Aktuelle Ernährungsmedizin 2022; 47(03): 170-182
DOI: 10.1055/a-1354-5428
Übersicht

Bedeutung der Ernährungs- und Bewegungstherapie für den geriatrischen Patienten

Relevance of Nutritional and Physical Therapy in Geriatric Patients
Romana Lenzen-Großimlinghaus
1   Klinikum Ernst von Bergmann gGmbH, Klinik für Geriatrie
› Author Affiliations

Zusammenfassung

In Deutschland weisen in geriatrischen Abteilungen ca. 60% der Patienten ein Risiko für oder eine manifeste Mangelernährung auf. Nach Phasen der Unterernährung können ältere Menschen den Gewichtsverlust nicht ohne besondere therapeutische Unterstützung kompensieren. Je stärker die Mangelernährung im Alter ausgeprägt ist, umso mehr Muskelmasse geht verloren. Zum Wiederaufbau von Muskelmasse und -funktion benötigen alte Menschen significant mehr Energie und essenzielle Aminosäuren als junge. Der Energiebedarf zum Muskelaufbau steigt außerdem mit fallendem BMI. Bei krankheitsbedingter Immobilisierung verlieren ältere Menschen in 5 Tagen Bettruhe 4% ihrer Muskelmasse und 16% ihrer Muskelkraft. Daher muss es das Ziel einer medizinischen Behandlung geriatrischer Patienten sein, sowohl die Gesundung des Organismus zu erreichen als auch die Kraft und Funktion des muskuloskeletalen Systems zu erhalten. Dies wird im Alter nur durch gleichzeitige Bewegungs- und Ernährungstherapie erreicht. Bei Jungen reicht allein die Gabe von Proteinsupplementen zur Steigerung der muskulären Proteinsynthese nach Bettruhe, bei Alten müssen zusätzlich physiotherapeutische Maßnahmen erfolgen. Die Basis der funktionsorientierten Therapie ist die optimierte Ernährung des geriatrischen Patienten: Der tägliche Energiebedarf im Alter beträgt bei mäßiger Aktivität ca. 30 kcal/kg KG. Eine ausgeglichene Ernährung im Alter sollte 40–60% Kohlenhydrate, 15–20% Protein, 30–50% Fett umfassen, wobei der Proteinanteil durchaus höher sein kann und möglichst 1,5 g/kg KG betragen sollte. Störfaktoren der Ernährung im Alter sind vielfältig, müssen systematisch erfasst und multimodal behandelt werden. In der Geriatrie steht für dieses kombinierte Therapiekonzept das multiprofessionelle Team zur Verfügung.

Abstract

In Germany, about 60% of geriatric patients are at risk of protein-malnutrition or suffer from manifest malnutrition. After a period of undernutrition, weight loss and muscular weakness cannot be compensated in the elderly without individual support. The more malnutrition is present, the more difficult is the process of recovery. In the elderly, increase in muscle mass and function requires more intake of energy and essential amino acids than in youth. This process is even aggravated by lower BMI. During disease-associated immobilisation, elderly patients loose about 4% of muscle mass and 16% of muscle strength after 5 days of bed rest. The aim of medical treatment in the elderly must include strategies of healing and stabilising the functional capacity. Interventions in geriatric patients must combine exercise and nutritional support simultaneously. Daily energy requirements in the elderly with mild activity are about 30 kcal/kg body weight. Carbohydrates should be given at an amount of 40–60 %, proteins of 15–20% and fat by 30–50 %. Daily intake of proteins should be 1.5 g/kg body weight. Multidimensional factors which contribute to manifest malnutrition in the elderly should be systematically determined and – as far as possible – be modified by a multiprofessional geriatric team.



