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Hamostaseologie 2020; 40(04): 467-471
DOI: 10.1055/a-1181-0327
Review Article

Laboratory Assessment of Coagulation Factor XIII

Verena Schroeder
1   Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland
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Abstract

Laboratory diagnosis of congenital and acquired deficiencies of coagulation factor XIII (FXIII) can be challenging. Determination of FXIII function requires specific and sensitive assays which are not always available. This brief review article summarizes currently used FXIII assay methods, their principles and difficulties, and discusses the recommended diagnostic workup in case of a suspected FXIII deficiency. The article also briefly touches on experimental methods used in FXIII research.

Keywords

coagulation factor XIII - factor XIII assay - FXIII deficiency


Publikationsverlauf

Eingereicht: 15. April 2020

Angenommen: 18. Mai 2020

Artikel online veröffentlicht:
31. August 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Stuttgart · New York

 

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