ERCP-related adverse events: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Jean-Marc Dumonceau; Christine Kapral; Lars Aabakken; Ioannis S. Papanikolaou; Andrea Tringali; Geoffroy Vanbiervliet; Torsten Beyna; Mario Dinis-Ribeiro; Istvan Hritz; Alberto Mariani; Gregorios Paspatis; Franco Radaelli; Sundeep Lakhtakia; Andrew M. Veitch; Jeanin E. van Hooft

doi:10.1055/a-1075-4080

Endoscopy, Inhaltsverzeichnis

Endoscopy 2020; 52(02): 127-149
DOI: 10.1055/a-1075-4080

Guideline

ERCP-related adverse events: European Society of Gastrointestinal Endoscopy (ESGE) Guideline

Jean-Marc Dumonceau

¹Gastroenterology Service, Hôpital Civil Marie Curie, Charleroi, Belgium

,

Christine Kapral

²Department of Gastroenterology and Hepatology, Ordensklinikum Barmherzige Schwestern, Linz, Austria

,

Lars Aabakken

³GI Endoscopy Unit, OUS, Rikshospitalet University Hospital, Oslo, Norway

,

Ioannis S. Papanikolaou

⁴Hepatogastroenterology Unit, Second Department of Internal Medicine – Propaedeutic, Research Institute and Diabetes Center, Medical School, National and Kapodistrian University, Attikon University General Hospital, Athens, Greece

,

Andrea Tringali

⁵Digestive Endoscopy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy

⁶Centre for Endoscopic Research, Therapeutics and Training (CERTT), Università Cattolica del Sacro Cuore, Rome, Italy

,

Geoffroy Vanbiervliet

⁷Centre Hospitalier Universitaire de Nice, Pole D.A.R.E, Endoscopie Digestive, Nice, France

,

Torsten Beyna

⁸Department of Internal Medicine and Gastroenterology, Evangelisches Krankenhaus Düsseldorf, Dusseldorf, Germany

,

Mario Dinis-Ribeiro

⁹Gastroenterology Department, Portuguese Oncology Institute of Porto, Portugal

¹⁰Center for Research in Health Technologies and Information Systems (CINTESIS), Faculty of Medicine, Porto, Portugal

,

Istvan Hritz

¹¹Semmelweis University, 1st Department of Surgery, Center for Therapeutic Endoscopy, Budapest, Hungary

,

Alberto Mariani

¹²Division of Pancreato-Biliary Endoscopy and Endosonography, Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute IRCCS, Vita Salute San Raffaele University, Milan, Italy

,

Gregorios Paspatis

¹³Gastroenterology Department, Benizelion General Hospital, Heraklion, Crete, Greece

,

Franco Radaelli

¹⁴Gastroenterology Department, Valduce Hospital, Como, Italy,

,

Sundeep Lakhtakia

¹⁵Asian Institute of Gastroenterology, Hyderabad, India

,

Andrew M. Veitch

¹⁶Department of Gastroenterology, New Cross Hospital, Wolverhampton, UK

,

Jeanin E. van Hooft

¹⁷Department of Gastroenterology and Hepatology, Amsterdam University Medical Centers, University of Amsterdam, The Netherlands

› Institutsangaben

Abstract

Main Recommendations

Prophylaxis

1 ESGE recommends routine rectal administration of 100 mg of diclofenac or indomethacin immediately before endoscopic retrograde cholangiopancreatography (ERCP) in all patients without contraindications to nonsteroidal anti-inflammatory drug administration.

Strong recommendation, moderate quality evidence.

2 ESGE recommends prophylactic pancreatic stenting in selected patients at high risk for post-ERCP pancreatitis (inadvertent guidewire insertion/opacification of the pancreatic duct, double-guidewire cannulation).

Strong recommendation, moderate quality evidence.

3 ESGE suggests against routine endoscopic biliary sphincterotomy before the insertion of a single plastic stent or an uncovered/partially covered self-expandable metal stent for relief of biliary obstruction.

Weak recommendation, moderate quality evidence.

4 ESGE recommends against the routine use of antibiotic prophylaxis before ERCP.

Strong recommendation, moderate quality evidence.

5 ESGE suggests antibiotic prophylaxis before ERCP in the case of anticipated incomplete biliary drainage, for severely immunocompromised patients, and when performing cholangioscopy.

Weak recommendation, moderate quality evidence.

6 ESGE suggests tests of coagulation are not routinely required prior to ERCP for patients who are not on anticoagulants and not jaundiced.

Weak recommendation, low quality evidence.

Treatment

7 ESGE suggests against salvage pancreatic stenting in patients with post-ERCP pancreatitis.

Weak recommendation, low quality evidence.

8 ESGE suggests temporary placement of a biliary fully covered self-expandable metal stent for post-sphincterotomy bleeding refractory to standard hemostatic modalities.

Weak recommendation, low quality evidence.

9 ESGE suggests to evaluate patients with post-ERCP cholangitis by abdominal ultrasonography or computed tomography (CT) scan and, in the absence of improvement with conservative therapy, to consider repeat ERCP. A bile sample should be collected for microbiological examination during repeat ERCP.

Weak recommendation, low quality evidence.

