Die Migränepersönlichkeit

ZUSAMMENFASSUNG

Die Suche nach einer Migränepersönlichkeit ist in der Medizingeschichte nicht neu. Es gab verschiedene Ansätze, alle Menschen mit Migräne einem bestimmten Persönlichkeitstypus zuzuordnen. Dies ist aus heutiger Sicht gescheitert, obwohl es Verhaltensmerkmale und kognitive Besonderheiten gibt, die bei der Mehrzahl der Menschen mit Migräne auftreten. Dazu gehören ein unspezifisch erhöhter Neurotizismus-Score (am ehesten durch die Schmerzen bedingt) und eine mangelnde Habituation auf kognitive Reize zwischen den Migräneattacken. Ein weiterer Aspekt der „Migränepersönlichkeit“ ist die Komorbidität mit einigen psychiatrischen Erkrankungen wie Depression und Angsterkrankungen. Hierbei handelt es sich möglicherweise um gemeinsame pathophysiologische Grundlagen, die aber nicht in ein konsistentes psychiatrisches Krankheitsprofil bei Menschen mit Migräne münden. Weiterhin muss bei den Auswirkungen der Migräne auf die Betroffenen auch die deutlich beeinträchtigte Lebensqualität berücksichtigt werden, die inzwischen mit krankheitsspezifischen Instrumenten erfasst wird. Abschließend gibt dieser Artikel auch Hinweise, wie die o. g. spezifischen Aspekte der Migränepatienten im ärztlichen Gespräch berücksichtigt werden können.

ABSTRACT

Approaches to detect a specific migraine personality are not new in the history of medicine. Different scientific ways have been described to categorize all migraine subjects into one personality. This has failed to date although there are behavioral and cognitive properties which can be observed in a majority of migraine subjects. In particular, an increased neuroticism (due to the pain) and lack of cognitive habituation should be considered in this context. Another aspect of “migraine personality” is the comorbidity with some psychiatric disorders such as depression and anxiety disorders. A common pathophysiological background can be assumed; however, this does not lead to a specific psychiatric profile of all migraine subjects. Further, consequences of the impaired quality of life in subjects with migraine should be considered which are nowadays evaluated by disease specific measures. Finally, this article gives recommendations how to integrate these aspects into the consultation of subjects with migraine.

