CC BY-NC-ND 4.0 · Endosc Int Open 2020; 08(11): E1584-E1594
DOI: 10.1055/a-1236-3007
Original article

Accuracy of convolutional neural network-based artificial intelligence in diagnosis of gastrointestinal lesions based on endoscopic images: A systematic review and meta-analysis

Babu P. Mohan
1  Gastroenterology & Hepatology, University of Utah Health, Salt Lake City, Utah, United States
Shahab R. Khan
2  Gastroenterology, Rush University Medical Center, Chicago, Illinois, United States
Lena L. Kassab
3  Internal Medicine, Mayo Clinic, Rochester, Minnesota, United States
Suresh Ponnada
4  Internal Medicine, Roanoke Medical Center, Roanoke, Virginia, United States
Parambir S. Dulai
5  Gastroenterology and Hepatology, University of California, San Diego, California, United States
Gursimran S. Kochhar
6  Division of Gastroenterology and Hepatology, Allegheny Health Network, Pittsburgh, Pennsylvania, United States
› Author Affiliations


Background and study aims Recently, a growing body of evidence has been amassed on evaluation of artificial intelligence (AI) known as deep learning in computer-aided diagnosis of gastrointestinal lesions by means of convolutional neural networks (CNN). We conducted this meta-analysis to study pooled rates of performance for CNN-based AI in diagnosis of gastrointestinal neoplasia from endoscopic images.

Methods Multiple databases were searched (from inception to November 2019) and studies that reported on the performance of AI by means of CNN in the diagnosis of gastrointestinal tumors were selected. A random effects model was used and pooled accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated. Pooled rates were categorized based on the gastrointestinal location of lesion (esophagus, stomach and colorectum).

Results Nineteen studies were included in our final analysis. The pooled accuracy of CNN in esophageal neoplasia was 87.2 % (76–93.6) and NPV was 92.1 % (85.9–95.7); the accuracy in lesions of stomach was 85.8 % (79.8–90.3) and NPV was 92.1 % (85.9–95.7); and in colorectal neoplasia the accuracy was 89.9 % (82–94.7) and NPV was 94.3 % (86.4–97.7).

Conclusions Based on our meta-analysis, CNN-based AI achieved high accuracy in diagnosis of lesions in esophagus, stomach, and colorectum.

Supplementary material

Publication History

Received: 22 April 2020

Accepted: 08 July 2020

Publication Date:
22 October 2020 (online)

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