Hamostaseologie 2021; 41(05): 356-364
DOI: 10.1055/a-1554-6416
Review Article

COVID-19 and the Incidence of Acute Myocardial Injury

Lars Mizera
1  Department of Cardiology and Angiology, University of Tuebingen, Tuebingen, Germany
,
Oliver Borst
1  Department of Cardiology and Angiology, University of Tuebingen, Tuebingen, Germany
2  DFG Heisenberg Group Thrombocardiology
› Author Affiliations

Abstract

Cardiovascular manifestations are frequent in COVID-19 infection and are predictive of adverse outcomes. Elevated cardiac biomarkers are common findings in patients with cardiovascular comorbidities and severe COVID-19 infection. Troponin, inflammatory and thrombotic markers may also improve risk prediction in COVID-19. In our comprehensive review, we provide an overview of the incidence, potential mechanisms and outcome of acute cardiac injury in COVID-19. Thereby, we discuss coagulation abnormalities in sepsis and altered immune response as contributing factors favoring myocardial injury. We further highlight the role of endothelial damage in the pathophysiological concepts. Finally, observational studies addressing the incidence of myocardial infarction during COVID-19 pandemic are discussed.



Publication History

Received: 12 May 2021

Accepted: 19 July 2021

Publication Date:
25 October 2021 (online)

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