Aktive und passive Bioimplantate bei Stimmlippenlähmung

Andreas Müller

doi:10.1055/a-1708-2881

Laryngo-Rhino-Otologie, Table of Contents

CC BY-NC-ND 4.0 · Laryngorhinootologie 2022; 101(S 01): S144-S159
DOI: 10.1055/a-1708-2881

Referat

Aktive und passive Bioimplantate bei Stimmlippenlähmung

Article in several languages: deutsch | English

Authors

Andreas Müller

Abstract

Zusammenfassung

Stimmlippenlähmungen gehören zu den die Lebensqualität in besonderem Maße beeinträchtigenden Erkrankungen. Während einseitige Paresen zu Glottisschlussinsuffizienz und Heiserkeit führen, gefährden beidseitige Paresen die Atmung und schränken die körperliche Belastungsfähigkeit ein. Zur Therapie persistierender Paresen werden seit über 100 Jahren Bioimplantate eingesetzt. Das Spektrum reicht vom autologen Gewebetransfer über resorbierbare bzw. permanente Injektionsmaterialen bis hin zu Komposit-Thyreoplastikimplantaten und aktiven elektrischen Implantaten für die Neurostimulation des Larynx. Bei indikationsgerechtem Einsatz der Bioimplantate kann die Lebensqualität der betroffenen Patienten heute erheblich verbessert werden.

Schlüsselwörter

Rekurrensparesen - Laryngoplastik - Implantate - Neurostimulation - Lebensqualität