Volltext

Referenzen

References
1 Dumonceau J-M, Riphaus A, Schreiber F. et al. Non-anesthesiologist administration of propofol for gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy, European Society of Gastroenterology and Endoscopy Nurses and Associates Guideline – Updated June 2015. Endoscopy 2015; 47: 1175-1189
2 Dumonceau JM, Garcia-Fernandez FJ, Verdun FR. et al. Radiation protection in digestive endoscopy: European Society of Digestive Endoscopy (ESGE) Guideline. Endoscopy 2012; 44: 408-421
3 Beilenhoff U, Biering H, Blum R. et al. Reprocessing of flexible endoscopes and endoscopic accessories used in gastrointestinal endoscopy: Position Statement of the European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology Nurses and Associates (ESGENA) – Update 2018. Endoscopy 2018; 50: 1205-1234
4 Dumonceau J-M, Tringali A, Papanikolaou I. et al. Endoscopic biliary stenting: indications, choice of stents, and results: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline – Updated October 2017. Endoscopy 2018; 50: 910-930
5 Dumonceau JM, Hassan C, Riphaus A. et al. European Society of Gastrointestinal Endoscopy (ESGE) Guideline Development Policy. Endoscopy 2012; 44: 626-629
6 Cotton PB, Lehman G, Vennes J. et al. Endoscopic sphincterotomy complications and their management: an attempt at consensus. Gastrointest Endosc 1991; 37: 383-393
7 Elmunzer BJ, Scheiman JM, Lehman GA. et al. A randomized trial of rectal indomethacin to prevent post-ERCP pancreatitis. N Engl J Med 2012; 366: 1414-1422
8 Cotton PB, Eisen GM, Aabakken L. et al. A lexicon for endoscopic adverse events: report of an ASGE workshop. Gastrointest Endosc 2010; 71: 446-454
9 Freeman ML, Nelson DB, Sherman S. et al. Complications of endoscopic biliary sphincterotomy. N Engl J Med 1996; 335: 909-918
10 Banks PA, Bollen TL, Dervenis C. et al. Classification of acute pancreatitis – 2012: revision of the Atlanta classification and definitions by international consensus. Gut 2013; 62: 102-111
11 Yokoe M, Hata J, Takada T. et al. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci 2018; 25: 41-54
12 Andriulli A, Loperfido S, Napolitano G. et al. Incidence rates of post-ERCP complications: a systematic survey of prospective studies. Am J Gastroenterol 2007; 102: 1781-1788
13 Kochar B, Akshintala VS, Afghani E. et al. Incidence, severity, and mortality of post-ERCP pancreatitis: a systematic review by using randomized, controlled trials. Gastrointest Endosc 2015; 81: 143-149.e9
14 Li J, Li T, Sun P. et al. Covered versus uncovered self-expandable metal stents for managing malignant distal biliary obstruction: a meta-analysis. PLoS One 2016; 11: e0149066
15 Ferreira LEVVC, Baron TH. Post-sphincterotomy bleeding: who, what, when, and how. Am J Gastroenterol 2007; 102: 2850-2858
16 Cirocchi R, Kelly MD, Griffiths EA. et al. A systematic review of the management and outcome of ERCP related duodenal perforations using a standardized classification system. Surgeon 2017; 15: 379-387
17 Park BK, Seo JH, Jeon HH. et al. A nationwide population-based study of common bile duct stone recurrence after endoscopic stone removal in Korea. J Gastroenterol 2018; 53: 670-678
18 Konstantakis C, Triantos C, Theopistos V. et al. Recurrence of choledocholithiasis following endoscopic bile duct clearance: Long term results and factors associated with recurrent bile duct stones. World J Gastrointest Endosc 2017; 9: 26
19 Berzin TM, Sanaka S, Barnett SR. et al. A prospective assessment of sedation-related adverse events and patient and endoscopist satisfaction in ERCP with anesthesiologist-administered sedation. Gastrointest Endosc 2011; 73: 710-717
20 Behrens A, Kreuzmayr A, Manner H. et al. Acute sedation-associated complications in GI endoscopy (ProSed 2 Study): results from the prospective multicentre electronic registry of sedation-associated complications. Gut 2018;
21 Rahman MR, Perisetti A, Coman R. et al. Duodenoscope-associated infections: update on an emerging problem. Dig Dis Sci 2019; 64: 1409-1418
22 Smeets X, Bouhouch N, Buxbaum J. et al. The revised Atlanta criteria more accurately reflect severity of post-ERCP pancreatitis compared to the consensus criteria. United Eur Gastroenterol J 2019; 7: 557-564
23 Dellinger EP, Forsmark CE, Layer P. et al. Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg 2012; 256: 875-880
24 Bansal SS, Hodson J, Sutcliffe RS. et al. Performance of the revised Atlanta and determinant-based classifications for severity in acute pancreatitis. Br J Surg 2016; 103: 427-433
25 Kiriyama S, Kozaka K, Takada T. et al. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholangitis (with videos). J Hepatobiliary Pancreat Sci 2018; 25: 17-30
26 Stapfer M, Selby RR, Stain SC. et al. Management of duodenal perforation after endoscopic retrograde cholangiopancreatography and sphincterotomy. Ann Surg 2000; 232: 191-198
27 Dumonceau J-M, Andriulli A, Elmunzer BJ. et al. Prophylaxis of post-ERCP pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Updated June 2014. Endoscopy 2014; 46: 799-815
28 Chen J-J, Wang X-M, Liu X-Q. et al. Risk factors for post-ERCP pancreatitis: a systematic review of clinical trials with a large sample size in the past 10 years. Eur J Med Res 2014; 19: 26
29 Ding X, Zhang F, Wang Y. Risk factors for post-ERCP pancreatitis: A systematic review and meta-analysis. Surgeon 2015; 13: 218-229
