Drug Res (Stuttg) 2020; 70(10): 448-454
DOI: 10.1055/a-1224-3625
Review

Current Pharmacological Trends on Myricetin

Gudiya Gupta
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Mohd Aftab Siddiqui
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Mohd Muazzam Khan
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Mohd Ajmal
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Rabiya Ahsan
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Md Azizur Rahaman
2   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Integral University, Lucknow, India
,
Md Afroz Ahmad
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Md Arshad
3   Department of Zoology, Aligarh Muslim University, Aligarh, India
,
Mohammad Khushtar
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
› Author Affiliations

Abstract

Myricetin is a member of the group of flavonoids called flavonols. Myricetin is obtained from various fruit, vegetables, tea, berries and red wine. Myricetin is characterized by the pysrogallol B-ring, and the more hydroxylated structure is known to be capable for its increased biological properties compared with other flavonols. Myricetin is produced by the Myricaceae, Anacardiaceae, Polygonaceae, Pinaceae and Primulacea families. It is soluble in organic solvent such as ethanol, DMSO (dimethyl sulfoxide), and dimethyl formamide (DMF). It is sparingly soluble in aqueous buffers. Myricetin shows its various pharmacological activities including antioxidant, anti-amyloidogenic, antibacterial, antiviral, antidiabetic, anticancer, anti-inflammatory, anti-epileptic and anti-ulcer. This review article focuses on pharmacological effects of Myricetin on different diseases such as osteoporotic disorder, anti-inflammatory disorder, alzheimer’s disease, anti-epileptic, cancer, cardiac disorder, diabetic metabolic disorder, hepatoprotective disorder and gastro protective disorder.



Publication History

Received: 10 April 2020

Accepted: 20 July 2020

Article published online:
02 September 2020

© 2020. Thieme. All rights reserved.

© Georg Thieme Verlag KG
Stuttgart · New York

 
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