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Z Gastroenterol 2021; 59(04): 336-344
DOI: 10.1055/a-1374-4192
Übersicht

Potenzial des Ultraschalls bei allogener Stammzelltransplantation und transplantationsassoziierten Komplikationen

Potential of ultrasound in allogeneic stem cell transplantation and transplant-related complications
Corinna Trenker
1   Klinik für Hämatologie, Onkologie und Immunologie, UKGM Marburg und Philipps-Universität Marburg
,
Christoph F. Dietrich 
3   Klinik Beauside, Departement für Allgemeine Innere Medizin, Hirslanden Bern
,
Stefan Klein
4   Universitätsklinikum Mannheim, III. Medizinische Klinik
,
Ehsan Safai Zadeh
2   Interdisziplinäres Ultraschallzentrum, UKGM Marburg
,
Kristina Sohlbach
1   Klinik für Hämatologie, Onkologie und Immunologie, UKGM Marburg und Philipps-Universität Marburg
,
Andreas Neubauer
1   Klinik für Hämatologie, Onkologie und Immunologie, UKGM Marburg und Philipps-Universität Marburg
,
Andreas Burchert
1   Klinik für Hämatologie, Onkologie und Immunologie, UKGM Marburg und Philipps-Universität Marburg
,
Christian Görg
2   Interdisziplinäres Ultraschallzentrum, UKGM Marburg
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Zusammenfassung

Die allogene hämatopoietische Stammzelltransplantation (allo-SZT) stellt eine komplexe Therapie mit vielen auch gastrointestinalen Nebenwirkungen und Komplikationen dar. Eine frühzeitige Diagnose und Behandlung von mit allo-SZT assoziierten Komplikationen ist daher von großer Bedeutung, um das Überleben dieser Patienten zu verbessern. Die Sonografie stellt eine schnell verfügbare Methode dar, die am Krankenbett durchgeführt werden kann. In den Händen eines sonografieerfahrenen Untersuchers können wichtige transplantationsbedingte Komplikationen sofort diagnostiziert oder ausgeschlossen werden. Das Ziel der Arbeit ist es, den diagnostischen und klinischen Wert von Ultraschall vor, während und nach der allo-SZT darzustellen.

Abstract

Allogeneic hematopoietic stem cell transplantation (HCT) is a complex therapeutic procedure causing significant morbidity and mortality, including the gastrointestinal tract. Early diagnosis and treatment of HCT-associated complications are, therefore, of utmost importance to improve overall HCT outcome. Sonography can be a powerful diagnostic tool and is easily accessible at the bedside of HCT patients. In the hands of a sonography-experienced physician, it allows for instant diagnosis and can also rule out several important transplant-associated complications. Here we review available evidence on the diagnostic and clinical value of ultrasound prior, during and after HCT.

Schlüsselwörter

GvHD - Guideline - allogene Stammzelltransplantation - Colitis - Splenomegalie - Komplikationen

Key words

GVHD - guideline - allogeneic stem cell transplantation - colitis - splenomegaly - complications


Publication History

Received: 17 October 2020

Accepted: 26 January 2021

Article published online:
25 February 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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