Drug Res (Stuttg) 2021; 71(05): 233-242
DOI: 10.1055/a-1334-4101
Review

A Panoramic Review on Lepidium sativum L. Bioactives as Prospective Therapeutics

Asad Ahmad
1  Faculty of Pharmacy, Integral University, Dasauli, Kursi Road, Lucknow, Uttar Pradesh, India
,
Rabia Nabi
3  Department of Bioscience, Integral University, Dasauli, Kursi Road, Lucknow, Uttar Pradesh, India
,
1  Faculty of Pharmacy, Integral University, Dasauli, Kursi Road, Lucknow, Uttar Pradesh, India
,
Iffat Zareen Ahmad
2  Department of Bioengineering, Integral University, Dasauli, Kursi Road, Lucknow, Uttar Pradesh, India
› Author Affiliations

Abstract

Background Lepidium sativum (L. sativum), an annual herb belonging to family Brassicaceae is commonly known as Garden cress of Egyptian origin but now a day’s cultivated worldwide. The plant material and its constituents are used in various traditional and folk medicines for the treatment of various liver diseases and other ailments.

Objective This review aims to gather comprehensive information on L. sativumʼs bioactive constituents, and itʼs antioxidant, hepato-protective and anticancer activity.

Method Systematic exploration for research evidences were carried out using well-structured and focused review question and presented data in the tabular form for readers’ convenience.

Results The comprehensive literature survey was conducted, and we found that specific studies on L. Sativum and its bioactive compounds had been carried out to date. We explored the unique and selective effect of L. Sativum and its bioactive constituents to combat oxidative stress and hepatic carcinoma.

Conclusion The present article appraised that L. sativum extract has a potential therapeutic effect against liver toxicity and hepato-carcinoma. [Graphical Abstract].

Supplementary Material



Publication History

Received: 17 August 2020

Accepted: 07 December 2020

Publication Date:
30 December 2020 (online)

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany