CT-Morphologie von COVID-19: Fallbeispiel und Literaturübersicht

Introduction

In December 2019 a clustering of pneumonia was reported for the first time in Wuhan, Hubei, China [1]. A coronavirus was identified as the pathogen, which has since been given the name Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The disease caused by SARS-CoV-2 is called COVID-19 which has since spread worldwide. In Germany the numbers continue to increase, and the level of COVID-19 lethality in Europe cannot yet be accurately estimated. However, lethality appears to be particularly higher in older patients compared to seasonal influenza [2] [3]. Based on experience in China, computed tomography (CT) is very helpful in COVID-19 in that it can produce an image that is suggestive for diagnosis, and the sensitivity of CT is in some cases higher than that of the current gold standard, real-time polymerase chain reaction (RT-PCR) [4] [5].

The aim of this article is to present a case with COVID-19 pneumonia and to provide an overview of the existing radiological literature on COVID-19.

Publication History

Article published online:
26 March 2020

• References

• 1 Zhu N, Zhang D, Wang W. et al A Novel Coronavirus from Patients with Pneumonia in China, 2019. The New England journal of medicine 2020; 382: 727-733
• 2 Iuliano AD, Roguski KM, Chang HH. et al Estimates of global seasonal influenza-associated respiratory mortality: a modelling study. Lancet (London, England) 2018; 391: 1285-1300
• 3 Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA 2020
• 4 Fang Y, Zhang H, Xie J. et al Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology 2020: 200432
• 5 Ai T, Yang Z, Hou H. et al Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology 2020: 200642
• 6 Bernheim A, Mei X, Huang M. et al Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection. Radiology 2020: 200463
• 7 Pan F, Ye T, Sun P. et al Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia. Radiology 2020: 200370
• 8 Chung M, Bernheim A, Mei X. et al CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV). Radiology 2020: 200230
• 9 Ng MY, Lee EYP, Yang J. et al Imaging Profile of the COVID-19 Infection: Radiologic Findings and Literature Review. Radiology: Cardiothoracic Imaging 2020; 2: e200034
• 10 Song F, Shi N, Shan F. et al Emerging Coronavirus 2019-nCoV Pneumonia. Radiology 2020: 200274
• 11 Shi H, Han X, Jiang N. et al Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. The Lancet Infectious diseases 2020
• 12 Li Y, Xia L. Coronavirus Disease 2019 (COVID-19): Role of Chest CT in Diagnosis and Management. Am J Roentgenol American journal of roentgenology 2020: 1-7
• 13 Li K, Wu J, Wu F. et al The Clinical and Chest CT Features Associated with Severe and Critical COVID-19 Pneumonia. Investigative radiology 2020
• 14 Chen N, Zhou M, Dong X. et al Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet (London, England) 2020; 395: 507-513
• 15 Huang C, Wang Y, Li X. et al Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet (London, England) 2020; 395: 497-506
• 16 Zhao W, Zhong Z, Xie X. et al Relation Between Chest CT Findings and Clinical Conditions of Coronavirus Disease (COVID-19) Pneumonia: A Multicenter Study. Am J Roentgenol American journal of roentgenology 2020: 1-6
• 17 Bai HX, Hsieh B, Xiong Z. et al Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Radiology 2020: 200823
• 18 Xiong Y, Sun D, Liu Y. et al Clinical and High-Resolution CT Features of the COVID-19 Infection: Comparison of the Initial and Follow-up Changes. Investigative radiology 2020
• 19 Xie X, Zhong Z, Zhao W. et al Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCR Testing. Radiology 2020: 200343
• 20 Guan WJ, Ni ZY, Hu Y. et al Clinical Characteristics of Coronavirus Disease 2019 in China. The New England journal of medicine 2020
• 21 Zhang L, Liu Y. Potential interventions for novel coronavirus in China: A systematic review. Journal of medical virology 2020
• 22 Jin YH, Cai L, Cheng ZS. et al A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version). Military Medical Research 2020; 7: 4
• 23 Kanne JP, Little BP, Chung JH. et al Essentials for Radiologists on COVID-19: An Update-Radiology Scientific Expert Panel. Radiology 2020: 200527