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CC BY-NC-ND 4.0 · Endosc Int Open 2020; 08(10): E1315-E1320
DOI: 10.1055/a-1221-4578
Review

Tissue acquisition and pancreatic masses: Which needle and which acquisition technique should be used?

Benedetto Mangiavillano
1   Gastrointestinal Endoscopy Unit – Humanitas Mater Domini – Castellanza (VA), Italy
2   Humamitas University
,
Leonardo Sosa-Valencia
3   Ihu Strasbourg - Institute of Guided Image Surgery, Strasbourg, France
,
Pierre Deprez
4   Department of Hepato-Gastroenterology, Cliniques universitaires Saint-Luc,
,
Pierre Eisendrath
5   Endoscopy Unit Hopital Erasme, Brussels, Belgium
,
Carlos Robles-Medranda
6   Instituto Ecuatoriano de Enfermedades Digestivas (IECED), Guayaquil, Ecuador
,
Leonardo H. Eusebi
7   Endoscopy Unit, Department of Medical and Surgical Sciences, Sant’Orsola University Hospital, Bologna, Italy
,
Milena Di Leo
8   Digestive Endoscopy Unit, Humanitas Clinical and Research Center, Rozzano (MI), Italy.
,
Francesco Auriemma
1   Gastrointestinal Endoscopy Unit – Humanitas Mater Domini – Castellanza (VA), Italy
,
Mario Bianchetti
1   Gastrointestinal Endoscopy Unit – Humanitas Mater Domini – Castellanza (VA), Italy
,
Andrea Anderloni
8   Digestive Endoscopy Unit, Humanitas Clinical and Research Center, Rozzano (MI), Italy.
,
Silvia Carrara
8   Digestive Endoscopy Unit, Humanitas Clinical and Research Center, Rozzano (MI), Italy.
,
Alessandro Repici
2   Humamitas University
8   Digestive Endoscopy Unit, Humanitas Clinical and Research Center, Rozzano (MI), Italy.
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Abstract

Background and study aims Pancreatic cancer represents the fourth most common cause of cancer-related deaths in Western countries and the need of a low-risk investigation to obtain an accurate histopathological diagnosis has become increasingly pressing. Endoscopic ultrasonography (EUS) with fine-needle aspiration (FNA) is the standard method for obtaining samples from pancreatic masses. In recent years, there has been an increasing need to obtain histological specimens during EUS procedures, rather than cytological ones, to guide oncological treatment options, leading to the so-call “FNB concept.” Different needles have been developed for fine-needle biopsy (FNB) in recent years, enabling acquisition of larger specimens on which to perform histological and molecular analyses. The aim of this narrative review was to assess the role of EUS-guided FNA and FNB in patients with pancreatic masses, and to identify which needle and which acquisition technique should be used to improve tissue acquisition.



Publication History

Received: 01 April 2020

Accepted: 17 June 2020

Article published online:
22 September 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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