Schlüsselwörter

Migräne - Persönlichkeit - kognitive Funktionen - Komorbidität - Lebensqualität

Key words

Migraine - personality - cognitive functions - quality of life - comorbidity

Publikationsverlauf

Artikel online veröffentlicht:
09. Februar 2022

• Literatur

• 1 Wolff HG. Personality features and reactions of subjects with migraine. Arch Neurol 1937; 37: 895-921
• 2 Alvarez WC. The migrainous personality and constitution; the essential features of the disease; a study of 500 cases. Am J Med Sci 1947; 213: 1-8
• 3 Friedmann AP, Storch TC von, Merritt HH. Migraine and tension headaches: a clinical study in 2000 cases. Neurology 1954; 04: 773-778
• 4 Peters UH, Schäfer ML, Philipp M. Psychosomatische Therapie der Migräne. Z Psychosom Med Psychoanal 1981; 27: 338-46
• 5 Schäfer ML, Peters UH, Philipp M. Psychodynamik der Migräne. Psychother Psychosom Med Psychol 1982; 32: 43-46
• 6 Silberstein SD, Lipton RB, Breslau N. Migraine: association with personality characteristics and psychopathology. Cephalalgia 1995; 15: 358-69
• 7 Huber D. Migräne – Persönlichkeit und Stressbewältigung: Eine kritische Übersicht. Psychother Psych Med 2003; 53: 432-43
• 8 Lucas RN. Migraine in twins. J Psychosom Res 1977; 21: 147-156
• 9 Persson B. Growth environment and personality in adult migraineurs and their migraine-free siblings. Headache 1997; 37: 159-168
• 10 Breslau N, Chilcoat HD, Andreski P. Further evidence on the link between migraine and neuroticism. Neurology 1996; 47: 663-667
• 11 Sacks O. Migraine: revised and expanded. Berkely: University of California Press 1992
• 12 Henryk-Gutt R, Rees WL. Psychological aspects of migraine. J Psychosom Res 1973; 17: 141-153
• 13 Meyer B, Keller A, Wöhlbier HG. et al Progressive muscle relaxation reduces migraine frequency and normalizes amplitudes of contingent negative variation (CNV). J HeadachePain 2016; 17: 37
• 14 Kropp P, Siniatchkin M, Gerber WD. On the pathophysiology of migraine – links for “empirically based treatment” with neurofeedback. Appl Psychophysiol Biofeedback 2002; 27: 203-213
• 15 Kropp P, Linstedt U, Niederberger U. et al Contingent negative variation and attentional performance in humans. Neurol Res 2001; 23: 647-650
• 16 De Tommaso M, Delussi M. Nociceptive blink reflex habituation biofeedback in migraine. Funct Neurol 2017; 32: 123-130
• 17 Kropp P, Brecht IB, Niederberger U. et al Time-dependent post imperative negative variation indicates adaptation and problem solving in migraine patients. J Neural Transm 2012; 119: 1213-1221
• 18 Vallesi A. On the utility of the trail making test in migraine with and without aura: a meta-analysis. J Headache Pain 2020; 21: 63
• 19 Reitan RM.. Trail Making Test. Reitan Neuropsychology Laboratory, Tucson 1992
• 20 Gil-Gouveia R, Pavão Martins I. Cognition and cognitive impairment in migraine. Curr Pain Headache Rep 2019; 23: 84
• 21 Altamura C, Corbelli I, de Tommaso M. et al Pathophysiological bases of comorbidity in migraine. Front Hum Neurosci 2021; 15: 640574
• 22 Zwart JA, Dyb G, Hagen K. et al Depression and anxiety disorders associated with headache frequency. The nord-trøndelag health study. Eur J Neurol 2003; 10: 147-52
• 23 Scher AI, Midgette L, Lipton RB. Risk factors for headache chronification. Headache 2008; 48: 16-25
• 24 Kelman L. The triggers or precipitants of the acute migraine attack. Cephalalgia 2007; 27: 394-402
• 25 Jette N, Patten S, Williams J. et al Comorbidity of migraine and psychiatric disorders – a national population-based study. Headache 2008; 48: 501-516
• 26 Rossi P, Di Lorenzo G, Malpezzi MG. et al Depressive symptoms and insecure attachment as predictors of disability in a clinical population of patients with episodic and chronic migraine. Headache 2005; 45: 561-570
• 27 Amoozegar F. Depression comorbidity in migraine. Int Rev Psychiatry 2017; 29: 504-515
• 28 Peck KR, Smitherman TA, Baskin SM. Traditional and alternative treatments for depression: implications for migraine management. Headache 2015; 55: 351-355
• 29 Leung A, Shirvalkar P, Chen R. et al Transcranial magnetic stimulation for pain, headache, and comorbid depression: INS-NANS expert consensus panel review and recommendation. Neuromodulation 2020; 23: 267-290
• 30 Dresler T, Caratozzolo S, Guldolf K. et al Understanding the nature of psychiatric comorbidity in migraine: a systematic review focused on interactions and treatment implications. J Headache Pain 2019; 20: 51
• 31 Leo RJ, Singh J. Migraine headache and bipolar disorder comorbidity: a systematic review of the literature and clinical implications. Scand J Pain 2016; 11: 136-145
