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Int J Sports Med 2021; 42(01): 3-18
DOI: 10.1055/a-1198-5496
Review

Mapping Robust Genetic Variants Associated with Exercise Responses

Javier Alvarez-Romero
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
,
Sarah Voisin
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
,
Nir Eynon
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
2   MCRI, Murdoch Childrens Research Institute, Parkville, Australia
,
Danielle Hiam 
1   Institute for Health and Sport, Victoria University, Melbourne, Australia
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Abstract

This review summarised robust and consistent genetic variants associated with aerobic-related and resistance-related phenotypes. In total we highlight 12 SNPs and 7 SNPs that are robustly associated with variance in aerobic-related and resistance-related phenotypes respectively. To date, there is very little literature ascribed to understanding the interplay between genes and environmental factors and the development of physiological traits. We discuss future directions, including large-scale exercise studies to elucidate the functional relevance of the discovered genomic markers. This approach will allow more rigour and reproducible research in the field of exercise genomics.

Key words

trainability - aerobic exercise - exercise genetics - resistance exercise - SNPs - genetic variants


Publikationsverlauf

Eingereicht: 24. Januar 2020

Angenommen: 01. Juni 2020

Artikel online veröffentlicht:
21. Juli 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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