Subscribe to RSS
DOI: 10.1055/a-1978-5868
Prähabilitation als OP-Vorbereitung bei Patienten mit Frailty
Ältere Menschen, die sich operieren lassen müssen, sind besonders gefährdet, von diesem Eingriff nicht zu profitieren. Komplikationen während und nach der Operation, längere Liegezeiten und eine damit einhergehende eingeschränkte Rehabilitationsfähigkeit führen zu einem Verlust an Selbstständigkeit und Lebensqualität. Eine Prähabilitation vor der Operation kann diesem Verlauf entgegenwirken.
Abstract
Older people demonstrate a higher risk for the occurrence of peri- and postsurgical complications. A frequent risk factor for this is the prevalence of a status called “frailty”. In general, this status can be reversed by adequate therapeutic and medical interventions. More, current evidence suggests that these measures, as part of a so-called prehabilitation, can reduce the risk for experiencing peri- and postsurgical complications and thus assist the rehabilitation process, increase quality of life, and avoid care dependency and a loss of autonomy of these patients. In this article, we describe the concept of prehabilitation, its options to adapt and design this new form of intervention, as well as presenting current evidence. An actual project and a case example on prehabilitation provide an example and outlook.
-
Gebrechlichkeit (Frailty) ist ein komplexes Syndrom, charakterisiert durch die Verminderung physiologischer Reserven.
-
Die Prävalenz der Gebrechlichkeit bei älteren Menschen liegt bei bis zu 43%.
-
Mit einer Gebrechlichkeit gehen ein erhöhtes Risiko für peri- und postoperative Komplikationen einher und damit die Gefahr, dass die betroffenen Patienten von der Operation nicht profitieren.
-
Eine Gebrechlichkeit ist kein fixer Zustand und kann durch geeignete Maßnahmen positiv beeinflusst werden.
-
Eine Prähabilitation stellt eine präoperative Maßnahme zur Reduktion von peri- und postoperativen Komplikationen bei Risikogruppen dar.
-
Eine Prähabilitation sollte multiprofessionell und multimodal organisiert sein.
-
Weitere Forschung zur Evidenz der Effektivität einer Prähabilitation bei gebrechlichen älteren Menschen ist notwendig. In Deutschland erfolgt eine Evaluierung aktuell im Rahmen des Versorgungsforschungs-Projekts PRÄP-GO.
Publication History
Article published online:
02 February 2023
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Statista. Anzahl der Operationen vollstationärer Patienten in deutschen Krankenhäusern nach Altersgruppe im Jahr 2020. Accessed October 07, 2022 at: https://de.statista.com/statistik/daten/studie/29220/umfrage/krankenhaeuser-operationen-vollstationaerer-patienten/
- 2 Martin ET, Kaye KS, Knott C. et al. Diabetes and Risk of Surgical Site Infection: A Systematic Review and Meta-analysis. Infect Control Hosp Epidemiol 2016; 37: 88-99 DOI: 10.1017/ice.2015.249. (PMID: 26503187)
- 3 Smilowitz NR, Gupta N, Guo Y. et al. Trends in cardiovascular risk factor and disease prevalence in patients undergoing non-cardiac surgery. Heart 2018; 104: 1180-1186 DOI: 10.1136/heartjnl-2017-312391. (PMID: 29305561)
- 4 Smith TO, Cooper A, Peryer G. et al. Factors predicting incidence of post-operative delirium in older people following hip fracture surgery: a systematic review and meta-analysis. Int J Geriatr Psychiatry 2017; 32: 386-396 DOI: 10.1002/gps.4655. (PMID: 28093812)
- 5 Watt J, Tricco AC, Talbot-Hamon C. et al. Identifying older adults at risk of harm following elective surgery: a systematic review and meta-analysis. BMC Med 2018; 16: 2 DOI: 10.1186/s12916-017-0986-2. (PMID: 29325567)
- 6 Birkelbach O, Mörgeli R, Spies C. et al. Routine frailty assessment predicts postoperative complications in elderly patients across surgical disciplines – a retrospective observational study. BMC Anesthesiol 2019; 19: 204 DOI: 10.1186/s12871-019-0880-x. (PMID: 31699033)
- 7 Smilowitz NR, Berger JS. Perioperative Cardiovascular Risk Assessment and Management for Noncardiac Surgery: A Review. JAMA 2020; 324: 279-290 DOI: 10.1001/jama.2020.7840. (PMID: 32692391)
