Klin Monbl Augenheilkd
DOI: 10.1055/a-1388-7330
Der interessante Fall

Acute Bilateral Angle-Closure Glaucoma Related to Intranasal Cocaine Abuse

Akutes bilaterales Engwinkelglaukom im Zusammenhang mit intranasalem Missbrauch von Kokain
Ophthalmology, Alicante General University Hospital, Alicante, Spain
,
Ophthalmology, Alicante General University Hospital, Alicante, Spain
,
Ophthalmology, Alicante General University Hospital, Alicante, Spain
› Author Affiliations

Introduction

Glaucoma disease is not an isolated clinical entity. It represents a collection of multiple disorders that will indeed result in an optic neuropathy involving anatomical and functional impairment of the optic disc and visual field loss [1]. According to the mechanism of damage, this medical condition is classified as open-angle and closed-angle glaucoma and subclassified in idiopathic/primary, or secondary glaucoma if the underlying cause is identified [2]. Secondary acute angle-closure glaucoma (AACG) induced by drugs usually occurs in patients with anatomical susceptibility, short axial length, shallow anterior chamber, anteriorly located lens, and others, and there are two main mechanisms involved in its development: the pupillary block due to pharmacologic mydriasis and ciliochoroidal effusion due to the disruption of the blood-ocular barrier system [3]. Several treatments commonly used in clinical practice, and even some glaucoma medications such as latanoprost [4] and acetazolamide [3], [5], have been associated with AACG as a side effect. In the same vein, AACG can also be triggered by consumption of psychotropic substances, including amphetamines and cocaine.



Publication History

Received: 30 December 2020

Accepted: 06 February 2021

Publication Date:
14 April 2021 (online)

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany