SOP Maßnahmen bei Diarrhö unter Therapie mit Checkpoint-Inhibitoren

Checkpoint-Inhibitoren sind ein wichtiger Baustein vieler Tumortherapien, bei deren Einsatz es zum Auftreten immunvermittelter Nebenwirkungen kommen kann. Bei der gastrointestinalen Toxizität stehen Diarrhö und Kolitis im Vordergrund. Dieser Beitrag widmet sich den diagnostischen und therapeutischen Maßnahmen, die möglichst frühzeitig eingeleitet werden sollten, um schwere Komplikationen zu vermeiden.

Schlüsselwörter

Immuntherapie-vermittelte Diarrhoe - Checkpoint-Inhibitoren - Glukokortikoide

• Literatur

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