Hamostaseologie 2020; 40(04): 467-471
DOI: 10.1055/a-1181-0327
Review Article

Laboratory Assessment of Coagulation Factor XIII

Verena Schroeder
1  Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland
› Author Affiliations


Laboratory diagnosis of congenital and acquired deficiencies of coagulation factor XIII (FXIII) can be challenging. Determination of FXIII function requires specific and sensitive assays which are not always available. This brief review article summarizes currently used FXIII assay methods, their principles and difficulties, and discusses the recommended diagnostic workup in case of a suspected FXIII deficiency. The article also briefly touches on experimental methods used in FXIII research.

Publication History

Received: 15 April 2020

Accepted: 18 May 2020

Publication Date:
31 August 2020 (online)

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