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Endoscopy 2021; 53(09): 914-919
DOI: 10.1055/a-1333-2120
Innovations and brief communications

Screening for upper gastrointestinal cancers with magnetically controlled capsule gastroscopy: a feasibility study

Zhen Li   *
1   Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China
,
Jing Liu   *
1   Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China
,
Chao-Ran Ji
1   Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China
,
Fei-Xue Chen
1   Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China
,
Fu-Guo Liu
2   Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
,
Jian Ge
3   Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
,
Yong Chen
3   Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
,
Xue-Guo Sun
2   Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
,
Yan-Yan Lu
2   Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China
,
Gui-Hua Cheng
4   ANKON Medical Technologies (Shanghai) Co., Ltd., Shanghai, China
,
Jie Zhang
4   ANKON Medical Technologies (Shanghai) Co., Ltd., Shanghai, China
,
Peng Li
5   Department of Pathology, Qilu Hospital of Shandong University, Jinan, Shandong, China
,
Ji-Yong Liu
3   Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
,
Chong-Mei Yang
3   Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
,
Xiu-Li Zuo
1   Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China
,
Yan-Qing Li
1   Department of Gastroenterology, Laboratory of Translational Gastroenterology, and Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Jinan, Shandong, China
› Author AffiliationsAnkon LW Fund (2018)
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Referred to by:

Author commentary on Zhen Li et al.Endoscopy 2021; 53(09): v43-v43
DOI: 10.1055/a-1347-8714

Referred to by:

Magnetically assisted capsule endoscopy as a mass screening tool: is it ready for prime time?Endoscopy 2021; 53(09): 920-921
DOI: 10.1055/a-1348-1219

Abstract

Background The medical consortium is an intensive and disease-specific association that integrates tertiary public hospitals and medical examination centers in China. We aimed to evaluate the feasibility of the medical consortium for screening upper gastrointestinal (GI) cancers (MCSC) by magnetically controlled capsule gastroscopy (MCCG).

Methods 6627 asymptomatic subjects underwent MCCG as part of health check-ups in the MCSC between March and November 2018. Relevant clinical data were collected and analyzed.

Results The MCSC detected 32 patients with upper GI cancer (0.48 %) confirmed by pathology. The detection rate of early gastric cancer was 16.67 % (4 /24). Gastric polyps, ulcers, and submucosal tumors were found in 15.54 %, 3.76 %, and 3.17 % of subjects, respectively. The whole GI preparation and operation process were well tolerated.

Conclusions The MCSC was a feasible model for upper GI cancer screening, especially for asymptomatic subjects. Further prospective studies with better operational quality control are warranted.

* Contributed equally to this work


Table 1s–3s, Fig. 1s, 2s



Publication History

Received: 02 March 2020

Accepted: 20 November 2020

Article published online:
12 February 2021

© 2021. Thieme. All rights reserved.

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