Full Text

References

Literatur
1 Choi J, Son YI, So YK. et al. Posterior glottic gap and age as factors predicting voice outcome of injection laryngoplasty in patients with unilateral vocal fold paralysis. J Laryngol Otol 2012; 126: 260-266
2 Brünings W. Über eine neue Behandlungsmethode der Rekurrenslähmung. Ver Deutsch Laryng 1911; 18: 93-151
3 Ward PH, Hanson DG, Abemayor E. Transcutaneous Teflon injection of the paralyzed vocal cord: A new technique. Laryngoscope 1985; 95: 644-649
4 Varvares MA, Montgomery WW, Hillman RE. Teflon Granuloma of the Larynx: Etiology, Pathophysiology, and Management. Annals of Otology, Rhinology & Laryngology 1995; 104: 511-515
5 Wan-Chiew N, Baki MM, Fauzi MB. et al. In Vitro Evaluation of Biomaterials for Vocal Fold Injection: A Systematic Review. Polymers (Basel) 2021; 13
6 Hess M, Fleischer S, Heckmann B. Therapie der einseitigen Rekurrensparese. HNO Nachrichten 2020; 50: 40-47
7 Simpson B, Rosen C. Principles of Vocal Fold Augmentation. In: Simpson B, Rosen C, Hrsg. Operative Techniques in Laryngology. Berlin, Heidelberg: Springer Berlin Heidelberg; 2008: 91-96
8 Anderson TD, Sataloff RT. Complications of collagen injection of the vocal fold: report of several unusual cases and review of the literature. Journal of Voice 2004; 18: 392-397
9 Brodsky B, Ramshaw JA. Bioengineered Collagens. Subcell Biochem 2017; 82: 601-629
10 Bauman L. CosmoDerm/CosmoPlast (human bioengineered collagen) for the aging face. Facial Plast Surg 2004; 20: 125-128
11 Wang CC, Wu SH, Tu YK. et al. Hyaluronic Acid Injection Laryngoplasty for Unilateral Vocal Fold Paralysis-A Systematic Review and Meta-Analysis. Cells 2020; 9
12 Wang CC, Chang MH, Jiang RS. et al. Laryngeal electromyography-guided hyaluronic acid vocal fold injection for unilateral vocal fold paralysis: a prospective long-term follow-up outcome report. JAMA otolaryngology – head & neck surgery 2015; 141: 264-271
13 Pei YC, Fang TJ, Hsin LJ. et al. Early hyaluronate injection improves quality of life but not neural recovery in unilateral vocal fold paralysis: an open-label randomized controlled study. Restor Neurol Neurosci 2015; 33: 121-130
14 Kim YS, Choi JW, Park JK. et al. Efficiency and durability of hyaluronic acid of different particle sizes as an injectable material for VF augmentation. Acta oto-laryngologica 2015; 135: 1311-1318
15 Fang TJ, Hsin LJ, Chung HF. et al. Office-Based Intracordal Hyaluronate Injections Improve Quality of Life in Thoracic-Surgery-Related Unilateral Vocal Fold Paralysis. Medicine 2015; 94: e1787
16 Miaśkiewicz B, Panasiewicz A, Nikiel K. et al. Comparison of 24-month voice outcomes after injection laryngoplasty with calcium hydroxylapatite or hyaluronic acid in patients with unilateral vocal fold paralysis. Am J Otolaryng 2022; 43
17 Stein J, Eliachar I, Myles J. et al. Histopathologic study of alternative substances for vocal fold medialization. Ann Otol Rhinol Laryngol 2000; 109: 221-226
18 Chhetri DK, Jahan-Parwar B, Hart SD. et al. Injection laryngoplasty with calcium hydroxylapatite gel implant in an in vivo canine model. Ann Otol Rhinol Laryngol 2004; 113: 259-264
19 Kaneko M, Tsuji T, Kishimoto Y. et al. Regenerative Effects of Basic Fibroblast Growth Factor on Restoration of Thyroarytenoid Muscle Atrophy Caused by Recurrent Laryngeal Nerve Transection. J Voice 2018; 32: 645-651
20 Kanazawa T, Komazawa D, Indo K. et al. Single injection of basic fibroblast growth factor to treat severe vocal fold lesions and vocal fold paralysis. Laryngoscope 2015; 125: E338-E344
21 Post A, Fleischer S, Mueller AH. Stimmlippenläsion – Bereits einmalige bFGF-Injektion verbessert Stimmfunktion. Laryngo-Rhino-Otol 2016; 95: 308-309
22 Liang Q, Liu S, Han P. et al. Micronized acellular dermal matrix as an efficient expansion substrate and delivery vehicle of adipose-derived stem cells for vocal fold regeneration. Laryngoscope 2012; 122: 1815-1825
23 Frölich K, Hagen R, Kleinsasser N. Mesenchymale Stammzellen aus Fettgewebe (ASC) – Grundlagen und Anwendung in der HNO-Heilkunde. Laryngorhinootologie 2014; 93: 369-380
24 Truzzi GM, Pauna HF, Bette P. et al. Methods of Fat Tissue Processing for Human Vocal Fold Injection: A Systematic Review. J Voice 2017; 31: 244.e217-244.e221
25 Mazzola RF, Cantarella G, Torretta S. et al. Autologous fat injection to face and neck: from soft tissue augmentation to regenerative medicine. Acta otorhinolaryngologica Italica: organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 2011; 31: 59-69