Publication History

Article published online:
14 June 2022

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  • Literatur

  • 1 Davidovic M, Erceg P, Trailov D. et al. The privilege to be old – Review. Gerontology 2003; 49: 335-339
  • 2 Lane N. A unifying view of ageing and disease: the double-agent theory. J Theor Biol 2003; 225: 531-540
  • 3 Tan BL, Norhaizan ME. Carotenoids: How effective are they to Prevent Age-related Diseases?. Molecules 2019; 24: 1801 DOI: 10.3390/molecules24091801.
  • 4 Cawthon RM, Smith KR, O’Brien E. et al. Association between telomere length in blood and mortality in people aged 60 years or older. Lancet 2003; 361: 393-395
  • 5 Cherkas LF, Hunkin JL, Kato BS. et al. The Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length. Arch Intern Med 2008; 168: 154-158
  • 6 Werner CM, Hecksteden A, Morsch A. et al. Differential effects of endurance, interval and resistance training on telomerase activity and telomere length in a randomized, controlled study. European Heart Journal 2019; 40: 34-46 DOI: 10.1093/eurheartj/ehy585.
  • 7 Dimauro I, Scalabrin M, Fantini C. et al. Resistance training and redox homeostasis: Correlation with age-associated genomic changes. Redox Biology 2016; 10: 34-44 DOI: 10.1016/j.redox.2016.09.008.
  • 8 Graf C, Beneke R, Bloch W. Recommendations for promoting physical activity for children and adolescents in Germany. A consensus statement. Obesity Facts 2014; 7: 178-190
  • 9 Hupin D, Roche F, Gremeaux V. et al. Even a low-dose of moderateto vigorous physical activity reduces mortality by 22 % in adults aged>60 years: a systematic review and meta-analysis. Br J Sports Med 2015; 49: 1262-1267 DOI: 10.1136/bjsports-2014-094306.
  • 10 Muscari A, Bianchi G, Forti P. et al. Physical Activity and other Determinants of Survival in the Oldest Adults. J Am Ger Soc 2016; 65: 402-406 DOI: 10.1110/jgs.14569.
  • 11 Krug S, Jordan S, Mensink GBM. et al. Körperliche Aktivität. Ergebnisse der Studie zur Gesundheit Erwachsener in Deutschland (DEGS1). Bundesgesundheitsbl 2013; 56: 765-771
  • 12 Statistisches Bundesamt Deutschland. Sterbetafeln 2017/2019. https://www.destatis.de/DE/Themen/Gesellschaft-Umwelt/Bevoelkerung/Sterbefaelle-Lebenserwartung/Publikationen/(letzter Zugriff 1.11.2020)
  • 13 Taroni B, Büla W, Darioli C. Statins in older patients: limits to prescription?. Rev Med Suisse 2005; 1: 2512-2514
  • 14 Pirlich M, Schütz T, Norman C. et al. The German hospital malnutrition study. Clin Nutr 2006; 25: 563-572 DOI: 10.1016/j.clnu.2006.03.005.
  • 15 Volkert D, Kiesswetter E, Visser M. DoMAP – ein Determinanten- Modell zur Entstehung von Mangelernährung im Alter. Ernährungs Umschau 2020; 67: M530-M535 DOI: 10.4455/eu.2020.047.
  • 16 Correia MI, Waitzberg DL. The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis. Clin Nutr 2003; 22: 235-239
  • 17 Cruz-Jentoft AJ, Landi F, Schneider SM. et al. Prevalence of and interventions for sarcopenia in ageing adults: a systematic review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS). Age Ageing 2014; 43: 748-759 DOI: 10.1093/ageing/afu115.
  • 18 Cruz-Jentoft AJ, Bahat G, Bauer J. et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 2019; 48: 16-31
  • 19 Iannuzzi-Sucich M, Prestwood KM, Kenny AM. Prevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women. J Gerontol A Biol Sci Med Sci 2002; 57: 772-777
  • 20 Uemura K, Doi T, Lee S. et al. Sarcopenia and Low Serum Albumin Level Synergistically increase ther Risk of Incident Disability in Older Adults. JAMDA 2019; 20: 90-93 DOI: 10.1016/j.jamda.2018.06.011.
  • 21 Nair KS. Aging muscle. Am J Clin Nutr 2005; 81: 953-963
  • 22 Drummond MJ, Dickinson JM, Fry CS. et al. Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults. Am J Physiol Endocrinol Metab 2012; 302: E1113-E1122 DOI: 10.1152/ajpendo.00603.2011.
  • 23 Delmonico MJ, Harris TB, Visser M. et al. Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr 2009; 90: 1579-1585 DOI: 10.3945/ajcn.. 2009.28047
