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Drug Res (Stuttg) 2020; 70(10): 441-447
DOI: 10.1055/a-1207-9469
Review

A Comprehensive Review on Physiological Effects of Curcumin

Rabiya Ahsan
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Md Arshad
2   Department of Zoology, Lucknow University, Lucknow, India
3   Department of Zoology, Aligarh Muslim University, Aligarh, India
,
Mohammad Khushtar
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Mohd Afroz Ahmad
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Mohammad Muazzam
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Md Sohel Akhter
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Gudiya Gupta
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
,
Mohd Muzahid
1   Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India
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Abstract

Turmeric (Curcuma longa Linn) is an herbal medicine which is traditionally used as a spice, food colouring or flavouring agent and widely used for several diseases such as biliary disorders, cough, hepatic disorders, rheumatism, wound healing, sinusitis, diabetes, cardiac disorders and neurological disorder. It belongs to the Zingiberaceae family. Turmeric is a popular domicile remedy used in Indian food, is mainly a native of south-east Asia, is widely cultivated in India, Sri Lanka, Indonesia, China, Jamaica , Peru, Haiti and Taiwan and it is very less expensive. Curcumin is the main principle of turmeric. Curcumin has shown various biological properties pre-clinically and clinically. Curcumin is a highly pleiotropic molecule which can be modulators of various intracellular signalling pathways that maintain cell growth. It has been reported as anti-inflammatory, anti-angiogenic, antioxidant, wound healing, anti-cancer, anti-Alzheimer and anti-arthritis and possesses an excellent safety profile. All previous review articles on curcumin have collected the biological/pharmacological activities but this review article summarises the most interesting in vitro and in vivo studies of curcumin on most running diseases around the whole world.

Key words

anti-inflammatory drugs - cardiovascular pharmacology - pharmacology - pulmonary & respiratory pharmacology - inflammation - cardiovascular diseases


Publication History

Received: 29 March 2020

Accepted: 22 June 2020

Article published online:
03 August 2020

© 2020. Thieme. All rights reserved.

© Georg Thieme Verlag KG
Stuttgart · New York

 

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