26 Ricci Maccarini A, Stacchini M, Mozzanica F. et al. Efficacy of trans-nasal fiberendoscopic injection laryngoplasty with centrifuged autologous fat in the treatment of glottic insufficiency due to unilateral vocal fold paralysis. Acta otorhinolaryngologica Italica: organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 2018; 38: 204-213
27 Rihkanen H, Lehikoinen-Söderlund S, Reijonen P. Voice acoustics after autologous fascia injection for vocal fold paralysis. Laryngoscope 1999; 109: 1854-1858
28 Kinnari TJ, Pietarinen P, Geneid A. Vocal fold augmentation under local anaesthesia using autologous fascia. Clin Otolaryngol 2018; 43: 989-991
29 Sittel C, Echternach M, Federspil PA. et al. Polydimethylsiloxane particles for permanent injection laryngoplasty. Ann Otol Rhinol Laryngol 2006; 115: 103-109
30 Mattioli F, Bettini M, Botti C. et al. Polydimethylsiloxane Injection Laryngoplasty for Unilateral Vocal Fold Paralysis: Long-Term Results. J Voice 2017; 31: 517.e511-517.e517
31 Hagemann M, Seifert E. The use of polydimethylsiloxane for injection laryngoplasty. World J Surg 2008; 32: 1940-1947
32 Sittel C, Thumfart WF, Pototschnig C. et al. Textured polydimethylsiloxane elastomers in the human larynx: safety and efficiency of use. J Biomed Mater Res 2000; 53: 646-650
33 Piccinini A, Alicandri-Ciufelli M, Ghidini A. et al. FDG-PET/CT appearance of injected silicone particles (VOX Implants) in head and neck tissues. Acta Biomed 2015; 86: 283-289
34 Drescher R, Müller A, Lesser T. et al. PET/ultrasound fusion for differentiation of Vox implant silicone particles from recurrent cancer. Nuklearmedizin Nuclear medicine 2013; 52: N29-N30
35 Selber J, Sataloff R, Spiegel J. et al. Gore-Tex Medialization Thyroplasty: objective and subjective evaluation. J Voice 2003; 17: 88-95
36 Thompson JD, Hoffman MR, Scholp A. et al. Excised larynx evaluation of subthyroid cartilage approach to medialization thyroplasty. Laryngoscope 2018; 128: 675-681
37 Watanabe K, Hirano A, Honkura Y. et al. Complications of using Gore-Tex in medialization laryngoplasty: case series and literature review. Eur Arch Otorhinolaryngol 2019; 276: 255-261
38 Eichorn D, Park J, Alnouri G. et al. Incidence of and Risk Factors Associated With Vocal Fold Hemorrhage Following Type I Thyroplasty With Gore-Tex Implant. J Voice 2021; 35: 655-658
39 Kim HS, Park SS, Kim MH. et al. Problems associated with alloplastic materials in rhinoplasty. Yonsei Med J 2014; 55: 1617-1623
40 Isshiki N, Morita H, Okamura H. et al. Thyroplasty as a new phonosurgical technique. Acta oto-laryngologica 1974; 78: 451-457
41 Isshiki N, Okamura H, Ishikawa T. Thyroplasty type I (lateral compression) for dysphonia due to vocal cord paralysis or atrophy. Acta oto-laryngologica 1975; 80: 465-473
42 Friedrich G, de Jong FI, Mahieu HF. et al. Laryngeal framework surgery: a proposal for classification and nomenclature by the Phonosurgery Committee of the European Laryngological Society. Eur Arch Otorhinolaryngol 2001; 258: 389-396
43 Payr E. Plastik am Schildknorpel zur Behebung der Folgen einseitiger Stimmbandlähmung. Dtsch Med Wochenschr 1915; 41: 1265-1270
44 Opheim O. Unilateral paralysis of the vocal cord, operative treatment. Acta oto-laryngologica 1955; 45: 226-230
45 Kleinsasser O, Schroeder HG, Glanz H. Medialization of the paralyzed vocal cord by cartilage chips and "wing door thyroplasty". Hno 1982; 30: 275-279
46 Nawka T, Hosemann W. Surgical procedures for voice restoration. GMS current topics in otorhinolaryngology, head and neck surgery 2005; 4: Doc14
47 Tsai M-S, Yang M-Y, Chang G-H. et al. Autologous thyroid cartilage graft implantation in medialization laryngoplasty: a modified approach for treating unilateral vocal fold paralysis. Scientific Reports 2017; 7
48 Meurman Y. Operative mediofixation of the vocal cord in complete unilateral paralysis. AMA Arch Otolaryngol 1952; 55: 544-553
49 Chirilă M, Mureşan R. Vocal fold medialization with tragal cartilage and perichondrium in high vagal paralysis. Eur Arch Otorhinolaryngol 2013; 270: 1873-1878
50 Mesallam TA, Khalil YA, Malki KH. et al. Medialization thyroplasty using autologous nasal septal cartilage for treating unilateral vocal fold paralysis. Clin Exp Otorhinolaryngol 2011; 4: 142-148