30 El Nakeeb A, El Hanafy E, Salah T. et al. Post-endoscopic retrograde cholangiopancreatography pancreatitis: Risk factors and predictors of severity. World J Gastrointest Endosc 2016; 8: 709
31 Njei B, Sharma P, McCarty TR. et al. Cannabis use is associated with increased risk of post–endoscopic retrograde cholangiopancreatography pancreatitis: analysis of the US nationwide inpatient sample database, 2004–2014. Pancreas 2018; 47: 1142-1149
32 Tang Z, Yang Y, Yang Z. et al. Early precut sphincterotomy does not increase the risk of adverse events for patients with difficult biliary access: A systematic review of randomized clinical trials with meta-analysis and trial sequential analysis. Medicine (Baltimore) 2018; 97: e12213
33 Sundaralingam P, Masson P, Bourke MJ. Early precut sphincterotomy does not increase risk during endoscopic retrograde cholangiopancreatography in patients with difficult biliary access: a meta-analysis of randomized controlled trials. Clin Gastroenterol Hepatol 2015; 13: 1722-1729
34 Keswani RN, Qumseya BJ, O’Dwyer LC. et al. Association between endoscopist and center endoscopic retrograde cholangiopancreatography volume with procedure success and adverse outcomes: a systematic review and meta-analysis. Clin Gastroenterol Hepatol 2017; 15: 1866-1875
35 Lee H, Cho C-M, Heo J. et al. Impact of hospital volume and the experience of the endoscopist on adverse events related to endoscopic retrograde cholangiopancreatography: a prospective observational study. Gut Liver 2019;
36 Sawas T, Bazerbachi F, Haffar S. et al. End-stage renal disease is associated with increased post endoscopic retrograde cholangiopancreatography adverse events in hospitalized patients. World J Gastroenterol 2018; 24: 4691-4697
37 Kim SB, Kim KH, Kim TN. Safety and efficacy of endoscopic retrograde cholangiopancreatography for choledocholithiasis in long-term dialysis: a propensity score analysis. Dig Dis Sci 2018; 63: 3141-3146
38 Park CH, Jung JH, Nam E. et al. Comparative efficacy of various endoscopic techniques for the treatment of common bile duct stones: a network meta-analysis. Gastrointest Endosc 2018; 87: 43-57.e10
39 Mashiana HS, Dhaliwal AS, Sayles H. et al. Endoscopic retrograde cholangiopancreatography in cirrhosis – a systematic review and meta-analysis focused on adverse events. World J Gastrointest Endosc 2018; 10: 354-366
40 Leal C, Prado V, Colan J. et al. Adverse events and acute chronic liver failure in patients with cirrhosis undergoing endoscopic retrograde cholangiopancreatography: a multicenter matched-cohort study. Am J Gastroenterol 2019; 114: 89-97
41 Nakaji S, Hirata N, Matsui H. et al. Hemodialysis is a strong risk factor for post-endoscopic sphincterotomy bleeding in patients with choledocholithiasis. Endosc Int Open 2018; 6: E568-E574
42 Tsai M-C, Wang C-C, Wang Y-T. et al. Major bleeding risk of endoscopic sphincterotomy versus endoscopic papillary balloon dilatation in hemodialysis patients. Saudi J Gastroenterol 2019; 25: 106-112
43 Hori Y, Naitoh I, Nakazawa T. et al. Feasibility of endoscopic retrograde cholangiopancreatography-related procedures in hemodialysis patients. J Gastroenterol Hepatol 2014; 29: 648-652
44 Cennamo V, Fuccio L, Zagari RM. et al. Can early precut implementation reduce endoscopic retrograde cholangiopancreatography-related complication risk? Meta-analysis of randomized controlled trials. Endoscopy 2010; 42: 381-388
45 Katsinelos P, Lazaraki G, Chatzimavroudis G. et al. Risk factors for therapeutic ERCP-related complications: an analysis of 2,715 cases performed by a single endoscopist. Ann Gastroenterol 2014; 27: 65-72
46 Oh H-C, Hajj IIE, Easler JJ. et al. Post-ERCP bleeding in the era of multiple antiplatelet agents. Gut Liver 2018; 12: 214-218
47 Ikarashi S, Katanuma A, Kin T. et al. Factors associated with delayed hemorrhage after endoscopic sphincterotomy: Japanese large single-center experience. J Gastroenterol 2017; 52: 1258-1265
48 Veitch AM, Vanbiervliet G, Gershlick AH. et al. Endoscopy in patients on antiplatelet or anticoagulant therapy, including direct oral anticoagulants: British Society of Gastroenterology (BSG) and European Society of Gastrointestinal Endoscopy (ESGE) guidelines. Endoscopy 2016; 48: 385-402
49 Lin W-C, Lin H-H, Hung C-Y. et al. Clinical endoscopic management and outcome of post-endoscopic sphincterotomy bleeding. PLoS One 2017; 12: e0177449
50 Bae SS, Lee DW, Han J. et al. Risk factor of bleeding after endoscopic sphincterotomy in average risk patients. Surg Endosc 2019; 33: 3334-3340
51 Manes G, Paspatis G, Aabakken L. et al. Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy 2019; 51: 472-491
52 Liu Y, Su P, Lin Y. et al. Endoscopic sphincterotomy plus balloon dilation versus endoscopic sphincterotomy for choledocholithiasis: A meta-analysis. J Gastroenterol Hepatol 2013; 28: 937-945
53 de Clemente CCJ, Bernardo WM, Franzini TP. et al. Comparison between endoscopic sphincterotomy vs endoscopic sphincterotomy associated with balloon dilation for removal of bile duct stones: A systematic review and meta-analysis based on randomized controlled trials. World J Gastrointest Endosc 2018; 10: 130-144
54 Xu L, Kyaw MH, Tse YK. et al. Endoscopic sphincterotomy with large balloon dilation versus endoscopic sphincterotomy for bile duct stones: a systematic review and meta-analysis. BioMed Res Int 2015; 2015: 1-11
55 Jin PP, Cheng JF, Liu D. et al. Endoscopic papillary large balloon dilation vs endoscopic sphincterotomy for retrieval of common bile duct stones: A meta-analysis. World J Gastroenterol 2014; 20: 5548-5556
