CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2021; 81(12): 1301-1306
DOI: 10.1055/a-1541-7964
GebFra Science

Recommendations of the AGG (Section Maternal Disease) for Myasthenia Gravis in Pregnancy

Article in several languages: English | deutsch
Maritta Kühnert
1   Obstetrics, UFK Marburg, Marburg, Germany
Markus Schmidt
2   Gynecology & Obstetrics, Sana Kliniken Duisburg GmbH, Duisburg, Germany
Bettina Kuschel
3   Frauenklinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, München, Germany
Ute Margaretha Schäfer-Graf
4   Perinatalzentrum, Klinik für Gynäkologie und Geburtshilfe, Berlin, Germany
› Author Affiliations


Myasthenia gravis is an autoimmune disease with a range of clinical presentations which manifest as combinations of weakness of the ocular, bulbar, and respiratory muscle groups and muscles of the extremities. Young women of reproductive age are most commonly affected. Preconception planning, the impact of pregnancy, prepartum management, drug therapy in pregnancy, myasthenic and cholinergic crises, fetal monitoring, peripartum management including analgesia and anesthesia during labor and cesarean section as well as neonatal management and neonatal myasthenia gravis are described here and the appropriate recommendations are given.

Publication History

Received: 18 June 2021

Accepted after revision: 29 June 2021

Publication Date:
08 December 2021 (online)

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