51 Isshiki N. Progress in Laryngeal Framework Surgery. Acta oto-laryngologica 2000; 120: 120-127
52 Isshiki N. Recent advances in phonosurgery. Folia phoniatrica 1980; 32: 119-154
53 Koufman JA. Laryngoplasty for vocal cord medialization: an alternative to Teflon. Laryngoscope 1986; 96: 726-731
54 Hess M, Fleischer S. [Laryngeal framework surgery]. Hno 2021;
55 Desuter G, Henrard S, Van Lith-Bijl JT. et al. Shape of Thyroid Cartilage Influences Outcome of Montgomery Medialization Thyroplasty: A Gender Issue. J Voice 2017; 31: 245 e243-245 e248
56 Chrobok V, Pellant A, Sram F. et al. Medialization thyroplasty with a customized silicone implant: clinical experience. Folia Phoniatr Logop 2008; 60: 91-96
57 Harries ML, Morrison M. Short-term results of laryngeal framework surgery--thyroplasty type 1: A pilot study. J Otolaryngol 1995; 24: 281-287
58 Netterville JL, Stone RE, Luken ES. et al. Silastic medialization and arytenoid adduction: the Vanderbilt experience. A review of 116 phonosurgical procedures. Ann Otol Rhinol Laryngol 1993; 102: 413-424
59 Montgomery WW, Montgomery SK. Montgomery thyroplasty implant system. Ann Otol Rhinol Laryngol Suppl 1997; 170: 1-16
60 Montgomery WW, Blaugrund SM, Varvares MA. Thyroplasty: a new approach. Ann Otol Rhinol Laryngol 1993; 102: 571-579
61 Cummings CW, Purcell LL, Flint PW. Hydroxylapatite laryngeal implants for medialization. Preliminary report. Ann Otol Rhinol Laryngol 1993; 102: 843-851
62 Flint PW, Purcell LL, Cummings CW. Pathophysiology and indications for medialization thyroplasty in patients with dysphagia and aspiration. Otolaryngol Head Neck Surg 1997; 116: 349-354
63 Friedrich G. Titanium vocal fold medializing implant: introducing a novel implant system for external vocal fold medialization. Ann Otol Rhinol Laryngol 1999; 108: 79-86
64 Witt RE, Hoffman MR, Friedrich G. et al. Multiparameter analysis of titanium vocal fold medializing implant in an excised larynx model. Ann Otol Rhinol Laryngol 2010; 119: 125-132
65 Malik A, Ramalingam WV, Nilakantan A. et al. Comparison of the use of silastic with titanium prefabricated implant in type I thyroplasty. Braz J Otorhinolaryngol 2014; 80: 156-160
66 van Ardenne N, Vanderwegen J, Van Nuffelen G. et al. Medialization thyroplasty: vocal outcome of silicone and titanium implant. Eur Arch Otorhinolaryngol 2011; 268: 101-107
67 Schneider-Stickler B, Gaechter J, Bigenzahn W. Long-term results after external vocal fold medialization thyroplasty with titanium vocal fold medialization implant (TVFMI). Eur Arch Otorhinolaryngol 2013; 270: 1689-1694
68 Anderson TD, Spiegel JR, Sataloff RT. Thyroplasty revisions: frequency and predictive factors. J Voice 2003; 17: 442-448
69 Rosen CA. Complications of phonosurgery: results of a national survey. Laryngoscope 1998; 108: 1697-1703
70 Woo P, Pearl AW, Hsiung MW. et al. Failed medialization laryngoplasty: management by revision surgery. Otolaryngol Head Neck Surg 2001; 124: 615-621
71 Townsley RB, Anderson J, Siu J. The role of dynamic computerized tomography in revision medialisation thyroplasty. Clin Otolaryngol 2019; 44: 644-647
72 Lundeberg MR, Flint PW, Purcell LL. et al. Revision medialization thyroplasty with hydroxylapatite implants. Laryngoscope 2011; 121: 999-1002
73 Devos M, Schultz P, Guillere F. et al. Thyroplasty for unilateral vocal fold paralysis using an adjustable implant in porous titanium. Eur Ann Otorhinolaryngol Head Neck Dis 2010; 127: 204-212
74 Ho GY, Leonhard M, Denk-Linnert DM. et al. Pre- and intraoperative acoustic and functional assessment of the novel APrevent((R)) VOIS implant during routine medialization thyroplasty. Eur Arch Otorhinolaryngol 2020; 277: 809-817
75 Isshiki N, Tanabe M, Sawada M. Arytenoid adduction for unilateral vocal cord paralysis. Arch Otolaryngol 1978; 104: 555-558
76 Prasad VMN, Remacle M. Medialization Thyroplasty and Arytenoid Adduction for Management of Neurological Vocal Fold Immobility. Advances in oto-rhino-laryngology 2020; 85: 85-97
77 Slavit DH, Maragos NE. Arytenoid adduction and type I thyroplasty in the treatment of aphonia. J Voice 1994; 8: 84-91
78 Hess M, Schroeder D, Puschel K. Sling arytenoid adduction. Eur Arch Otorhinolaryngol 2011; 268: 1023-1028
79 Hess M. Future techniques in phonosurgery. In: Mohan SYKJO, Hrsg. A practical guide to laryngeal framework surgery. Oxford, UK: Compton; 2017: 204ff ISBN: 9781909082076, kein DOI, Buchkapitel
