Abstract
Fasting has been widely studied in both prevention and treatment of many neurologic
disorders. Some conditions may be prevented with any type of fasting, while some may
require a stricter regimen. Fasting reduces weight, fasting blood glucose, and insulin
resistance, and favorably alters the gut biome and the immune system. This article
discusses various versions of fasting that have been studied as well as the known
and theoretical mechanisms of how fasting effects the body and the brain. This article
will then review evidence supporting the potential preventive and treatment effects
of fasting in specific neurologic disorders including ameliorating the symptoms of
Parkinson's disease, improving cognition in Alzheimer's disease, reducing migraine
frequency and intensity, and reducing seizure frequency in epilepsy.
Keywords
fasting - prevention - Alzheimer's disease - Parkinson's disease - epilepsy - migraine