoliative dermatitis in cats. Vet Pathol 2004; 41 (04) 429-433
• 3 Day MJ. Review of thymic pathology in 30 cats and 36 dogs. J Small Anim Pract 1997; 38 (09) 393-403
• 4 Foley P, Shaw D, Runyon C. et al. Serum parathyroid hormone-related protein concentration in a dog with a thymoma and persistent hypercalcemia. Can Vet J 2000; 41 (11) 867-870
• 5 Robat CS, Cesario L, Gaeta R. et al. Clinical features, treatment options, and outcome in dogs with thymoma: 116 cases (1999–2010). J Am Vet Med Assoc 2013; 243 (10) 1448-1454
• 6 Dörfelt S, Fischer A, Meyer-Lindenberg A, Dörfelt R. Feline acquired thymoma-associated myasthenia gravis managed with surgery and therapeutic plasma exchange. Vet Rec Case Reports 2021; 9 (04) e211
• 7 Stephen JW, David MV. Withrow & MacEwenʼs small animal clinical oncology. 4th ed. St. Louis: Saunders Elsevier; 2007
• 8 Linek M, Rüfenacht S, Brachelente C. et al. Nonthymoma-associated exfoliative dermatitis in 18 cats. Vet Dermatol 2015; 26 (01) 40-e13
• 9 Possebom J, Rodrigues De Farias M, Liege De Assunção D, Werner J. Sebaceous Adenitis in a Cat. Acta Sci Vet 2015; 43: 1-5
• 10 Scott DW, Miller WH, Griffin CE. Small Animal Dermatology. 6th ed. Philadelphia: WB Saunders Co; 2001
• 11 Gross TL, Clark EG, Hargis AM. et al. Giant Cell Dermatosis in FeLV-positive Cats. Vet. Dermatol 1993; 4 (03) 117-122
• 12 Fontaine J, Heimann M, Day MJ. Cutaneous epitheliotropic T-cell lymphoma in the cat: a review of the literature and five new cases. Vet Dermatol 2011; 22 (05) 454-461
• 13 Vitale C, Ihrke P, Gross TL, Werner L. Systemic lupus erythematosus in a cat: fulfillment of the American Rheumatism Association criteria with supportive skin histopathology. Vet Dermatol 1997; 8 (02) 133-138
• 14 Gross T, Ihrke P, Walder E, Affolter V. Skin diseases of the dog and cat: clinical and histopathologic diagnosis. Iowa: Blackwell Science; 2008
• 15 Aronsohn M. Canine thymoma. Vet Clin North Am Small Anim Pract 1985; 15 (04) 775-777
• 16 Patterson MME, Marolf AJ. Sonographic characteristics of thymoma compared with mediastinal lymphoma. J Am Anim Hosp Assoc 2014; 50 (06) 409-413
• 17 Konde LJ, Spaulding K. Sonographic Evaluation Of The Cranial Mediastinum In Small Animals. Vet Radiol 1991; 32 (04) 178-184
• 18 Pintore L, Bertazzolo W, Bonfanti U. et al. Cytological and histological correlation in diagnosing feline and canine mediastinal masses. J Small Anim Pract 2014; 55 (01) 28-32
• 19 Raskin RE, Meyer D, Boes KM. Canine and Feline Cytopathology – E-book: A Color Atlas and Interpretation Guide. 4th ed. St. Louis: Elsevier Health Sciences; 2021
• 20 Day MJ. Diseases of lymphoid tissue. In: Day MJ. ed. Clinical Immunology of the Dog and Cat. 02. London: Manson Publishing; 2012: 369-390
• 21 Koga K, Matsuno Y, Noguchi M. et al. A review of 79 thymomas: Modification of staging system and reappraisal of conventional division into invasive and non-invasive thymoma. Pathol Int 2008; 44 (05) 359-367
• 22 Masaoka A, Monden Y, Nakahara K, Tanioka T. Follow-up study of thymomas with special reference to their clinical stages. Cancer 1981; 48 (11) 2485-2492
• 23 Yamakawa Y, Masaoka A, Hashimoto T. et al. A tentative tumor–node–metastasis classification of thymoma. Cancer 1991; 68 (09) 1984-1987
• 24 Burrow R. Thymectomy. In: Griffon D, Hamaide A. eds. Complications in Small Animal Surgery. Chichester: John Wiley & Sons Ltd; 2007: 328-334
• 25 Cavalcanti JVJ, Moura MP, Monteiro FO. Thymoma associated with exfoliative dermatitis in a cat. J Feline Med Surg 2014; 16 (12) 1020-1023
• 26 Mitcham SA, Clark EG, Mills JH. Malignant thymoma with widespread metastases in a dog: case report and brief literature review. Can Vet J 1984; 25 (07) 280
• 27 Moffet AC. Metastatic thymoma and acquired generalized myasthenia gravis in a beagle. Can Vet J 2007; 48 (01) 91-93
• 28 Patnaik AK, Lieberman PH, Erlandson RA, Antonescu C. Feline cystic thymoma: A clinicopathologic, immunohistologic, and electron microscopic study of 14 cases. J Feline Med Surg 2003; 5 (01) 27-35
• 29 Hljjfte MA, Forster-van Curtis CF, White RN. Resolution of exfoliative dermatitis and Malassezia pachydermatis overgrowth in a cat after surgical thymoma resection. J Small Anim Pract 1997; 38 (10) 451-454
• 30 Yale AD, Priestnall SL, Pittaway R, Taylor AJ. Thymic epithelial tumours in 51 dogs: Histopathologic and clinicopathologic findings. Vet Comp Oncol 2022; 20 (01) 50-58