80 Garber D, Wandell GM, Gobillot TA. et al. Safety and Predictors of 30-Day Adverse Events of Laryngeal Framework Surgery: An Analysis of ACS-NSQIP data. Laryngoscope 2021;
81 Zimmermann TM, Orbelo DM, Pittelko RL. et al. Voice outcomes following medialization laryngoplasty with and without arytenoid adduction. Laryngoscope 2019; 129: 1876-1881
82 Chester MW, Stewart MG. Arytenoid adduction combined with medialization thyroplasty: an evidence-based review. Otolaryngol Head Neck Surg 2003; 129: 305-310
83 Yılmaz T, Özer F. Unilateral Vocal Fold Paralysis With Large Posterior Glottic Gap: Is Arytenoid Procedure Necessary?. Ann Otol Rhinol Laryngol 2021; 34894211045637
84 Zeitels SM, Hochman I, Hillman RE. Adduction arytenopexy: a new procedure for paralytic dysphonia with implications for implant medialization. Ann Otol Rhinol Laryngol Suppl 1998; 173: 2-24
85 Zeitels SM, Hillman RE, Desloge RB. et al. Cricothyroid subluxation: a new innovation for enhancing the voice with laryngoplastic phonosurgery. Ann Otol Rhinol Laryngol 1999; 108: 1126-1131
86 Rovó L, Ambrus A, Tóbiás Z. et al. A Novel Endoscopic Arytenoid Medialization for Unilateral Vocal Fold Paralysis. Laryngoscope 2021; 131: E903-e910
87 Ekbom DC, Orbelo DM, Sangaralingham LR. et al. Medialization laryngoplasty/arytenoid adduction: U.S. outcomes, discharge status, and utilization trends. Laryngoscope 2019; 129: 952-960
88 Colledge L. On the possibility of restoring movement to a paralysed vocal cord by nerve anastomosis : (An experimental inquiry.). Br Med J 1925; 1: 547-548
89 Tucker HM. Human laryngeal reinnervation. Laryngoscope 1976; 86: 769-779
90 Tucker HM. Reinnervation of the unilaterally paralyzed larynx. Ann Otol Rhinol Laryngol 1977; 86: 789-794
91 Crumley RL. Selective reinnervation of vocal cord adductors in unilateral vocal cord paralysis. Ann Otol Rhinol Laryngol 1984; 93: 351-356
92 Blackshaw H, Carding P, Jepson M. et al. Does laryngeal reinnervation or type I thyroplasty give better voice results for patients with unilateral vocal fold paralysis (VOCALIST): study protocol for a feasibility randomised controlled trial. BMJ Open 2017; 7: e016871
93 Kodama N, Sanuki T, Kumai Y. et al. Long-term vocal outcomes of refined nerve-muscle pedicle flap implantation combined with arytenoid adduction. Eur Arch Otorhinolaryngol 2015; 272: 681-688
94 Nasr A, Mueller AH. Reinnervation bei einseitiger Stimmlippenlähmung. In: Keilmann A ed 36 Wissenschaftliche Jahrestagung der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie (DGPP). Göttingen: GMS; 2019.
95 Hess MM, Förster G, Böttcher A. et al. Medialization of the ailing vocal fold by means of thyroarytenoid muscle electrostimulation. Laryngorhinootologie 2021; 100
96 Mueller AH. Laryngeal Synkinesis: A Viable Condition for Laryngeal Pacing. In: Remacle JM, Prasad V, Hrsg. Advances in Neurolaryngology. Basel: Karger; 2020: 112
97 Hartmann C. Aerodynamical analysis of the inspiration for an unilateral paralysis of the vocal folds in a synthetic larynx model. Erlangen: Friedrich-Alexander Universität; 2019
98 Hoffman MR, Vandiver B, Derise N. et al. Effect of Medialization on Dyspnea Index in Unilateral Vocal Fold Paralysis. Otolaryngol Head Neck Surg 2021; 0: 1945998211056515
99 Mueller AH, Hagen R, Pototschnig C. et al. Laryngeal pacing for bilateral vocal fold paralysis: Voice and respiratory aspects. Laryngoscope 2017; 127: 1838-1844
100 Mueller AH, Hagen R, Foerster G. et al. Laryngeal pacing via an implantable stimulator for the rehabilitation of subjects suffering from bilateral vocal fold paralysis: A prospective first-in-human study. Laryngoscope 2016; 126: 1810-1816
101 Bakhsh Z, Crevier-Buchman L. Stroboscopic assessment of unilateral vocal fold paralysis: a systematic review. Eur Arch Otorhinolaryngol 2019; 276: 2377-2387
102 King BT. New and function-restoring operation for bilateral abductor cord paralysis: preliminary report. journal of the American Medical Association 1939; 112: 814-823
103 Schobel H. [Dilatation of the glottis in bilateral vocal cord paralysis. Review of various surgical procedures and a report of personal experience using a functional lateral fixation surgical technic]. Hno 1986; 34: 485-495
104 Ejnell H, Mansson I, Hallen O. et al. A simple operation for bilateral vocal cord paralysis. Laryngoscope 1984; 94: 954-958
