Einsatz von Taxanen beim metastasierten HER2-negativen Mammakarzinom – ein Statusreport

Zusammenfassung

Das wichtigste Therapieziel bei der Behandlung von Patientinnen mit metastasiertem Mammakarzinom ist die Erhaltung oder gar Verbesserung der Lebensqualität. Vor diesem Hintergrund sollte die Indikation zur Chemotherapie möglichst zurückhaltend gestellt werden. Falls die Indikation zur palliativen Chemotherapie besteht, ist die Wirkstoffklasse der Taxane als Therapieoption etabliert. Die aktualisierten Leitlinien der Arbeitsgemeinschaft Gynäkologische Onkologie (AGO), Kommission Mamma, der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG) und der Deutschen Krebsgesellschaft e. V. (DKG) geben Empfehlungen, in welcher Therapiesituation welches der zugelassenen Taxane im metastasierten Setting mit höchstmöglicher Evidenz eingesetzt werden kann.

Schlüsselwörter

Mammakarzinom - metastasiert - Chemotherapie - Taxane

• References/Literatur

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