56 Hwang JC, Kim JH, Lim SG. et al. Endoscopic large-balloon dilation alone versus endoscopic sphincterotomy plus large-balloon dilation for the treatment of large bile duct stones. BMC Gastroenterol 2013; 13: 15
57 Mirjalili S, Stringer M. The arterial supply of the major duodenal papilla and its relevance to endoscopic sphincterotomy. Endoscopy 2011; 43: 307-311
58 Rey J-F, Beilenhoff U, Neumann CS. et al. European Society of Gastrointestinal Endoscopy (ESGE) guideline: the use of electrosurgical units. Endoscopy 2010; 42: 764-771
59 Verma D, Kapadia A, Adler DG. Pure versus mixed electrosurgical current for endoscopic biliary sphincterotomy: a meta-analysis of adverse outcomes. Gastrointest Endosc 2007; 66: 283-290
60 Li D, Yang M, Chang X. et al. Endocut versus conventional blended electrosurgical current for endoscopic biliary sphincterotomy: a meta-analysis of complications. Dig Dis Sci 2019; 2088-2094
61 Loperfido S, Angelini G, Benedetti G. et al. Major early complications from diagnostic and therapeutic ERCP: a prospective multicenter study. Gastrointest Endosc 1998; 48: 1-10
62 Chen M, Wang L, Wang Y. et al. Risk factor analysis of post-ERCP cholangitis: A single-center experience. Hepatobiliary Pancreat Dis Int HBPD INT 2018; 17: 55-58
63 Lee JG, Lee CE. Infection after ERCP, and antibiotic prophylaxis: a sequential quality-improvement approach over 11 years. Gastrointest Endosc 2008; 67: 476-477
64 Motte S, Deviere J, Dumonceau JM. et al. Risk factors for septicemia following endoscopic biliary stenting. Gastroenterology 1991; 101: 1374-1381
65 Navaneethan U, Jegadeesan R, Nayak S. et al. ERCP-related adverse events in patients with primary sclerosing cholangitis. Gastrointest Endosc 2015; 81: 410-419
66 Sethi A, Chen YK, Austin GL. et al. ERCP with cholangiopancreatoscopy may be associated with higher rates of complications than ERCP alone: a single-center experience. Gastrointest Endosc 2011; 73: 251-256
67 Thosani N, Zubarik RS, Kochar R. et al. Prospective evaluation of bacteremia rates and infectious complications among patients undergoing single-operator choledochoscopy during ERCP. Endoscopy 2016; 48: 424-431
68 Othman MO, Guerrero R, Elhanafi S. et al. A prospective study of the risk of bacteremia in directed cholangioscopic examination of the common bile duct. Gastrointest Endosc 2016; 83: 151-157
69 Jayaraj M, Mohan BP, Dhindsa BS. et al. Periampullary diverticula and ERCP outcomes: a systematic review and meta-analysis. Dig Dis Sci 2019; 64: 1364-1376
70 Enns R, Eloubeidi MA, Mergener K. et al. ERCP-related perforations: risk factors and management. Endoscopy 2002; 34: 293-298
71 Weiser R, Pencovich N, Mlynarsky L. et al. Management of endoscopic retrograde cholangiopancreatography–related perforations: Experience of a tertiary center. Surgery 2017; 161: 920-929
72 Cotton PB, Garrow DA, Gallagher J. et al. Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years. Gastrointest Endosc 2009; 70: 80-88
73 Takano S, Fukasawa M, Shindo H. et al. Risk factors for perforation during endoscopic retrograde cholangiopancreatography in post-reconstruction intestinal tract. World J Clin Cases 2019; 7: 10-18
74 Khan MA, Khan Z, Tombazzi CR. et al. Role of cholecystectomy after endoscopic sphincterotomy in the management of choledocholithiasis in high-risk patients: a systematic review and meta-analysis. J Clin Gastroenterol 2018; 52: 579-589
75 Trap R, Adamsen S, Hart-Hansen O. et al. Severe and fatal complications after diagnostic and therapeutic ERCP: a prospective series of claims to insurance covering public hospitals. Endoscopy 1999; 31: 125-130
76 Cotton PB. Analysis of 59 ERCP lawsuits; mainly about indications. Gastrointest Endosc 2006; 63: 378-382 ; quiz 464
77 Stanciu C, Novis B, Ladas S. et al. Recommendations of the ESGE workshop on Informed consent for Digestive Endoscopy. First European Symposium on Ethics in Gastroenterology and Digestive Endoscopy, Kos, Greece, June 2003. Endoscopy 2003; 35: 772-774
78 Feng Y, Navaneethan U, Zhu X. et al. Prophylactic rectal indomethacin may be ineffective for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis in general patients: A meta-analysis. Dig Endosc 2017; 29: 272-280
79 He X, Zheng W, Ding Y. et al. Rectal indomethacin is protective against pancreatitis after endoscopic retrograde cholangiopancreatography: systematic review and meta-analysis. Gastroenterol Res Pract 2018; 2018: 1-7
80 Yu L-M, Zhao K-J, Lu B. Use of NSAIDS via the rectal route for the prevention of pancreatitis after ERCP in all-risk patients: an updated meta-analysis. Gastroenterol Res Pract 2018; 2018: 1-10
81 Yang C, Zhao Y, Li W. et al. Rectal nonsteroidal anti-inflammatory drugs administration is effective for the prevention of post-ERCP pancreatitis: An updated meta-analysis of randomized controlled trials. Pancreatology 2017; 17: 681-688
82 Inamdar S, Han D, Passi M. et al. Rectal indomethacin is protective against post-ERCP pancreatitis in high-risk patients but not average-risk patients: a systematic review and meta-analysis. Gastrointest Endosc 2017; 85: 67-75
83 Hou Y-C, Hu Q, Huang J. et al. Efficacy and safety of rectal nonsteroidal anti-inflammatory drugs for prophylaxis against post-ERCP pancreatitis: a systematic review and meta-analysis. Sci Rep 2017; 7: 46650