  • 24 Wilkinson DJ, Piasecki M, Atherton PJ. et al. The Age-Related Loss of Skeletal Muscle Mass and Function: Measurement and Physiology of Muscle Fibre Atrophy and Muscle Fibre Loss in Humans. Ageing Research Reviews 2018; 47: 123-132 DOI: 10.1016/j.arr.2018.07.005.
  • 25 Evans WJ. Skeletal muscle loss: cachexia, sarcopenia, and inactivity. Am J clin Nutr 2010; 91: 1123S-1127S
  • 26 Kouw IWK. One Week of Hospitalization Following Elective Hip Surgery Induces Substantial Muscle Atrophy in Older Patients. JAMDA 2019; 20: 35-42 DOI: 10.1016/j.jamda.2018.06.018.
  • 27 Kortebein P, Ferrando A, Lombeida J. et al. Effect of 10 days of bed rest on skeletal muscle in healthy older adults. JAMA 2007; 297: 1769-1774
  • 28 Reid KF, Fielding RA. Skeletal muscle power: A critical determinant of physical functioning in older adults. Exerc Sport Sci Rev 2012; 40: 4-12
  • 29 Fox KM, Magaziner J, Hawkes WG. et al. Loss of bone density and lean body mass after hip fracture. Osteoporos Int 2000; 11: 31-35
  • 30 Kojima G. Frailty as a predictor of fractures among community-dwelling older people: A systematic review and meta-analysis. Bone 2016; 90: 116-122 DOI: 10.1016/j.bone.2016.06.009.
  • 31 Dickinson JM, Rasmussen BB. Essential amino acid sensing, signaling, and transport in the regulation of human muscle protein metabolism. Curr Opin Clin Nutr Metab Care 2011; 14: 83-88 DOI: 10.1097/mco.0b013e3283406f3e.
  • 32 Paddon-Jones D, Campbell WW, Jacques PF. et al. Protein and healthy aging. Am J Clin Nutr 2015; 101: 1339S-1345S DOI: 10.3945/ajcn.114.084061.
  • 33 Norman K, Richard C, Lochs H. et al. Prognostic impact of diseaserelated malnutrition. Clin Nutr 2008; 27: 5-15
  • 34 Gaillard C, Alix E, Salle A. et al. Energy requirements in frail elderly people: a review of the literature. Clin Nutr 2007; 26: 16-24
  • 35 Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung et al.. Referenzwerte für die Nährstoffzufuhr. 2. Aufl. Neustadt an der Weinstraße: Umschau Buchverlag; 2015
  • 36 EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on dietary reference values for energy. EFSA Journal 2013; 11 3005 1-112
  • 37 Roberts SB, Dallal GE. Energy requirements and aging. Public Health Nutr 2005; 8: 1028-1036
  • 38 Blanc S, Schoeller DA, Bauer D. et al. Energy requirements in the eighth decade of life. Am J Clin Nutr 2004; 79: 303-310
  • 39 Manini TM, Everhart JE, Anton SD. et al. Activity energy expenditure and change in body composition in late life. Am J Clin Nutr 2009; 90: 1336-1342
  • 40 Aubry E, Aeberhard C, Leuenberger MS. et al. Refeeding-Syndrom: Ein konsensusbasierter Algorithmus für stationäre Patienten. Aktuel Ernahrungsmed 2019; 44: 33-42 DOI: 10.1055/a-0604-7900.
  • 41 Deutsche Gesellschaft für Ernährung e. V.. DGE-Position Richtwerte für die Energiezufuhr aus Kohlenhydraten und Fett. Bonn: 2011
  • 42 Deutz NE, Bauer JM, Barrazoni R. et al. Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN expert group. Clin Nutr 2014; 33: 929-936
  • 43 EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on dietary reference values for protein. EFSA Journal 2012; 10 2557 1-66
  • 44 Katsanos CS, Kobayashi H, Sheffield-Moore M. et al. Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids. Am J Clin Nutr 2005; 82: 1065-1073
  • 45 Beasley JM, LaCroix AZ, Neuhouser ML. et al. Protein intake and incident frailty in the Women’s Health Initiative observational study. J Am Geriatr Soc 2010; 58: 1063-1071
  • 46 Houston DK, Nicklas BJ, Ding JZ. et al. Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr 2008; 87: 150-155
  • 47 Bauer J, Biolo G, Cederholm T. et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group. J Am Med Dir Assoc 2013; 14: 542-559
  • 48 Deutz NE, Bauer JM, Barazzoni R. et al. Protein intake and exercise for optimal muscle function with aging: recommendations from the ESPEN Expert Group. Clin Nutr 2014; 33: 929-936
  • 49 Rizzoli R, Stevenson JC, Bauer JM. et al. The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: a consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas 2014; 79: 122-132