- 8 Jin Z, Hu J, Ma D. Postoperative delirium: perioperative assessment, risk reduction, and management. Br J Anaesth 2020; 125: 492-504 DOI: 10.1016/j.bja.2020.06.063. (PMID: 32798069)
- 9 Susano MJ, Grasfield RH, Friese M. et al. Brief Preoperative Screening for Frailty and Cognitive Impairment Predicts Delirium after Spine Surgery. Anesthesiology 2020; 133: 1184-1191 DOI: 10.1097/ALN.0000000000003523. (PMID: 32898243)
- 10 Sioutas G, Tsoulfas G. Frailty assessment and postoperative outcomes among patients undergoing general surgery. Surgeon 2020; 18: e55-e66 DOI: 10.1016/j.surge.2020.04.004. (PMID: 32417038)
- 11 Chan V, Wilson JRF, Ravinsky R. et al. Frailty adversely affects outcomes of patients undergoing spine surgery: a systematic review. Spine J 2021; 21: 988-1000 DOI: 10.1016/j.spinee.2021.01.028. (PMID: 33548521)
- 12 Fried LP, Tangen CM, Walston J. et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56: M146-M156 DOI: 10.1093/gerona/56.3.m146. (PMID: 11253156)
- 13 Drewniok N, Mörgeli R, Eckardt-Felmberg R. Frailty-Diagnostik in verschiedenen Settings. Anasthesiol Intensivmed Notfallmed Schmerzther 2022; 57: 682-696 DOI: 10.1055/a-1760-8228.
- 14 Veronese N, Custodero C, Cella A. et al. Prevalence of multidimensional frailty and pre-frailty in older people in different settings: A systematic review and meta-analysis. Ageing Res Rev 2021; 72: 101498 DOI: 10.1016/j.arr.2021.101498. (PMID: 34700009)
- 15 Collard RM, Boter H, Schoevers RA. et al. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc 2012; 60: 1487-1492 DOI: 10.1111/j.1532-5415.2012.04054.x. (PMID: 22881367)
- 16 Kojima G, Iliffe S, Walters K. Frailty index as a predictor of mortality: a systematic review and meta-analysis. Age Ageing 2018; 47: 193-200 DOI: 10.1093/ageing/afx162. (PMID: 29040347)
- 17 Gordon EH, Peel NM, Samanta M. et al. Sex differences in frailty: A systematic review and meta-analysis. Exp Gerontol 2017; 89: 30-40 DOI: 10.1016/j.exger.2016.12.021. (PMID: 28043934)
- 18 Kojima G. Frailty as a Predictor of Future Falls Among Community-Dwelling Older People: A Systematic Review and Meta-Analysis. J Am Med Dir Assoc 2015; 16: 1027-1033 DOI: 10.1016/j.jamda.2015.06.018. (PMID: 26255098)
- 19 Vermeiren S, Vella-Azzopardi R, Beckwée D. et al. Frailty and the Prediction of Negative Health Outcomes: A Meta-Analysis. J Am Med Dir Assoc 2016; 17: 1163.e1-1163.e17 DOI: 10.1016/j.jamda.2016.09.010. (PMID: 27886869)
- 20 Coventry PA, McMillan D, Clegg A. et al. Frailty and depression predict instrumental activities of daily living in older adults: A population-based longitudinal study using the CARE75+ cohort. PLoS One 2020; 15: e0243972 DOI: 10.1371/journal.pone.0243972. (PMID: 33320913)
- 21 Lin HS, Watts JN, Peel NM. et al. Frailty and post-operative outcomes in older surgical patients: a systematic review. BMC Geriatr 2016; 16: 157 DOI: 10.1186/s12877-016-0329-8. (PMID: 27580947)
- 22 George EL, Hall DE, Youk A. et al. Association Between Patient Frailty and Postoperative Mortality Across Multiple Noncardiac Surgical Specialties. JAMA Surg 2021; 156: e205152 DOI: 10.1001/jamasurg.2020.5152. (PMID: 33206156)
- 23 Lorenzo-López L, López-López R, Maseda A. et al. Changes in frailty status in a community-dwelling cohort of older adults: The VERISAÚDE study. Maturitas 2019; 119: 54-60 DOI: 10.1016/j.maturitas.2018.11.006. (PMID: 30502751)
- 24 Chiu HL, Yeh TT, Lo YT. et al. The effects of the Otago Exercise Programme on actual and perceived balance in older adults: A meta-analysis. PLoS One 2021; 16: e0255780 DOI: 10.1371/journal.pone.0255780. (PMID: 34358276)
- 25 Gurlit S, Gogol M. Prehabilitation is better than cure. Curr Opin Anaesthesiol 2019; 32: 108-115 DOI: 10.1097/ACO.0000000000000678. (PMID: 30507681)
- 26 Elsawy B, Higgins KE. Physical Activity Guidelines for Older Adults. Am Fam Physician 2010; 81: 55-59 (PMID: 20052963)
- 27 Bundeszentrale für gesundheitliche Aufklärung (BZgA). Nationale Empfehlungen für Bewegung und Bewegungsförderung. Sonderheft 3. Köln: 2016. 92.