84 Yaghoobi M, Pauls Q, Durkalski V. et al. Incidence and predictors of post-ERCP pancreatitis in patients with suspected sphincter of Oddi dysfunction undergoing biliary or dual sphincterotomy: results from the EPISOD prospective multicenter randomized sham-controlled study. Endoscopy 2015; 47: 884-890
85 Akbar A, Abu Dayyeh BK, Baron TH. et al. Rectal nonsteroidal anti-inflammatory drugs are superior to pancreatic duct stents in preventing pancreatitis after endoscopic retrograde cholangiopancreatography: a network meta-analysis. Clin Gastroenterol Hepatol 2013; 11: 778-783
86 Sethi S, Sethi N, Wadhwa V. et al. A meta-analysis on the role of rectal diclofenac and indomethacin in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis. Pancreas 2014; 43: 190-197
87 Puig I, Calvet X, Baylina M. et al. How and when should NSAIDs be used for preventing post-ERCP pancreatitis? A systematic review and meta-analysis. PLoS One 2014; 9: e92922
88 Levenick JM, Gordon SR, Fadden LL. et al. Rectal indomethacin does not prevent post-ERCP pancreatitis in consecutive patients. Gastroenterology 2016; 150: 911-917 ; quiz e19
89 Lyu Y, Cheng Y, Wang B. et al. What is impact of nonsteroidal anti-inflammatory drugs in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a meta-analysis of randomized controlled trials. BMC Gastroenterol 2018; 18: 106
90 Liu L, Li C, Huang Y. et al. Nonsteroidal anti-inflammatory drugs for endoscopic retrograde cholangiopancreatography postoperative pancreatitis prevention: a systematic review and meta-analysis. J Gastrointest Surg 2019; 23: 1991-2001
91 Yaghoobi M, Alzahrani MA, McNabb-Baltar J. et al. Rectal indomethacin prevents moderate to severe post-ERCP pancreatitis and death and should be used before the procedure: a meta-analysis of aggregate subgroup data. J Can Assoc Gastroenterol 2018; 1: 67-75
92 Ahmad D, Lopez KT, Esmadi MA. et al. The effect of indomethacin in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis. Pancreas 2014; 43: 338-342
93 Serrano J, de Moura D, Bernardo W. et al. Nonsteroidal anti-inflammatory drugs versus placebo for post-endoscopic retrograde cholangiopancreatography pancreatitis: a systematic review and meta-analysis. Endosc Int Open 2019; 07: E477-E486
94 Luo H, Zhao L, Leung J. et al. Routine pre-procedural rectal indometacin versus selective post-procedural rectal indometacin to prevent pancreatitis in patients undergoing endoscopic retrograde cholangiopancreatography: a multicentre, single-blinded, randomised controlled trial. Lancet 2016; 387: 2293-2301
95 Wan J, Ren Y, Zhu Z. et al. How to select patients and timing for rectal indomethacin to prevent post-ERCP pancreatitis: a systematic review and meta-analysis. BMC Gastroenterol 2017; 17: 43
96 Shi N, Deng L, Altaf K. et al. Rectal indomethacin for the prevention of post-ERCP pancreatitis: A meta-analysis of randomized controlled trials. Turk J Gastroenterol 2015; 26: 236-240
97 Ding X, Chen M, Huang S. et al. Nonsteroidal anti-inflammatory drugs for prevention of post-ERCP pancreatitis: a meta-analysis. Gastrointest Endosc 2012; 76: 1152-1159
98 Dai H-F, Wang X-W, Zhao K. Role of nonsteroidal anti-inflammatory drugs in the prevention of post-ERCP pancreatitis: a meta-analysis. Hepatobiliary Pancreat Dis Int 2009; 8: 11-16
99 Elmunzer BJ, Waljee AK, Elta GH. et al. A meta-analysis of rectal NSAIDs in the prevention of post-ERCP pancreatitis. Gut 2008; 57: 1262-1267
100 Sun H-L, Han B, Zhai H-P. et al. Rectal NSAIDs for the prevention of post-ERCP pancreatitis: A meta-analysis of randomized controlled trials. The Surgeon 2014; 12: 141-147
101 Fakoya AOJ, Omenyi P, Anthony P. et al. Stevens–Johnson syndrome and toxic epidermal necrolysis; extensive review of reports of drug-induced etiologies, and possible therapeutic modalities. Open Access Maced J Med Sci 2018; 6: 730-738
102 Gupta L, Martin A, Agarwal N. et al. Guidelines for the management of Stevens–Johnson syndrome/toxic epidermal necrolysis: An Indian perspective. Indian J Dermatol Venereol Leprol 2016; 82: 603
103 Kowalski ML, Agache I, Bavbek S. et al. Diagnosis and management of NSAID‐exacerbated respiratory disease (N‐ERD) – a EAACI position paper. Allergy 2019; 74: 28-39
104 Padberg S, Tissen-Diabaté T, Dathe K. et al. Safety of diclofenac use during early pregnancy: A prospective observational cohort study. Reprod Toxicol 2018; 77: 122-129
105 Pritham UA, McKay L. Safe management of chronic pain in pregnancy in an era of opioid misuse and abuse. J Obstet Gynecol Neonatal Nurs 2014; 43: 554-567
106 Vostinaru O. Adverse effects and drug interactions of the non‐steroidal anti‐inflammatory drugs. In Al-kaf AGA, ed. Nonsteroidal anti-inflammatory drugs. InTech 2017;
107 European Medicines Agency. Ibuprofen- and dexibuprofen-containing medicines. European Medicines Agency. Available from: https://www.ema.europa.eu/en/medicines/human/referrals/ibuprofen-dexibuprofen-containing-medicines Accessed: February 27, 2019
108 Walan A, Bader J-P, Classen M. et al. Effect of omeprazole and ranitidine on ulcer healing and relapse rates in patients with benign gastric ulcer. N Engl J Med 1989; 320: 69-75
109 Patai Á, Solymosi N, Patai AV. Does rectal indomethacin given for prevention of post-ERCP pancreatitis increase bleeding after biliary endoscopic sphincterotomy or cardiovascular mortality? Post hoc analysis using prospective clinical trial data. Medicine (Baltimore) 2014; 93: e159
110 Wu D, Wan J, Xia L. et al. The efficiency of aggressive hydration with lactated Ringer solution for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. J Clin Gastroenterol 2017; 51: e68-e76
