Behandlungsalternativen für sakrale Chordome

Zusammenfassung

Chordome sind primäre maligne ossäre Tumoren und gehören zu den häufigsten Tumorarten im Sakrum. Die operative Tumorresektion und Radiotherapie sind die Eckpfeiler der Chordomtherapie des Sakrums. Eine komplette Resektion ohne Eröffnen der Tumorkapsel (en bloc Resektion) ist mit der besten Überlebensprognose assoziiert, führt jedoch in einigen Fällen zu einer hohen operativen Morbidität. In diesem Übersichtsartikel beschreiben wir das klinische Krankheitsbild, die Diagnostik, aktuelle Behandlungsalternativen und die wichtigsten entscheidungsrelevanten Faktoren dieser komplexen Tumorerkrankung.

Abstract

Chordomas are primary malignant osseous tumors and are among the most common tumor types in the sacrum. Surgical tumor resection and radiotherapy are the cornerstones of chordoma therapy of the sacrum. Complete resection without opening the tumor capsule (en bloc resection) is associated with the best survival prognosis but results in high operative morbidity in some cases. In this review article, we describe the clinical picture, diagnosis, current treatment alternatives, and key decision-making factors of this complex tumor disease.

Schlüsselwörter

Chordom - Kreuzbein - Behandlung - Resektion - Bestrahlung

Keywords

chordoma - sacrum - treatment - resection - radiotherapy

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