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DOI: 10.1055/a-1171-2003
Whole-body Electromyostimulation plus Caloric Restriction in Metabolic Syndrome
Funding: This research received no external funding.
Abstract
We investigated early effects of Whole-Body Electromyostimulation added to hypocaloric diet on metabolic syndrome features in sedentary middle-aged individuals. We randomly assigned 25 patients to Whole-Body Electromyostimulation plus caloric restriction or caloric restriction alone for 26 weeks. Anthropometrics, blood pressure, fasting glucose and insulin, HOMA-IR, glycated hemoglobin, lipids, uric acid, creatinphosphokynase, C-reactive protein were assessed. Body composition was evaluated with direct-segmental, multi-frequency Bioelectrical Impedance Analysis. Both groups lost approximately 10% of weight, with similar effects on waist circumference and fat mass. Change in free-fat mass was significantly different between groups (caloric restriction −1.5±0.2 vs. Whole-Body Electromyostimulation plus caloric restriction +1.1±0.4 kg, p=0.03). Whole-Body Electromyostimulation plus caloric restriction group experienced greater percent reductions in insulin (−45.5±4.4 vs. −28.2±3.6%, p=0.002), HOMA-IR (–51.3±3.2 vs. –25.1±1.8%, p=0.001), triglycerides (−22.5±2.9 vs. −4.1±1.6%, p=0.004) and triglycerides/HDL (p=0.028). Subjects trained with Whole-Body Electromyostimulation had also significant improvement in systolic pressure (138±4 vs. 126±7 mmHg, p=0.038). No discontinuations for adverse events occurred. In middle-aged sedentary subjects with the metabolic syndrome, Whole-Body Electromyostimulation with caloric restriction for 26 weeks can improve insulin-resistance and lipid profile compared to diet alone. Further studies are needed to ascertain long-term efficacy and feasibility of this approach in individuals with the metabolic syndrome.
Key words
whole-body electromyostimulation - resistance training - metabolic syndrome - cardiovascular risk - insulin-resistance - overweightPublication History
Received: 13 February 2020
Accepted: 21 April 2020
Article published online:
02 June 2020
© 2020. Thieme. All rights reserved.
© Georg Thieme Verlag KG
Stuttgart · New York
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References
- 1 Girman CJ, Rhodes T, Mercuri M. et al. The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol 2004; 93: 136-141
- 2 Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006; 444: 875-880
- 3 Chooi YC, Ding C, Magkos F. The epidemiology of obesity. Metabolism 2019; 92: 6-10
- 4 Cornier MA, Marshall JA, Hill JO. et al. Prevention of overweight/obesity as a strategy to optimize cardiovascular health. Circulation 2011; 124: 840-850
- 5 Eckel RH, Kahn R, Robertson RM. et al. Preventing cardiovascular disease and diabetes: A call to action from the American Diabetes Association and the American Heart Association. Diabetes Care 2006; 29: 1697-1699
- 6 Case CC, Jones PH, Nelson K. et al. Impact of weight loss on the metabolic syndrome. Diabetes Obes Metab 2002; 4: 407-414
- 7 Duncan GE, Perri MG, Theriaque DW. et al. Exercise training, without weight loss, increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults. Diabetes Care 2003; 26: 557-562
- 8 Castellani W, Ianni L, Ricca V. et al. Adherence to structured physical exercise in overweight and obese subjects: A review of psychological models. Eat Weight Disord 2003; 8: 1-11
- 9 Kemmler W, Weissenfels A, Willert S. et al. Efficacy and Safety of Low Frequency Whole-Body Electromyostimulation (WB-EMS) to improve health-related outcomes in non-athletic adults. A systematic review. Front Physiol 2018; 9: 573
- 10 Kemmler W, Kohl M, Freiberger E. et al. Effect of whole-body electromyostimulation and / or protein supplementation on obesity and cardiometabolic risk in older men with sarcopenic obesity: The randomized controlled FranSO trial. BMC Geriatr 2018; 18: 70
- 11 Wittmann K, Sieber C, Von Stengel S. et al. Impact of whole body electromyostimulation on cardiometabolic risk factors in older women with sarcopenic obesity: The randomized controlled FORMOsAsarcopenic obesity study. Clin Interv Aging 2016; 11: 1697-1706
- 12 Amaro-Gahete FJ, De-la-O A, Jurado-Fasoli L. et al. Exercise training as a treatment for cardiometabolic risk in sedentary adults: are physical activity guidelines the best way to improve cardiometabolic health? The FIT-AGEING randomized controlled trial. J Clin Med 2019; 8: 2097
- 13 Amaro-Gahete FJ, De-la-O A, Jurado-Fasoli L. et al. Changes in physical fitness after 12 weeks of structured concurrent exercise training, high intensity interval training, or whole-body electromyostimulation training in sedentary middle-aged adults: A randomized controlled trial. Front Physiol 2019; 10: 451
- 14 Dai X, Zhai L, Chen Q. et al. Two-year-supervised resistance training prevented diabetes incidence in people with prediabetes: A randomised control trial. Diabetes Metab Res Rev 2019; 35: e3143
- 15 Payne WR, Walsh KJ, Harvey JT. et al. Effect of a low-resource-intensive lifestyle modification program incorporating gymnasium-based and home-based resistance training on type 2 diabetes risk in Australian adults. Diabetes Care 2008; 31: 2244-2250
