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DOI: 10.1055/a-1996-0157
F18-FDG PET/CT in a patient with Antisynthetase Syndrome
F18-FDG-PET/CT bei einem Patienten mit Antisynthetase-Syndrom
Abstract
More prevalent in women than men, Antisynthetase Syndrome is a rare and poorly defined autoimmune disease associated with interstitial lung disease, polymyositis, and dermatomyositis. In addition to various diagnostic tools, imaging modalities are needed in certain situations. A 42-year-old woman with Anti-Jo-1-positive Antisynthetase Syndrome presented with thoracic muscular pain. She underwent whole-body Fluorodeoxyglucose positron emission tomography/computed tomography (F18-FDG PET/CT) to evaluate the total extent of the muscles affected. Depicting symptomatic symmetric myositis of the intercostal muscles, F18-FDG PET/CT additionally revealed unusually extensive fasciitis of the lower extremities.
Publication History
Received: 07 November 2022
Accepted: 08 November 2022
Article published online:
04 January 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
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References
- 1 Fukamatsu H, Hirai Y, Miyake T. et al. Clinical manifestations of skin, lung and muscle diseases in dermatomyositis positive for anti-aminoacyl tRNA synthetase antibodies. J Dermatol 2019; 46: 886-897
- 2 Matuszak J, Blondet C, Hubelé F. et al. Muscle fluorodeoxyglucose uptake assessed by positron emission tomography–computed tomography as a biomarker of inflammatory myopathies disease activity. Rheumatology 2019; 58: 1459-1464
- 3 Bains S, Reimert M, Win AZ. et al. A Patient with Psoriatic Arthritis Imaged with FDG-PET/CT Demonstrated an Unusual Imaging Pattern with Muscle and Fascia Involvement: A Case Report. Nucl Med Mol Imaging 2012; 46: 138-143
- 4 Jain TK, Basher RK, Bhattacharya A. et al. 18F-FDG PET/CT in diagnosis and response evaluation in an unusual case of antisynthetase syndrome presenting as pyrexia of unknown origin. Rev Esp Med Nucl Imagen Mol 2016; 35: 197-199
- 5 Ebbo M, Chagnaud C, Figarella-Branger D. et al. Antisynthethase syndrome presenting as peripheral limb fasciitis. Joint Bone Spine 2013; 80: 528-530
- 6 Clarencon F, Larousserie F, Babinet A. et al. FDG PET/CT findings in a case of myositis ossificans circumscripta of the forearm. Clin Nucl Med 2011; 36: 40-42
- 7 Hotta M, Minamimoto R, Kaneko H. et al. Fluorodeoxyglucose PET/CT of Arthritis in Rheumatic Diseases: A Pictorial Review. RadioGraphics 2020; 40: 223-240
- 8 Kubota K, Yamashita H, Mimori A. Clinical Value of FDG-PET/CT for the Evaluation of Rheumatic Diseases: Rheumatoid Arthritis, Polymyalgia Rheumatica, and Relapsing Polychondritis. Seminars in Nuclear Medicine 2017; 47: 408-424