Racial and Ethnic Disparities in Cancer-Associated Thrombosis

Courteney Wiredu; Norrisa Haynes; Carmen Guerra; Bonnie Ky

doi:10.1055/a-1674-0259

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 2022; 122(05): 662-665
DOI: 10.1055/a-1674-0259

Invited Mini Series: Novel Clinical Concepts in Thrombosis

Racial and Ethnic Disparities in Cancer-Associated Thrombosis

Authors

Courteney Wiredu

¹Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States
Norrisa Haynes

²Division of Cardiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States

³Leonard Davis Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States
Carmen Guerra

³Leonard Davis Institute, University of Pennsylvania, Philadelphia, Pennsylvania, United States

⁴Division of Internal Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States

⁵Abramson Cancer Center, Philadelphia, Pennsylvania, United States

⁶Department of Epidemiology, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania, United States
Bonnie Ky

²Division of Cardiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States

⁵Abramson Cancer Center, Philadelphia, Pennsylvania, United States

⁶Department of Epidemiology, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania, United States

Abstract

Active malignancy increases the risk of developing venous thromboembolism (VTE) by four- to seven-fold. The risk of VTE, including deep vein thrombosis and pulmonary embolism, in patients with cancer varies based on several clinical factors, such as cancer stage and age. However, race and ethnicity are also associated with increased VTE risk. Black (African American) patients with cancer have a higher risk of developing VTE than White patients, while Asian/Pacific Islanders have a lower risk. Studies on cancer-associated thrombosis demonstrate a need to advance our understanding of both the biologic and sociologic underpinnings of the observed differences according to race. Addressing the causes of these disparities can better health outcomes for historically underserved patient populations.

Keywords

ethnic groups - neoplasms - race - risk factors - venous thromboembolism

Full Text

References

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