Z Geburtshilfe Neonatol
DOI: 10.1055/a-1498-2940
Case Report

Gitelman Syndrome in Pregnancy: A Clinical Challenge

1  Perinatology, Ankara Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Turkey
,
2  Division of Perinatology, Department of Obstetrics and Gynecology, Hacettepe Universitesi Tip Fakultesi, Altindag, Turkey
,
Harun Egemen Tolunay
1  Perinatology, Ankara Etlik Zübeyde Hanım Kadın Hastalıkları Eğitim ve Araştırma Hastanesi, Ankara, Turkey
,
Mustafa Arici
3  Division of Nephrology, Department of Internal Medicine, Hacettepe Universitesi Tip Fakultesi, Altindag, Turkey
,
Aykan Yucel
4  Perinatology, Ankara City Hospital, Cankaya, Turkey
,
Dilek Uygur
4  Perinatology, Ankara City Hospital, Cankaya, Turkey
› Author Affiliations

Abstract

Purpose Disease progress may be affected by pregnancy-related changes, and underlying conditions may also affekt pregnancy outcomes in women with Gitelman syndrome (GS). Case presentation A 35-year-old woman with GS (gravida 2 para 1) was referred to our hospital to start routine antenatal care follow-up at 6 weeks of gestation. At the age of 31, she had been diagnosed with GS after her first uneventful pregnancy. Upon early admission, her serum Mg+level was 0.51 mmol/L and her serum K+level 2.7 mmol/L with normal kidney function tests. She was already taking oral combined potassium citrate and potassium bicarbonate supplementation once a day before pregnancy. At the eighth gestational week, the medication was changed to an oral potassium color sachet of 1.5 gram per day until labor because of the insufficient dosage to maintain optimum potassium levels. She was also taking 365 milligrams of oral magnesium oxide twice a day before and during pregnancy. In the third trimester of the pregnancy, her serum Mg+level was 0.48 mmol/L and serum K+level 2.8 mmol/L. Because of the previous uterine surgery history, she underwent an elective cesarean operation at 39 weeks’ gestation under spinal anesthesia and delivered a healthy 3090-gram female infant.

Conclusion Increased need for potassium and magnesium supplementation should be the critical considerations when managing pregnant patients with GS.



Publication History

Received: 11 February 2020

Accepted after revision: 19 April 2021

Publication Date:
14 June 2021 (online)

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