105 Lichtenberger G. Endo-extralaryngeal needle carrier instrument. Laryngoscope 1983; 93: 1348-1350
106 Lichtenberger G, Toohill RJ. The endo-extralaryngeal needle carrier. Otolaryngol Head Neck Surg 1991; 105: 755-756
107 Lichtenberger G, Toohill RJ. Technique of endo-extralaryngeal suture lateralization for bilateral abductor vocal cord paralysis. Laryngoscope 1997; 107: 1281-1283
108 Lichtenberger G. Reversible immediate and definitive lateralization of paralyzed vocal cords. Eur Arch Otorhinolaryngol 1999; 256: 407-411
109 Lichtenberger G. Reversible lateralization of the paralyzed vocal cord without tracheostomy. Ann Otol Rhinol Laryngol 2002; 111: 21-26
110 Rovo L, Venczel K, Torkos A. et al. Endoscopic arytenoid lateropexy for isolated posterior glottic stenosis. Laryngoscope 2008; 118: 1550-1555
111 Kukwa W, Kukwa A, Piaskowska M. et al. Submucosal arytenoidectomy with laterofixation in the treatment of bilateral vocal fold paralysis following lung cancer. Otolaryngol Pol 2007; 61: 17-20
112 Rovo L, Madani S, Sztano B. et al. A new thread guide instrument for endoscopic arytenoid lateropexy. Laryngoscope 2010; 120: 2002-2007
113 Szakacs L, Sztano B, Matievics V. et al. A comparison between transoral glottis-widening techniques for bilateral vocal fold immobility. Laryngoscope 2015; 125: 2522-2529
114 Matievics V, Bach A, Sztano B. et al. Functional outcomes of endoscopic arytenoid abduction lateropexy for unilateral vocal cord paralysis with dyspnea. Eur Arch Otorhinolaryngol 2017; online first
115 Thornell WC. A new intralaryngeal approach in arytenoidectomy in bilateral abductor paralysis of the vocal cords; report of three cases. Arch Otolaryngol 1949; 50: 634-639 illust
116 Kleinsasser O. Endolaryngeal arytenoidectomy and submucous hemichordectomy for the widening of the glottis in bilateral abductor paralysis. Monatsschr Ohrenheilkd Laryngorhinol 1968; 102: 443-446
117 Lim RY. Laser arytenoidectomy. Arch Otolaryngol 1985; 111: 262-263
118 Ossoff RH, Sisson GA, Duncavage JA. et al. Endoscopic laser arytenoidectomy for the treatment of bilateral vocal cord paralysis. Laryngoscope 1984; 94: 1293-1297
119 Remacle M, Lawson G, Mayne A. et al. Subtotal carbon dioxide laser arytenoidectomy by endoscopic approach for treatment of bilateral cord immobility in adduction. Ann Otol Rhinol Laryngol 1996; 105: 438-445
120 Sato K, Umeno H, Nakashima T. Laser arytenoidectomy for bilateral median vocal fold fixation. Laryngoscope 2001; 111: 168-171
121 Dennis DP, Kashima H. Carbon dioxide laser posterior cordectomy for treatment of bilateral vocal cord paralysis. Ann Otol Rhinol Laryngol 1989; 98: 930-934
122 Reker U, Rudert H. [Modified posterior Dennis and Kashima cordectomy in treatment of bilateral recurrent nerve paralysis]. Laryngorhinootologie 1998; 77: 213-218
123 Eckel HE. Laser surgical microlaryngoscopic glottis dilatation in the treatment of recurrent bilateral nerve paralysis. Surgical technique and results. Laryngorhinootologie 1991; 70: 17-20
124 Bigenzahn W, Hoefler H. Minimally invasive laser surgery for the treatment of bilateral vocal cord paralysis. Laryngoscope 1996; 106: 791-793
125 Crumley RL. Endoscopic laser medial arytenoidectomy for airway management in bilateral laryngeal paralysis. Ann Otol Rhinol Laryngol 1993; 102: 81-84
126 Kashima HK. Bilateral vocal fold motion impairment: pathophysiology and management by transverse cordotomy. Ann Otol Rhinol Laryngol 1991; 100: 717-721
127 Rontal M, Rontal E. Use of laryngeal muscular tenotomy for bilateral midline vocal cord fixation. Ann Otol Rhinol Laryngol 1994; 103: 583-589
128 Maurizi M, Paludetti G, Galli J. et al. CO2 laser subtotal arytenoidectomy and posterior true and false cordotomy in the treatment of post-thyroidectomy bilateral laryngeal fixation in adduction. Eur Arch Otorhinolaryngol 1999; 256: 291-295
129 Pia F, Pisani P, Aluffi P. CO(2) laser posterior ventriculocordectomy for the treatment of bilateral vocal cord paralysis. Eur Arch Otorhinolaryngol 1999; 256: 403-406
130 Sapundzhiev N, Lichtenberger G, Eckel HE. et al. Surgery of adult bilateral vocal fold paralysis in adduction: history and trends. Eur Arch Otorhinolaryngol 2008; 265: 1501-1514
131 Nawka T, Sittel C, Gugatschka M. et al. Permanent transoral surgery of bilateral vocal fold paralysis: a prospective multi-center trial. Laryngoscope 2015; 125: 1401-1408
