Zusammenfassung
Ziel Erfassung von Differenzialdiagnosen (DD) und Komorbiditäten
bei Erwachsenen mit Autismusverdacht, Überprüfung des Autismus
Quotient (AQ) auf seine Eignung für das Screening.
Methode Stichprobe N=106; ROC-Analyse des AQ gegen das klinische
Expertenurteil.
Ergebnisse Komorbide affektive Störungen in beiden Gruppen
(48%), DD waren Angst- (33%) und
Persönlichkeitsstörungen (22%). AQ: AUC=0,527,
Sensitivität/Spezifität von
70%/35%.
Schlussfolgerungen Erwachsene mit Autismusverdacht sind durch DD und
Komorbiditäten hoch belastet. Der AQ ist für das Screening nicht
geeignet.
Abstract
Autism spectrum disorders (ASD) often remain undiagnosed until adulthood.
The aim of this study is to report differential diagnoses (DDX) and
comorbidities of adults without intellectual impairment suspected of having an
ASD and to test the self-assessment questionnaire Autism Quotient (AQ) for its
suitability for screening.
Methods DDX and comorbidities were recorded with standardized scales in an
autism outpatient clinic in 106 individuals. The AQ was tested against the
expert judgment of an interdisciplinary case conference using ROC analysis.
Results Affective disorders were common in both groups (48%);
other DDX were phobias (33%) and personality disorders (22%).
The AQ showed an AUC of 0,527 with sensitivity/specificity of
70%/35%.
Conclusions Adults suspected of having autism are highly burdened by DDX
and comorbidities. An interdisciplinary diagnostic procedure based on
standardized scales is useful, whereas the AQ hardly differentiates between
persons with and without ASD.
Schlüsselwörter
Autismus-Spektrum Störung - Diagnostik - Erwachsene - Autismus Quotient (AQ) - Komorbiditäten
Key words
Autism spectrum condition - diagnostics - adults - Autism Quotient (AQ) - comorbidities