  • 50 Norman K, Kirchner H, Freudenreich J. et al. Three month intervention with protein and energy rich supplements improve muscle function and quality of life in malnourished patients with non-neoplastic gastrointestinal disease – A randomised controlled trial. Clin Nutr 2008; 27: 48-56
  • 51 Paddon-Jones D, Rasmussen BB. Dietary protein recommendations and the prevention of sarcopenia. Curr Opin Clin Nutr Metab Care 2009; 12: 86-90
  • 52 Churchward-Venne TA, Burd NA, Phillips SM. Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism. Nutr Metab (Lond) 2012; 9: 40
  • 53 World Health Organisation. Energy and protein requirements. Report of a Joint FAO/WHO/UNU Expert Consultation. Technical Report Series 724. Geneva: World Health Organisation; 1985
  • 54 Peterson MD, Sen A, Gordon PM. Influence of resistance exercise on lean body mass in aging adults: a meta-analysis. Med Sci Sports Exerc 2011; 43: 249-258
  • 55 Papa EV, Dong X, Hassan M. Resistance training for activity limitations in older adults with skeletal muscle function deficits: A systematic review. Clin Interv Aging 2017; 12: 955-961
  • 56 Fiatarone MA, Marks EC, Ryan ND. et al. High-intensity strength training in nonagenarians. Effects on skeletal muscle. JAMA 1990; 263: 3029-3034
  • 57 Fiatarone-Singh MA, Ding W, Manfredi TJ. et al. Insulin-like growth factor 1 in skeletal muscle after exercise in frail elders. Journal of Applied Physiology Endocrinology and Metabolism 1999; 277: E135-E143
  • 58 Wagner A, Mühlenhoff S, Sebastian D. Krafttraining im Radsport. Methoden und Übungen zur Leistungssteigerung und Prävention. München: Urban & Fischer bei Elsevier; 2010. www.krafttraining-imradsport de
  • 59 Mayer F, Scharhag-Rosenberger F, Carlson A. et al. The intensity and effects of strength training in the elderly. Dtsch Arztebl Int 2011; 108: 359-364
  • 60 Tinetti ME. Preventing falls in elderly persons. New Engl J Med 2003; 348: 42-49
  • 61 Landi F, Liperoti R, Russo A. et al. Sarcopenia as a risk factor for falls in elderly individuals: Results from the ilSIRENTE study. Clin Nutr 2012; 31: 652-658
  • 62 Fiatarone MA, O’Neill EF, Ryan ND. et al. Exercise Training and Nutritional Supplementation for physical Frailty in very elderly People. New Engl J Med 1994; 330: 1769-1775 DOI: 10.1056/NEJM199406233302501.
  • 63 Bauer JM, Verlann S, Bautmans I. et al. Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double- Blind, Placebo-Controlled Trial. JAMDA 2015; 16: 740-747 DOI: 10.1016/j.jamda.2015.05.021.
  • 64 Bo Y, Liu C, Ji Z. et al. A high whey protein, vitamin D and E supplement preserves muscle mass, strength, and quality of life in sarcopenic older adults: A double-blind randomized controlled trial. Clin Nutr J 2019; 38: 159-164 DOI: 10.1016/j.clnu.2017.12.020.
  • 65 Tanner RE, Brunker LB, Agergaard J. et al. Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation. J Physiol 2015; 593: 4259-4273 DOI: 10.1113/JP270699.
  • 66 Bundesverband Geriatrie e.V.. Hrsg. Weissbuch Geriatrie. Stuttgart: Kohlhammer; 2010
  • 67 Kiesswetter E. Mangelernährung im Alter – Screening und Assessment. Dtsch med Wochenschr 2020; 145: 1299-1305 DOI: 10.1055/a-0986-2850.
  • 68 Guigoz Y, Lauque S, Vellas BJ. Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment. Clin Geriatr Med 2002; 18: 737-757
  • 69 Kaiser MJ, Bauer JM, Ramsch C. et al. Validation of the Mini Nutritional Assessment short-form (MNA-SF): a practical tool for identification of nutritional status. J Nutr Health Aging 2009; 13: 782-788
  • 70 Volkert D, Bauer JM, Frühwald T. et al. Leitlinie der Deutschen Gesellschaft für Ernährungsmedizin (DGEM) in Zusammenarbeit mit der GESKES, der AKE und der DGG. Klinische Ernährung in der Geriatrie.Aktuel Ernahrungsmed 2013; 38: e1-e48
  • 71 Kondrup J, Allison SP, Elia M. et al. ESPEN guidelines for nutrition screening 2002. Clin Nutr 2003; 22: 415-421
  • 72 British Association of Parenteral and Enteral Nutrition (BAPEN). Malnutrition Universal Screening Tool (MUST) http://www.bapen.org.uk/images/pdfs/must/german/must-toolkit.pdf(eingesehen am 29.04.2015)
  • 73 Kondrup J, Rasmussen HH, Hamberg O. et al. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr 2003; 22: 321-336
