Horm Metab Res 2020; 52(11): 775-783
DOI: 10.1055/a-1243-5462
Review

Are Adequate Vitamin D Levels Helpful in Fighting COVID-19? A Look at the Evidence

1   Woodlands Health Campus, National Healthcare Group, Singapore
,
Koh Huilin
1   Woodlands Health Campus, National Healthcare Group, Singapore
,
Sanda Cho
2   Warrington and Halton Hospitals NHS Foundation Trust, Warrington, United Kingdom
,
Veeraraghavan Meyyur Aravamudan
1   Woodlands Health Campus, National Healthcare Group, Singapore
,
Jaime Hui Xian Lin
1   Woodlands Health Campus, National Healthcare Group, Singapore
› Author Affiliations

Abstract

COVID-19 is a global pandemic with high mortality in vulnerable groups. Given the current lack of definitive treatment or vaccine that significantly reduces mortality rate, governments, researchers and healthcare providers are racing to find possible solutions to the crisis. Vitamin D and its analogues have been previously studied for their non-skeletal benefits. In particular, questions regarding their role in the modulation of immunity have re-surfaced, in view of possible epidemiological links observed between COVID-19 and vitamin D levels in selected populations. In this review, we highlight potential mechanisms and summarise the evidence for and against the potential role of vitamin D supplementation in our fight against COVID-19.



Publication History

Received: 27 May 2020

Accepted after revision: 14 August 2020

Publication Date:
17 September 2020 (online)

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