132 Nawka T, Sittel C, Arens C. et al. Voice and respiratory outcomes after permanent transoral surgery of bilateral vocal fold paralysis. Laryngoscope 2015; 125: 2749-2755
133 Nawka T, Gugatschka M, Kolmel JC. et al. Therapy of bilateral vocal fold paralysis: Real world data of an international multi-center registry. PLoS One 2019; 14: e0216096
134 Inglis AF, Perkins JA, Manning SC. et al. Endoscopic posterior cricoid split and rib grafting in 10 children. Laryngoscope 2003; 113: 2004-2009
135 Modi VK. Endoscopic posterior cricoid split with rib grafting. Advances in oto-rhino-laryngology 2012; 73: 116-122
136 Gerber ME, Modi VK, Ward RF. et al. Endoscopic posterior cricoid split and costal cartilage graft placement in children. Otolaryngol Head Neck Surg 2013; 148: 494-502
137 Dahl JP, Purcell PL, Parikh SR. et al. Endoscopic posterior cricoid split with costal cartilage graft: A fifteen-year experience. Laryngoscope 2017; 127: 252-257
138 Ruda J, Dahl J, McClain W. et al. Multi-institutional Evaluation of Radiologic Findings Associated With Pediatric Congenital Idiopathic Bilateral Vocal Fold Dysfunction. Otolaryngol Head Neck Surg 2021; 164: 1314-1321
139 Hsu AK, Rosow DE, Wallerstein RJ. et al. Familial congenital bilateral vocal fold paralysis: a novel gene translocation. International journal of pediatric otorhinolaryngology 2015; 79: 323-327
140 Giotakis AI, Pototschnig C. Prognosis of congenital idiopathic abductor laryngeal paralysis with laryngeal electromyography. The Laryngoscope 2020; 130: E252-E257
141 Berkowitz RG. Natural history of tracheostomy-dependent idiopathic congenital bilateral vocal fold paralysis. Otolaryngol Head Neck Surg 2007; 136: 649-652
142 Mueller A, Blechschmidt K. Abstract: Our concept on larynx-pacing. In: Andrea M ed 5th Congress of the EuropeanLaryngological Society (Lisbon 10-13 July 2004). Lisbon: European Archives of Oto-Rhino-Laryngology and Head & Neck. 2004: 998
143 Volk GF, Hagen R, Pototschnig C. et al. Laryngeal electromyography: a proposal for guidelines of the European Laryngological Society. Eur Arch Otorhinolaryngol 2012; 269: 2227-2245
144 Foerster G, Mueller AH. Laryngeal EMG: Preferential damage of the posterior cricoarytenoid muscle branches especially in iatrogenic recurrent laryngeal nerve lesions. Laryngoscope 2018; 128: 1152-1156
145 Stennert E. The autoparalytic syndrome – a leading symptom of postparetic facial function. Archives of oto-rhino-laryngology 1982; 236: 97-114
146 Crumley RL. Mechanisms of synkinesis. Laryngoscope 1979; 89: 1847-1854
147 Crumley RL. Laryngeal synkinesis: its significance to the laryngologist. Ann Otol Rhinol Laryngol 1989; 98: 87-92
148 Crumley RL. Laryngeal synkinesis revisited. Ann Otol Rhinol Laryngol 2000; 109: 365-371
149 Zealear DL, Billante CR. Synkinesis and Dysfunctional Reinnervation of the Larynx. In: Sulica L, Blitzer A, Hrsg. Vocal Fold Paralysis. Berlin Heidelberg New York: Springer; 2006: 17-32 Buchkapitel, kein DOI
150 Statham MM, Rosen CA, Smith LJ. et al. Electromyographic laryngeal synkinesis alters prognosis in vocal fold paralysis. The Laryngoscope 2009; NA-NA
151 Mueller AH. Laryngeal Synkinesis – a viable condition for Laryngeal Pacing. In: Remacle JM, Prasad V, Hrsg. Advances in Neurolaryngology. Basel: Karger; 2019
152 Mueller AH, Pototschnig C. Recurrent Laryngeal Nerve Stimulator. Otolaryngol Clin North Am 2020; 53: 145-156
153 Mueller AH, Marie J-P, Mardion NB. et al. Reinnervation/Pacing for Bilateral Vocal Fold Paralysis. In: Amin MR, Johns MM, Hrsg. Decision Making in Vocal Fold Paralysis. Cham: Springer Switzerland; 2019: 257-268
154 Akbulut S, Betka J, Chrobok V. et al. Pacing/Reinnervation. In: Rehabilitation and Prognosis of Voice Disorders. In: am Zehnhoff-Dinnesen A, Wiskirska-Woznica B, Neumann K et al., Hrsg. Phoniatrics I: Fundamentals – Voice Disorders – Disorders of Language and Hearing Development.. Berlin, Heidelberg: Springer Berlin Heidelberg; 2020: 435-536
155 Mueller AH, Klinge K. RLN Paralysis – Update on Reinnervation and Neurostimulation. Medical Research Archives 2018; 6
156 Bach A, Sztano B, Matievics V. et al. Isolated Recovery of Adductor Muscle Function Following Bilateral Recurrent Laryngeal Nerve Injuries; Laryngoscope: 2019. 129. 2334-2340
157 Mueller AH. Laryngeal Pacing. In: Sittel C, Guntinas-Lichius O, Hrsg. Neurolaryngology. Cham: Springer International Publishing; 2018: 173-183