  • 74 Detsky AS, McLaughlin JR, Baker JP. et al. What is subjective global assessment of nutritional status?. JPEN J Parent Enteral Nutr 1987; 11: 8-13
  • 75 Haß U, Schwejda-Güttes S, Kuhn KS. et al. Einsatz und Nutzen funktioneller Parameter als Endpunkte in klinischen Ernährungsstudien. Aktuel Ernahrungsmed 2018; 43: 162-172 DOI: 10.1055/a-0603-2891.
  • 76 Alencar MA, Dias JM, Figueiredo LC. et al. Handgrip strength in elderly with dementia: study of reliability. Rev Bras Fisioter 2012; 16: 510-514
  • 77 Payette H, Hanusaik N, Boutier V. et al. Muscle strength and functional mobility in relation to lean body mass in free-living frail elderly women. Eur J Clin Nutr 1998; 52: 45-53 DOI: 10.1038/sj.ejcn.1600513.
  • 78 Parry SM, Berney S, Granger CL. et al. A new two-tier strength assessment approach to the diagnosis of weakness in intensive care: an observational study. Crit Care 2015; 19: 52 DOI: 10.1186/s13054-015-0780-5.
  • 79 Trutschnigg B, Kilgour RD, Reinglas J. et al. Precision and reliability of strength (Jamar vs. Biodex handgrip) and body composition (dualenergy X-ray absorptiometry vs. bioimpedance analysis) measurements in advanced cancer patients. Appl Physiol Nutr Metab 2008; 33: 1232-1239 DOI: 10.1139/H08-122.
  • 80 Legrand D, Vaes B, Matheï C. et al. Muscle strength and physical performance as predictors of mortality, hospitalization, and disability in the oldest old. J Am Geriatr Soc 2014; 62: 1030-1038 DOI: 10.1016/j.archger.2013.06.003.
  • 81 Harda ND. et al. An evaluation of three self-report physical activity instruments for older adults. Med Sci Sports Exerc 2001; 33: 96 DOI: 10.1097/00005768-200106000-000162-970.
  • 82 ATS (American Thoracic Society). statement: guidelines for the sixminute walk test. Am J Respir Crit Care Med 2002; 166: 111-117 DOI: 10.1164/rccm.166/1/111.
  • 83 Podsiadlo D. The „Timed Up-and Go“: a test of basic funktional mobility for frail elderly persons. J Am Geriatr Soc 1991; 39: 142-148
  • 84 Mathias S, Nayak US, Isaacs B. Balance in elderly patients: the “get-up and go” test. Arch Phys Med Rehabil 1986; 67: 387-389
  • 85 Guralnik JM. et al. A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 1994; 49: M85-M94 DOI: 10.1186/s12916-016-0763-7.
  • 86 Mahoney FI, Barthel DW. Functional Evaluation: The Barthel Index. Md State Med J 1965; 14: 61-65
  • 87 Denkinger MD, Weyerhäuser K, Nikolaus T. et al. Reliability of the abbreviated version of the Late Life Function and Disability Instrument – a meaningful and feasible tool to assess physical function and disability in the elderly. Z Gerontol Geriatr 2009; 42: 28-38 DOI: 10.1007/s00391-008-0550-y.
  • 88 Potter JM, Roberts MA, McColl JH. et al. Protein energy supplements in unwell elderly patients – a randomized controlled trial. JPEN J Parenter Enteral Nutr 2001; 25: 323-329 DOI: 10.1177/0148607101025006323.
  • 89 Izawa S, Enoki H, Hirakawa Y. et al. The longitudinal change in anthropometric measurements and the association with physical function decline in Japanese community-dwelling frail elderly. Br J Nutr 2010; 103: 289-294 DOI: 10.1017/S0007114509991723.
  • 90 Martinez-Velilla N, Casas-Herrero A, Zambom-Ferraresi F. et al. Effect of Exercise Intervention on functional Decline in Very Elderly Patients during acute hospitalization. A Randomized Trial. JAMA Intern Med 2019; 179: 28-36 DOI: 10.1001/jamainternmed.2018.4869.
  • 91 Schuetz P, Fehr R, Baechli V. et al. Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial. Lancet 2019; 393: 2312-2321 DOI: 10.1016/S0140-6736(18)32856-3.
  • 92 Müller MC, Uedelhofen KW, Wiedemann UCH. CEPTON-Studie: Mangelernährung in Deutschland. Erlangen: Bressler Druck; 2007
  • 93 Chr Löser. Malnutrition in hospital – the clinical and economic implications. Dtsch Arztebl Int 2010; 107: 911-917 DOI: 10.3238/arztebl.. 2010.0911
  • 94 Riley K, Suela Sulo S, Dabbous F. et al. Reducing Hospitalizations and Costs: A Home Health Nutrition-Focused Quality Improvement Program. JPEN J Parenter Enteral Nutr 2020; 44: 58-68 DOI: 10.1002/jpen.1606.