• 32 Yamada K, Moriwaki K, Oiso H. et al High prevalence of comorbidity of migraine in outpatients with panic disorder and effectiveness of psychopharmacotherapy for both disorders: a retrospective open label study. Psychiatry Res 2011; 185: 145-148
• 33 Buse DC, Silberstein SD, Manack AN. et al Psychiatric comorbidities of episodic and chronic migraine. J Neurol 2013; 260: 1960-1969
• 34 Curone M, Tullo V, Lovati C. et al Prevalence and profile of obsessive-compulsive trait in patients with chronic migraine and medication overuse. Neurol Sci 2014; 35 (Suppl. 01) S185-S187
• 35 Curone M, D’Amico D, Bussone G. Obsessive-compulsive aspects as predictors of poor response to treatments in patients with chronic migraine and medication overuse. Neurol Sci 2012; 33 (Suppl. 01) S211-S213
• 36 Peterlin BL, Tietjen G, Meng S. et al Post-traumatic stress disorder in episodic and chronic migraine. Headache 2008; 48: 517-522
• 37 Lake AE, Rains JC, Penzien DB. et al Headache and psychiatric comorbidity: historical context, clinical implications, and research relevance. Headache 2005; 45: 493-506
• 38 Tarantino S, De Ranieri C, Dionisi C. et al Migraine equivalents and related symptoms, psychological profile and headache features: which relationship?. J Headache Pain 2015; 16: 536
• 39 Scher AI, Stewart WF, Lipton RB. Caffeine as a risk factor for chronic daily headache: a population-based study. Neurology 2004; 63: 2022-2027
• 40 Schwedt TJ, Schlaggar BL, Mar S. et al Atypical resting-state functional connectivity of affective pain regions in chronic migraine. Headache 2013; 53: 737-751
• 41 GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017; 390: 1211-1259
• 42 GBD 2015 Neurological Disorders Collaborator Group. Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet Neurol 2017; 16: 877-897
• 43 Solomon GD. Evolution of the measurement of quality of life in migraine. Neurology 1997; 48 (Suppl. 03) S10-15
• 44 Wagner TH, Patrick DL, Galer BS. et al A new instrument to assess the long-term quality of life effects from migraine: development and psychometric testing of the MSQOL. Headache 1996; 36 (08) 484-92
• 45 Becker G, Merk CS, Meffert C. et al Measuring individual quality of life in patients receiving radiation therapy: the SEIQoL-Questionnaire. Qual Life Res 2014; 23: 2025-2030
• 46 Kosinski M, Bayliss MS, Bjorner JB. et al A six-item short-form survey for measuring headache impact: the HIT-6. Qual Life Res 2003; 12: 963-974
• 47 Stewart WF, Lipton RB, Whyte J. et al An international study to assess reliability of the Migraine Disability Assessment (MIDAS) score. Neurology 1999; 53: 988-994
• 48 Jacobson GP, Ramadan NM, Aggarwal SK. et al The Henry Ford Hospital Headache Disability Inventory (HDI). Neurology 1994; 44: 837-842
• 49 Agosti R, Chrubasik JE, Kohlmann T. Ein Instrument zur Beurteilung von Kopfschmerzen. Hausarzt Praxis 2009; 08: 24-25
• 50 Bauer B, Evers S, Gralow I. et al Psychosoziale Beeinträchtigung durch chronische Kopfschmerzen. Evaluation des Inventars zur Beeinträchtigung durch Kopfschmerzen (IBK). Nervenarzt 1999; 70: 522-529
• 51 Kawata AK, Coeytaux RR, Devellis RF. et al Psychometric properties of the HIT-6 among patients in a headache-specialty practice. Headache 2005; 45: 638-643
• 52 Tassorelli C, Diener HC, Dodick DW. et al Guidelines of the International Headache Society for controlled trials of preventive treatment of chronic migraine in adults. Cephalalgia 2018; 38: 815-832
• 53 Diener HC, Tassorelli C, Dodick DW. et al Guidelines of the International Headache Society for controlled trials of preventive treatment of migraine attacks in episodic migraine in adults. Cephalalgia 2020; 40: 1026-1044
• 54 McGinley JS, Houts CR, Nishida TK. et al Systematic review of outcomes and endpoints in preventive migraine clinical trials. Headache 2021; 61: 253-262
• 55 Lipton RB, Tepper SJ, Reuter U. et al Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study. Neurology 2019; 92: e2250-e2260
• 56 Okonkwo R, Tockhorn-Heidenreich A. et al Efficacy of galcanezumab in patients with migraine and history of failure to 3–4 preventive medication categories: subgroup analysis from CONQUER study. J Headache Pain 2021; 22: 113
• 57 Leplus A, Fontaine D, Donnet A. et al Long-Term efficacy of occipital nerve stimulation for medically intractable cluster headache. Neurosurgery 2021; 88: 375-383
• 58 Zhao L, Chen J, Li Y. et al The Long-term Effect of Acupuncture for Migraine Prophylaxis: A Randomized Clinical Trial. JAMA Intern Med 2017; 177 (04) 508-515