CC BY-NC-ND 4.0 · Endosc Int Open 2023; 11(03): E284-E287
DOI: 10.1055/a-2032-4147
Original article

Newly designed OTS Clip for preventing fully-covered self-expandable metal stent migration in the gastrointestinal tract

Raffaele Manta
1   Gastroenterology and Digestive Endoscopy Unit, Santa Maria della Misericordia Hospital, Perugia, Italy
Lorenzo Del Nero
2   Gastroenterology Department, Santa Corona Hospital, Pietra Ligure (SV), Italy
Baron Todd
3   Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, United States
Andrea Parodi
4   Gastroenterology and Digestive Endoscopy Unit, Lavagna Hospital, Lavagna (GE), Italy
Antonella De Ceglie
5   Gastroenterology Department, General Hospital of Sanremo, Sanremo (IM), Italy
Francesco Zito
6   Gastroenterology and Digestive Endoscopy Unit, AORN “Antonio Cardarelli”, Napoli Italy
Luigi Pasquale
7   Gastroenterology Unit, S. O. Frangipane Hospital of A. Irpino, A. Irpino (AV), Italy
Angelo Zullo
8   Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita’ Hospital, Rome, Italy
Massimo Conio
5   Gastroenterology Department, General Hospital of Sanremo, Sanremo (IM), Italy
› Author Affiliations


Background and study aims Fully-covered self-expandable metal stents (FCSEMS) are frequently used for endoscopic management of gastrointestinal lesions. However, stent migration occurs in up to one-third of patients. Different tools are used to anchor stents to prevent migration. A specifically designed over-the-scope device (Stentfix OTS Clip system) was recently introduced to prevent fully covered SEMS migration in the gastrointestinal tract. The study aimed to evaluate technical success and stent migration rates with the Stentfix device.

Patients and methods Data were collected from consecutive patients at four participating centers who were at high risk of FCSEMS migration and in whom the anchoring system was used to prevent migration.

Results A total of 31 patients were enrolled. Technically successful clip placement was achieved in all cases. At follow-up, the distal part of the device dislocated from the duodenum into the antrum at 3 days in one patient, accounting for a 3.2 % (95 % CI = 0–9.4) rate of stent migration. The underlying lesion being treated healed in all patients, but 10 patients died before stent removal due to neoplastic progression.

Conclusions A dedicated over-the-scope stent fixation device appears to be safe and effective in preventing fully-covered SEMS migration through the gastrointestinal tract.

Publication History

Received: 30 May 2022

Accepted after revision: 11 October 2022

Article published online:
24 March 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

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