- 28 Bammann K, Recke C, Albrecht BM. et al. Promoting Physical Activity Among Older Adults Using Community-Based Participatory Research With an Adapted PRECEDE-PROCEED Model Approach: The AEQUIPA/OUTDOOR ACTIVE Project. Am J Health Promot 2021; 35: 409-420 DOI: 10.1177/0890117120974876. (PMID: 33267636)
- 29 Dent E, Morley JE, Cruz-Jentoft AJ. et al. Physical Frailty: ICFSR International Clinical Practice Guidelines for Identification and Management. J Nutr Health Aging 2019; 23: 771-787 DOI: 10.1007/s12603-019-1273-z. (PMID: 31641726)
- 30 Baimas-George M, Watson M, Elhage S. et al. Prehabilitation in Frail Surgical Patients: A Systematic Review. World J Surg 2020; 44: 3668-3678 DOI: 10.1007/s00268-020-05658-0. (PMID: 32656590)
- 31 Carli F, Bousquet-Dion G, Awasthi R. et al. Effect of Multimodal Prehabilitation vs Postoperative Rehabilitation on 30-Day Postoperative Complications for Frail Patients Undergoing Resection of Colorectal Cancer: A Randomized Clinical Trial. JAMA Surg 2020; 155: 233-242 DOI: 10.1001/jamasurg.2019.5474. (PMID: 31968063)
- 32 PRÄP-GO. Forschungsprojekt. Vorbereitung auf Ihre OP für ein besseres Ergebnis. Accessed October 07, 2022 at: https://praep-go.de/
- 33 Volkert D, Beck AM, Cederholm T. et al. ESPEN guideline on clinical nutrition and hydration in geriatrics. Clin Nutr 2019; 38: 10-47 DOI: 10.1016/j.clnu.2018.05.024. (PMID: 30005900)
- 34 Schaller SJ, Kiselev J, Loidl V. et al. Prehabilitation of elderly frail or pre-frail patients prior to elective surgery (PRAEP-GO): study protocol for a randomized, controlled, outcome assessor-blinded trial. Trials 2022; 23: 468 DOI: 10.1186/s13063-022-06401-x. (PMID: 35668532)
- 35 Bohannon RW, Crouch RH. Two-Minute Step Test of Exercise Capacity: Systematic Review of Procedures, Performance, and Clinimetric Properties. J Geriatr Phys Ther 2019; 42: 105-112 DOI: 10.1519/JPT.0000000000000164. (PMID: 29210933)
- 36 Podsiadlo D, Richardson S. The timed „Up & Go“: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 1991; 39: 142-148 DOI: 10.1111/j.1532-5415.1991.tb01616.x. (PMID: 1991946)
- 37 Chainani V, Shaharyar S, Dave K. et al. Objective measures of the frailty syndrome (hand grip strength and gait speed) and cardiovascular mortality: A systematic review. Int J Cardiol 2016; 215: 487-493 DOI: 10.1016/j.ijcard.2016.04.068. (PMID: 27131770)
- 38 Zhao H, Wei P, Feng Y. Association Between Frailty and Clinical Outcomes and Quality of Life in Older Adults Following Hip Fracture Surgery: A Retrospective Cohort Study. Anesth Analg 2022; 134: 1035-1042 DOI: 10.1213/ANE.0000000000005841. (PMID: 34958310)