158 Forster G, Arnold D, Bischoff SJ. et al. Laryngeal pacing in minipigs: in vivo test of a new minimal invasive transcricoidal electrode insertion method for functional electrical stimulation of the PCA. Eur Arch Otorhinolaryngol 2013; 270: 225-231
159 Mueller AH. Laryngeal Neuroprothesis. ENT & Audiology News 2012; 21: 47-48
160 Förster G, Schubert H, Arnold D. et al. Laryngeal pacemaker—acute and chronic minimal invasive electrode implantations in pig larynx Abstracts from the 8th Congress of the European Laryngological Society, 1–4 September 2010, Vienna, Austria. Eur Arch Otorhinolaryngol 2011; 268: 759-800
161 Mueller AH. Laryngeal pacing for bilateral vocal fold immobility. Current opinion in otolaryngology & head and neck surgery 2011; 19: 439-443
162 Zealear DL, Dedo HH. Control of paralysed axial muscles by electrical stimulation. Acta oto-laryngologica 1977; 83: 514-527
163 Sanders I. Electrical stimulation of laryngeal muscle. Otolaryngol Clin North Am 1991; 24: 1253-1274
164 Kano S, Sasaki CT. Pacing parameters of the canine posterior cricoarytenoid muscle. Ann Otol Rhinol Laryngol 1991; 100: 584-588
165 Zrunek M, Carraro U, Catani C. et al. [Functional electrostimulation of the denervated posticus muscle in an animal experiment: histo- and biochemical results]. Laryngol Rhinol Otol (Stuttg) 1986; 65: 621-627
166 Otto RA, Davis W, Betten JR. et al. Electrophysiologic pacing of vocal cord abductors in bilateral recurrent laryngeal nerve paralysis. Am J Surg 1985; 150: 447-451
167 Broniatowski M, Kaneko S, Jacobs G. et al. Laryngeal pacemaker. II. Electronic pacing of reinnervated posterior cricoarytenoid muscles in the canine. Laryngoscope 1985; 95: 1194-1198
168 Obert PM, Young KA, Tobey DN. Use of direct posterior cricoarytenoid stimulation in laryngeal paralysis. Arch Otolaryngol 1984; 110: 88-92
169 Bergmann K, Warzel H, Eckhardt HU. et al. Respiratory rhythmically regulated electrical stimulation of paralyzed laryngeal muscles. Laryngoscope 1984; 94: 1376-1380
170 Zealear DL, Rainey CL, Herzon GD. et al. Electrical pacing of the paralyzed human larynx. Ann Otol Rhinol Laryngol 1996; 105: 689-693
171 Zealear DL, Billante CR, Courey MS. et al. Reanimation of the paralyzed human larynx with an implantable electrical stimulation device. Laryngoscope 2003; 113: 1149-1156
172 Müller AH, Hagen R, Förster G. et al. Laryngeal Pacing for the treatment of bilateral vocal fold paralysis: 24 m results of aprospective first-in-human study. In: Dietz A ed 91 Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie eV, Bonn – Welche Qualität macht den Unterschied. Berlin/Online: Laryngorhinootologie. 2020.
173 Marie JP, Laquerriere A, Lerosey Y. et al. Selective resection of the phrenic nerve roots in rabbits. Part I: Cartography of the residual innervation. Respir Physiol 1997; 109: 127-138 S0034568797000479 [pii]
174 Marie JP, Dehesdin D, Ducastelle T. et al. Selective reinnervation of the abductor and adductor muscles of the canine larynx after recurrent nerve paralysis. Ann Otol Rhinol Laryngol 1989; 98: 530-536
175 Marie J. Contribution à l’étude de la réinnervation laryngée expérimentale; intérêt du nerf phrénique. Laryngeal reinnervation: special interest with the phrenic nerve. PhD Thesis. University of Rouen, Normandy, France 1999; p300: 1999
176 Marina MB, Marie J-P, Birchall MA. Laryngeal reinnervation for bilateral vocal fold paralysis. Current opinion in otolaryngology & head and neck surgery 2011; 19
177 Dunya G, Orb QT, Smith ME. et al. A Review of Treatment of Bilateral Vocal Fold Movement Impairment. Current Otorhinolaryngology Reports 2021;
178 Li M, Chen S, Zheng H. et al. Reinnervation of bilateral posterior cricoarytenoid muscles using the left phrenic nerve in patients with bilateral vocal fold paralysis. PLoS One 2013; 8: e77233
179 Li M, Zheng H, Chen S. et al. Selective reinnervation using phrenic nerve and hypoglossal nerve for bilateral vocal fold paralysis. Laryngoscope 2019; 129: 2669-2673
180 Lee JW, Bon-Mardion N, Smith ME. et al. Bilateral Selective Laryngeal Reinnervation for Bilateral Vocal Fold Paralysis in Children. JAMA otolaryngology-- head & neck surgery 2020; 146: 401-407
181 Li M, Chen D, Song X. et al. The effect of patient age on the success of laryngeal reinnervation. Eur Arch Otorhinolaryngol 2014; 271: 3241-3247