- 16 Mann S, Beedie C, Balducci S. et al. Changes in insulin sensitivity in response to different modalities of exercise: A review of the evidence. Diabetes Metab Res Rev 2014; 30: 257-268
- 17 Grundy SM, Cleeman JI, Daniels SR. et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112: 2735-2752
- 18 Harriss DJ, Macsween A, Atkinson G. Ethical standards in sport and exercise science research: 2020 update. Int J Sports Med 2019; 40: 813-817
- 19 Ling CH, de Craen AJ, Slagboom PE. et al. Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population. Clin Nutr 2011; 30: 610-615
- 20 Armato J, Reaven G, Ruby R. Triglyceride/high-density lipoprotein cholesterol concentration ratio identifies accentuated cardiometabolic risk. Endocr Pract 2015; 21: 495-500
- 21 Matthews DR, Hosker JP, Rudenski AS. et al. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419
- 22 Mifflin MD, Jeor ST, Hill LA. et al. A new predictive equation for resting energy expenditure in healthy individuals. Am J Clin Nutr 1990; 51: 241-247
- 23 Filipovic A, Kleinöder H, Dörmann U. et al. Electromyostimulation–a systematic review of the influence of training regimens and stimulation parameters on effectiveness in electromyostimulation training of selected strength parameters. J Strength Cond Res 2011; 25: 3218-3238
- 24 Kemmler W, Teschler M, Weißenfels A. et al. Effects of whole-body electromyostimulation versus high-intensity resistance exercise on body composition and strength: A randomized controlled study. Evid Based Complement Alternat Med 2016; 9236809
- 25 Amaro-Gahete FJ, De-la-O A, Jurado-Fasoli L. et al. Exercise training increases the S-Klotho plasma levels in sedentary middle-aged adults: A randomised controlled trial. The FIT-AGEING study. J Sports Sci 2019; 37: 2175-2183
- 26 Kemmler W, Weissenfels A, Teschler M. et al. Whole-body electromyostimulation and protein supplementation favorably affect sarcopenic obesity in community-dwelling older men at risk: the randomized controlled FranSO study. Clin Interv Aging 2017; 12: 1503-1513
- 27 von Stengel S, Bebenek M, Engelke K. et al. Whole-body electromyostimulation to fight osteopenia in elderly females: The Randomized Controlled Training and Electrostimulation Trial (TEST-III). J Osteoporos 2015; 643520
- 28 D’Ottavio S, Briotti G, Rosazza C. et al. Effects of two modalities of whole-body electrostimulation programs and resistance circuit training on strength and power. Int J Sports Med 2019; 40: 831-841
- 29 Herrero JA, Izquierdo M, Maffiuletti NA. et al. Electromyostimulation and plyometric training effects on jumping and sprint time. Int J Sports Med 2006; 27: 533-539
- 30 Rubin CT, Capilla E, Luu YK. et al. Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals. Proc Natl Acad Sci USA 2007; 104: 17879-17884
- 31 Teschler M, Wassermann A, Weissenfels A. et al. Short time effect of a single session of intense whole-body electromyostimulation on energy expenditure. A contribution to fat reduction?. Appl Physiol Nutr Metab 2018; 43: 528-530
- 32 Kemmler W, Schliffka R, Mayhew JL. et al. Effects of whole-body electromyostimulation on resting metabolic rate, body composition, and maximum strength in postmenopausal women: The Training and ElectroStimulation Trial. J Strength Cond Res 2010; 24: 1880-1887
- 33 Willert S, Weissenfels A, Kohl M. et al. Effects of whole-body electromyostimulation on the energy-restriction-induced reduction of muscle mass during intended weight loss. Front Physiol 2019; 10: 1012
- 34 Jeppesen J, Hein HO, Suadicani P. et al. Triglyceride concentration and ischemic heart disease: An eight-year follow-up in the Copenhagen Male Study. Circulation 1998; 97: 1029-1036
- 35 Yaspelkis BB. Resistance training improves insulin signaling and action in skeletal muscle. Exerc Sport Sci Rev 2006; 34: 42-46
- 36 Holten MK, Zacho M, Gaster M. et al. Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes 2004; 53: 294-305
- 37 Bird SR, Hawley JA. Update on the effects of physical activity on insulin sensitivity in humans. BMJ Open Sport Exerc Med 2017; 2: e000143
- 38 Lee S, Kuk JL, Davidson LE. et al. Exercise without weight loss is an effective strategy for obesity reduction in obese individuals with and without Type 2 diabetes. J Appl Physiol (1985) 2005; 99: 1220-1225
- 39 MacDonald HV, Johnson BT, Huedo-Medina TB. et al. Dynamic resistance training as stand-alone antihypertensive lifestyle therapy: A meta-analysis. J Am Heart Assoc 2016; 5: e003231
- 40 Cornelissen VA, Fagard RH, Coeckelberghs E. et al. Impact of resistance training on blood pressure and other cardiovascular risk factors: A meta-analysis of randomized, controlled trials. Hypertension 2011; 58: 950-958
- 41 Lemes IR, Ferreira PH, Linares SN. et al. Resistance training reduces systolic blood pressure in metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials. Br J Sports Med 2016; 50: 1438-1442
- 42 Sarafidis PA, Lasaridis AN, Nilsson PM. et al. Validity and reproducibility of HOMA-IR, 1/HOMA-IR, QUICKI and McAuley’s indices in patients with hypertension and type II diabetes. J Hum Hypertens 2007; 21: 709-716