Author commentary on Noam Peleg et al.

Noam Peleg et al. Neutrophil to lymphocyte ratio and risk of neoplastic progression in patients with Barrett’s esophagus

An analysis in 324 individuals with Barrett’s esophagus showed that a simple inflammation marker, the peripheral blood neutrophil to lymphocyte ratio (NLR), was predictive of progression to neoplasia. In particular, an NLR above 2.4 was associated with a 3-fold increase in progression to high grade dysplasia or adenocarcinoma during follow-up. This finding was consistent even in patients with nondysplastic Barrett’s esophagus at baseline.

Publication History

Article published online:
27 July 2021