111 Zhang Z-F, Duan Z-J, Wang L-X. et al. Aggressive hydration with lactated Ringer solution in prevention of postendoscopic retrograde cholangiopancreatography pancreatitis: a meta-analysis of randomized controlled trials. J Clin Gastroenterol 2017; 51: e17-e26
112 Park C-H, Paik W, Park E. et al. Aggressive intravenous hydration with lactated Ringer’s solution for prevention of post-ERCP pancreatitis: a prospective randomized multicenter clinical trial. Endoscopy 2018; 50: 378-385
113 Ding J, Jin X, Pan Y. et al. Glyceryl trinitrate for prevention of post-ERCP pancreatitis and improve the rate of cannulation: a meta-analysis of prospective, randomized, controlled trials. PLoS ONE 2013; 8: e75645
114 Shao L, Chen Q, Chen M. et al. Nitroglycerin in the prevention of post-ERCP pancreatitis: a meta-analysis. Dig Sci 2010; 55: 1-7
115 Chen B, Fan T, Wang C-H. A meta-analysis for the effect of prophylactic GTN on the incidence of post-ERCP pancreatitis and on the successful rate of cannulation of bile ducts. BMC Gastroenterol 2010; 10: 85
116 Bai Y, Xu C, Yang X. et al. Glyceryl trinitrate for prevention of pancreatitis after endoscopic retrograde cholangiopancreatography: a meta-analysis of randomized, double-blind, placebo-controlled trials. Endoscopy 2009; 41: 690-695
117 Bang UC, Nøjgaard C, Andersen PK. et al. Meta-analysis: Nitroglycerin for prevention of post-ERCP pancreatitis. Aliment Pharmacol Ther 2009; 29: 1078-1085
118 Beauchant M, Ingrand P, Favriel J. et al. Intravenous nitroglycerin for prevention of pancreatitis after therapeutic endoscopic retrograde cholangiography: a randomized, double-blind, placebo-controlled multicenter trial. Endoscopy 2008; 40: 631-636
119 Sotoudehmanesh R, Eloubeidi MA, Asgari AA. et al. A randomized trial of rectal indomethacin and sublingual nitrates to prevent post-ERCP pancreatitis. Am J Gastroenterol 2014; 109: 903-909
120 Tomoda T, Kato H, Ueki T. et al. Combination of diclofenac and sublingual nitrates is superior to diclofenac alone in preventing pancreatitis after endoscopic retrograde cholangiopancreatography. Gastroenterology 2019; 156: 1753-1760.e1
121 Andriulli A, Leandro G, Federici T. et al. Prophylactic administration of somatostatin or gabexate does not prevent pancreatitis after ERCP: an updated meta-analysis. Gastrointest Endosc 2007; 65: 624-632
122 Wang G, Xiao G, Xu L. et al. Effect of somatostatin on prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis and hyperamylasemia: A systematic review and meta-analysis. Pancreatology 2018; 18: 370-378
123 Hu J, Li P-L, Zhang T. et al. Role of somatostatin in preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis: an update meta-analysis. Front Pharmacol 2016; 15: 489
124 Qin X, Lei W, Xing Z. et al. Prophylactic effect of somatostatin in preventing Post-ERCP pancreatitis: an updated meta-analysis. Saudi J Gastroenterol 2015; 21: 372
125 Omata F, Deshpande G, Tokuda Y. et al. Meta-analysis: somatostatin or its long-acting analogue, octreotide, for prophylaxis against post-ERCP pancreatitis. J Gastroenterol 2010; 45: 885-895
126 Rudin D, Kiss A, Wetz RV. et al. Somatostatin and gabexate for post-endoscopic retrograde cholangiopancreatography pancreatitis prevention: meta-analysis of randomized placebo-controlled trials. J Gastroenterol Hepatol 2007; 22: 977-983
127 Bai Y, Ren X, Zhang X-F. et al. Prophylactic somatostatin can reduce incidence of post-ERCP pancreatitis: multicenter randomized controlled trial. Endoscopy 2015; 47: 415-420
128 Bordas JM, Toledo V, Mondelo F. et al. Prevention of pancreatic reactions by bolus somatostatin administration in patients undergoing endoscopic retrograde cholangio-pancreatography and endoscopic sphincterotomy. Horm Res 1988; 29: 106-108
129 Bordas JM, Toledo-Pimentel V, Llach J. et al. Effects of bolus somatostatin in preventing pancreatitis after endoscopic pancreatography: results of a randomized study. Gastrointest Endosc 1998; 47: 230-234
130 Poon RT-P. Intravenous bolus somatostatin after diagnostic cholangiopancreatography reduces the incidence of pancreatitis associated with therapeutic endoscopic retrograde cholangiopancreatography procedures: a randomised controlled trial. Gut 2003; 52: 1768-1773
131 Arvanitidis D, Anagnostopoulos GK, Giannopoulos D. et al. Can somatostatin prevent post-ERCP pancreatitis? Results of a randomized controlled trial. J Gastroenterol Hepatol 2004; 19: 278-282
132 Chan H-H, Lai K-H, Lin C-K. et al. Effect of somatostatin in the prevention of pancreatic complications after endoscopic retrograde cholangiopancreatography. J Chin Med Assoc 2008; 71: 605-609
133 Zhang Y, Chen Q-B, Gao Z-Y. et al. Meta-analysis: octreotide prevents post-ERCP pancreatitis, but only at sufficient doses. Aliment Pharmacol Ther 2009; 29: 1155-1164
134 Yuhara H, Ogawa M, Kawaguchi Y. et al. Pharmacologic prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis: protease inhibitors and NSAIDs in a meta-analysis. J Gastroenterol 2014; 49: 388-399
135 Zhang Z-F, Yang N, Zhao G. et al. Preventive effect of ulinastatin and gabexate mesylate on post-endoscopic retrograde cholangiopancreatography pancreatitis. Chin Med J Eng 2010; 123: 2600-2606
136 Zheng M-H, Bai J-L, Meng M-B. et al. Gabexate mesylate in the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: A systematic review and meta-analysis update. Curr Ther Res 2008; 69: 288-304
