Executive Function Assessment in 2-Year-Olds Born Preterm

Abstract

Objective Our objective was to investigate the executive function and its relationship with gestational age, sex, maternal education, and neurodevelopmental outcome at 2 years corrected age in children born preterm.

Method Executive function was assessed by means of the Multisearch Multilocation Task (MSML), Reversed Categorization Task (RevCat), and Snack Delay Task (SDT). Infant and maternal characteristics were gathered from the child's record. The developmental outcome was measured by the Bayley Scales and a multidisciplinary risk evaluation for autism.

Results The executive function battery was completed by 97 children. The majority were able to successfully complete the MSML and SDT but failed RevCat. The lower the gestational age and the maternal education, the lower the executive function scores. Better cognition and motor function, as well as low autism risk, were associated with better executive function scores. Executive function was not related to sex.

Interpretation This cohort study provides evidence that it is feasible to assess executive function in 2-year-olds born preterm. Executive function is related to gestational age and maternal education and is positively correlated with behavioral outcome. Therefore, executive functions can be a valuable target for early intervention, resulting in improvements in neurodevelopmental outcomes in children born preterm.

Keywords

executive function - children born preterm - neurodevelopment

Clinical Trial Registration

Full name AND URL of the registry: ClinicalTrials.gov (http://www.clinicaltrials.gov/).

Registration number of your study: NCT02623400.

Type of study: Prospective.

Publication History

Received: 15 March 2022

Accepted: 07 January 2023

Accepted Manuscript online:
31 January 2023

Article published online:
07 March 2023

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