Subscribe to RSS
DOI: 10.1055/a-1481-9783
Rowell Syndrome Triggered by Pregnancy
Rowell-Syndrom ausgelöst durch Schwangerschaft
Abstract
Rowell syndrome (RS) is a rare disorder associated with lupus erythematosus and erythema multiforme (EM)-like cutaneous lesions. This article presents a 21-year-old female patient who had been followed up for two years with a diagnosis of systemic lupus erythematosus (SLE) and developed RS in the second trimester of pregnancy. Our patient, whose disease exacerbated with skin findings during pregnancy, recovered on cyclosporine treatment without systemic involvement and delivered a healthy baby at term.
Zusammenfassung
Das Rowell-Syndrom (RS) ist eine seltene Erkrankung, die durch eine Assoziation von Lupus erythematodes mit Erythema-multiforme(EM)-ähnlichen Hautläsionen gekennzeichnet ist. Wir stellen eine 21-jährige Patientin vor, die im zweiten Schwangerschaftstrimester, 2 Jahre nach Diagnose eines systemischen Lupus erythematodes (SLE), eine RS entwickelte. Unsere Patientin, deren Krankheit sich während der Schwangerschaft durch Hautbefunde verschlimmerte, erholte sich unter Cyclosporin ohne systemische Beteiligung und brachte termingerecht ein gesundes Baby zur Welt.
Publication History
Publication Date:
17 June 2021 (online)
© 2021. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
References
- 1 Georgiou PE, Politi EN, Katsimbri P. et al. Outcome of lupus pregnancy: a controlled study. Rheumatology 2000; 39: 1014-1019
- 2 Rowell NR, Beck JS, Anderson JR. Lupus erythematosus and erythema multiforme-like lesions: a syndrome with characteristic immunological abnormalities. Archives of dermatology 1963; 88: 176-180
- 3 Zeitouni NC, Funaro D, Cloutier RA. et al. Redefining Rowell’s syndrome. British Journal of Dermatology 2000; 142: 343-346
- 4 Torchia D, Romanelli P, Kerdel FA. Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis associated with lupus erythematosus. Journal of the American Academy of Dermatology 2012; 67: 417-421
- 5 Sharma A, Sharma R. Rowell Syndrome: A case report and review of literature. Internet Journal of Rheumatology and Clinical Immunology 2016; 4: 1
- 6 Clowse ME. Lupus activity in pregnancy. Rheumatic Disease Clinics of North America 2007; 33: 237-252
- 7 Carmona F, Font J, Cervera R. et al. Obstetrical outcome of pregnancy in patients with systemic lupus erythematosus. A study of 60 cases. European Journal of Obstetrics & Gynecology and Reproductive Biology 1999; 83: 137-142
- 8 Lee A, Batra P, Furer V. et al. Rowell syndrome (systemic lupus erythematosus+erythema multiforme). Dermatol Online J 2009; 15: 1
- 9 Müller CS, Hinterberger L, Vogt T. et al. Rowell syndrome – case report with discussion of significance of diagnostic accuracy. Case Reports 2011; 2011: bcr0920114755