Abstract
Neurodegeneration is characterized as the continuous functional and structural
loss of neurons, resulting in various clinical and pathological manifestations
and loss of functional anatomy. Medicinal plants have been oppressed from
ancient years and are highly considered throughout the world as a rich source of
therapeutic means for the prevention, treatment of various ailments.
Plant-derived medicinal products are becoming popular in India and other
nations. Further herbal therapies shows good impact on chronic long term
illnesses including degenerative conditions of neurons and brain. The use of
herbal medicines continues to expand rapidly across the world. The active
phytochemical constituents of individual plants are sometimes insufficient to
achieve the desirable therapeutic effects. Combining the multiple herbs in a
particular ratio (polyherbalism) will give a better therapeutic effect and
reduce toxicity. Herbal-based nanosystems are also being studied as a way to
enhance the delivery and bioavailability of phytochemical compounds for the
treatment of neurodegenerative diseases. This review mainly focuses on the
importance of the herbal medicines, polyherbalism and herbal-based nanosystems
and its clinical significance for neurodegenerative diseases.
Key words
herbal - neurodegeneration - extract - nanoformulation