137 Zheng M, Chen Y, Yang X. et al. Gabexate in the prophylaxis of post-ERCP pancreatitis: a meta-analysis of randomized controlled trials. BMC Gastroenterol 2007; 7: 6
138 Andriulli A, Leandro G, Niro G. et al. Pharmacologic treatment can prevent pancreatic injury after ERCP: a meta-analysis. Gastrointest Endosc 2000; 51: 1-7
139 Zhu K, Wang J-P, Su J-G. Prophylactic ulinastatin administration for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: A meta-analysis. Exp Ther Med 2017; 14: 3036-3056
140 Yoo K-S, Huh KR, Kim YJ. et al. Nafamostat mesilate for prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis: a prospective, randomized, double-blind, controlled trial. Pancreas 2011; 40: 181-186
141 Choi CW, Kang DH, Kim GH. et al. Nafamostat mesylate in the prevention of post-ERCP pancreatitis and risk factors for post-ERCP pancreatitis. Gastrointest Endosc 2009; 69: e11-8
142 Park KT, Kang DH, Choi CW. et al. Is high-dose nafamostat mesilate effective for the prevention of post-ERCP pancreatitis, especially in high-risk patients?. Pancreas 2011; 40: 1215-1219
143 Ohuchida J, Chijiiwa K, Imamura N. et al. Randomized controlled trial for efficacy of nafamostat mesilate in preventing post–endoscopic retrograde cholangiopancreatography pancreatitis. Pancreas 2014; 44: 415-421
144 Yu G, Li S, Wan R. et al. Nafamostat mesilate for prevention of post-ERCP pancreatitis. A meta-analysis of prospective, randomized, controlled trials. Pancreas 2015; 44: 561-569
145 Kim SJ, Kang DH, Kim HW. et al. A randomized comparative study of 24- and 6-hour infusion of nafamostat mesilate for the prevention of post–endoscopic retrograde cholangiopancreatography pancreatitis: a prospective randomized comparison trial. Pancreas 2016; 45: 1179-1183
146 Xu LH, Qian JB, Gu LG. et al. Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis by epinephrine sprayed on the papilla: Prevention of PEP by epinephrine spray. J Gastroenterol Hepatol 2011; 26: 1139-1144
147 Matsushita M, Takakuwa H, Shimeno N. et al. Epinephrine sprayed on the papilla for prevention of post-ERCP pancreatitis. J Gastroenterol 2009; 44: 71-75
148 Akshintala VS, Hutfless SM, Colantuoni E. et al. Systematic review with network meta-analysis: pharmacological prophylaxis against post-ERCP pancreatitis. Aliment Pharmacol Ther 2013; 38: 1325-1337
149 Vadalà di Prampero SF, Faleschini G, Panic N. et al. Endoscopic and pharmacological treatment for prophylaxis against postendoscopic retrograde cholangiopancreatography pancreatitis: a meta-analysis and systematic review. Eur J Gastroenterol Hepatol 2016; 28: 1415-1424
150 da Cruz Portela J, Marques Bernardo W, de Moura D. et al. Pancreatic stent placement for prevention of post-ERCP pancreatitis in high-risk patients: a systematic review and meta-analysis. JOP 2019; 20: 16-23
151 Fan J-H. Updated meta-analysis of pancreatic stent placement in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis. World J Gastroenterol 2015; 21: 7577-7583
152 Mazaki T, Mado K, Masuda H. et al. Prophylactic pancreatic stent placement and post-ERCP pancreatitis: an updated meta-analysis. J Gastroenterol 2014; 49: 343-355
153 Shi Q-Q, Ning X-Y, Zhan L-L. et al. Placement of prophylactic pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients: a meta-analysis. World J Gastroenterol 2014; 20: 7040-7048
154 Choudhary A, Bechtold ML, Arif M. et al. Pancreatic stents for prophylaxis against post-ERCP pancreatitis: a meta-analysis and systematic review. Gastrointest Endosc 2011; 73: 275-282
155 Sugimoto M, Takagi T, Suzuki R. et al. Pancreatic stents to prevent post-endoscopic retrograde cholangiopancreatography pancreatitis: A meta-analysis. World J Meta-Anal 2019; 7: 249-258
156 Phillip V, Pukitis A, Epstein A. et al. Pancreatic stenting to prevent post-ERCP pancreatitis: a randomized multicenter trial. Endosc Int Open 2019; 07: E860-E868
157 Ito K, Fujita N, Kanno A. et al. Risk factors for post-ERCP pancreatitis in high risk patients who have undergone prophylactic pancreatic duct stenting: a multicenter retrospective study. Intern Med 2011; 50: 2927-2932
158 Das A, Singh P, Sivak MV. et al. Pancreatic-stent placement for prevention of post-ERCP pancreatitis: a cost-effectiveness analysis. Gastrointest Endosc 2007; 65: 960-968
159 Moffatt DC, Coté GA, Fogel EL. et al. Acute pancreatitis after removal of retained prophylactic pancreatic stents. Gastrointest Endosc 2011; 73: 980-986
160 Afghani E, Akshintala VS, Khashab MA. et al. 5-Fr vs. 3-Fr pancreatic stents for the prevention of post-ERCP pancreatitis in high-risk patients: a systematic review and network meta-analysis. Endoscopy 2014; 46: 573-580
161 Chahal P, Tarnasky P, Petersen B. et al. Short 5Fr vs long 3Fr pancreatic stents in patients at high risk for post- endoscopic cholangiopancreatography pancreatitis. Clin Gastroenterol Hepatol 2009; 7: 834-839
162 Zolotarevsky E, Fehmi S, Anderson M. et al. Prophylactic 5-Fr pancreatic duct stents are superior to 3-Fr stents: a randomized controlled trial. Endoscopy 2011; 43: 325-330
163 He Q, Wang L, Peng C. et al. Modified prophylactic 5-fr pancreatic duct stent enhances the rate of spontaneous dislodgement: A multicenter randomized controlled trial. United Eur Gastroenterol J 2018; 6: 1519-1526
164 Matsumoto K, Katanuma A, Maguchi H. Endoscopic removal technique of migrated pancreatic plastic stents. J Hepato-Biliary-Pancreat Sci 2014; 21: E34-E40
