CC BY-NC-ND 4.0 · Endosc Int Open 2020; 08(11): E1681-E1682
DOI: 10.1055/a-1236-3540

EUS-guided choledocoduodenostomy and gastroenterostomy to palliate simultaneous biliary and duodenal obstruction due to pancreatic cancer

Michael Lajin
Sharp Grossmont Hospital, La Mesa, California, United States
› Author Affiliations

Endoscopic management of simultaneous biliary and duodenal malignant obstructions can be challenging. Traditionally, duodenal and biliary stentings have been used [1] [2].

We review the case of a 45-year-old male who presented with jaundice and weight loss. Abdominal computed tomography (CT) showed a 3.4-cm mass at the head of the pancreas resulting in biliary obstruction without liver metastasis ([Video 1]).

Video 1 EUS-guided Choledochoduodenostomy and gastroenterostomy to palliate biliary and duodenal obstruction due to pancreatic cancer.


Endoscopic ultrasound (EUS)-guided fine-needle aspiration was consistent with locally advanced pancreatic adenocarcinoma. Endoscopic retrograde cholangiopancreatography could not be performed due to severe duodenal stricture proximal to the ampulla.

Using EUS, the common bile duct (2.6 cm) was punctured from the duodenal bulb with a 19G needle. Cholangiogram was obtained and a wire was passed ([Fig. 1]). Hot Axios (1-cm diameter) was deployed followed by a 3-cm, 7F double pigtail stent ([Fig. 2]).

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Fig. 1 EUS-guided cholangiogram.
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Fig. 2 Choledochoduodenostomy after deployment of LAMS and double pigtail stent.

Six days later, the patient started vomiting. An upper gastrointestinal imaging series demonstrated a duodenal stricture with reflux of contrast through Axios to the biliary tree.

A pediatric endoscope was able to traverse the duodenal stricture. It was used to distend the targeted jejunal loop with contrast and methylene blue. An echoendoscope (introduced on the side of the pediatric endoscope) was able to identify the targeted jejunal loop ([Fig. 3]). A 2-cm-diameter Hot Axios was deployed. The stent was dilated to 2 cm ([Fig. 4], [Fig. 5]).

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Fig. 3 EUS image of target jejunal loop.
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Fig. 4 Gastroenterostomy after deployment and dilation of LAMS. 
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Fig. 5 X-ray image of choledochoduodenostomy and gastroenterostomy stents.

The procedure was uneventful.

CT demonstrated a successful gastroenterostomy ([Fig. 6]).

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Fig. 6 CT image of choledochoduodenostomy and gastroenterostomy stents.

In conclusion, EUS-guided choledochoduodenostomy/gastroenterostomy can be considered as an alternative treatment for duodenal/biliary stenting in patients with combined biliary/duodenal malignant strictures types I & II [1]. This technique allows for easier future access to the biliary tree. In addition, duodenal stenting has a higher rate of reintervention than gastroenterostomy [3].

Publication History

Publication Date:
22 October 2020 (online)

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (

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