165 Fujisawa T, Kagawa K, Ochiai K. et al. Prophylactic efficacy of 3- or 5-cm pancreatic stents for preventing post-ERCP pancreatitis: A prospective, randomized trial. J Clin Gastroenterol 2016; 50: e30-e34
166 Sugimoto M, Takagi T, Suzuki R. et al. Pancreatic stents for the prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis should be inserted up to the pancreatic body or tail. World J Gastroenterol 2018; 24: 2392-2399
167 Conigliaro R, Manta R, Bertani H. et al. Pancreatic duct stenting for the duration of ERCP only does not prevent pancreatitis after accidental pancreatic duct cannulation: a prospective randomized trial. Surg Endosc 2013; 27: 569-574
168 Dultz G, Gerber L, Zeuzem S. et al. Prolonged retention of prophylactic pancreatic stents is not associated with increased complications. Pancreatology 2019; 19: 39-43
169 Elmunzer BJ, Higgins PDR, Saini SD. et al. Does rectal indomethacin eliminate the need for prophylactic pancreatic stent placement in patients undergoing high-risk ERCP? Post hoc efficacy and cost-benefit analyses using prospective clinical trial data. Am J Gastroenterol 2013; 108: 410-415
170 Abdelfatah MM, Gochanour E, Koutlas NJ. et al. Post–endoscopic retrograde cholangiopancreatography pancreatitis: single versus dual prophylactic modalities. Pancreas 2019; 48: e24
171 Sotoudehmanesh R, Ali-Asgari A, Khatibian M. et al. Pharmacological prophylaxis versus pancreatic duct stenting plus pharmacological prophylaxis for prevention of post-ERCP pancreatitis in high risk patients: a randomized trial. Endoscopy 2019; 51: 915-921
172 Hosseini M, Shalchiantabrizi P, Yektaroudy K. et al. Prophylactic effect of rectal indomethacin administration, with and without intravenous hydration, on development of endoscopic retrograde cholangiopancreatography pancreatitis episodes: a randomized clinical trial. Arch Iran Med 2016; 19: 538-543
173 Mok SRS, Ho HC, Shah P. et al. Lactated Ringer’s solution in combination with rectal indomethacin for prevention of post-ERCP pancreatitis and readmission: a prospective randomized, double-blinded, placebo-controlled trial. Gastrointest Endosc 2017; 85: 1005-1013
174 Kamal A, Akshintala VS, Talukdar R. et al. A randomized trial of topical epinephrine and rectal indomethacin for preventing post-endoscopic retrograde cholangiopancreatography pancreatitis in high-risk patients. Am J Gastroenterol 2019; 114: 339-347
175 Luo H, Wang X, Zhang R. et al. Rectal indomethacin and spraying of duodenal papilla with epinephrine increases risk of pancreatitis following endoscopic retrograde cholangiopancreatography. Clin Gastroenterol Hepatol 2019; 17: 1597-1606
176 Testoni PA, Mariani A, Aabakken L. et al. Papillary cannulation and sphincterotomy techniques at ERCP: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline. Endoscopy 2016; 48: 657-683
177 Bassan MS, Sundaralingam P, Fanning SB. et al. The impact of wire caliber on ERCP outcomes: a multicenter randomized controlled trial of 0.025-inch and 0.035-inch guidewires. Gastrointest Endosc 2018; 87: 1454-1460
178 Park J, Jeong S, Lee DH. Effectiveness of a novel highly flexible‐tip guidewire on selective biliary cannulation compared to conventional guidewire: Randomized controlled study. Dig Endosc 2018; 30: 245-251
179 Kurita A, Kudo Y, Yoshimura K. et al. Comparison between a rotatable sphincterotome and a conventional sphincterotome for selective bile duct cannulation. Endoscopy 2019; 51: 852-857
180 Bassi M, Luigiano C, Ghersi S. et al. A multicenter randomized trial comparing the use of touch versus no-touch guidewire technique for deep biliary cannulation: the TNT study. Gastrointest Endosc 2018; 87: 196-201
181 Chen J, Wan JH, Wu DY. et al. Assessing quality of precut sphincterotomy in patients with difficult biliary access: an updated meta-analysis of randomized controlled trials. J Clin Gastroenterol 2018; 52: 573-578
182 Dumonceau JM, Devière J, Cremer M. A new method of achieving deep cannulation of the common bile duct during endoscopic retrograde cholangiopancreatography. Endoscopy 1998; 30: S80
183 Tse F, Yuan Y, Moayyedi P. et al. Double-guidewire technique in difficult biliary cannulation for the prevention of post-ERCP pancreatitis: a systematic review and meta-analysis. Endoscopy 2017; 49: 15-26
184 Ito K, Fujita N, Noda Y. et al. Can pancreatic duct stenting prevent post-ERCP pancreatitis in patients who undergo pancreatic duct guidewire placement for achieving selective biliary cannulation? A prospective randomized controlled trial.. J Gastroenterol 2010; 45: 1183-1191
185 Eminler AT, Parlak E, Koksal AS. et al. Wire-guided cannulation over a pancreatic stent method increases the need for needle-knife precutting in patients with difficult biliary cannulations. Gastrointest Endosc 2019; 89: 301-308
186 Pécsi D, Farkas N, Hegyi P. et al. Transpancreatic sphincterotomy is effective and safe in expert hands on the short term. Dig Dis Sci 2019; 64: 2429-2444
187 Mangiavillano B, Montale A, Frazzoni L. et al. Endoscopic biliary self-expandable metallic stent in malignant biliary obstruction with or without sphincterotomy: systematic review and meta-analysis. Endosc Int Open 2019; 07: E26-E35
188 Sawas T, Arwani N, Al HalabiS. Sphincterotomy with endoscopic biliary drainage for severe acute cholangitis: a meta-analysis. Endosc Int Open 2017; 5: E103-E109
189 Martins FP, Kahaleh M, Ferrari AP. Management of liver transplantation biliary stricture: Results from a tertiary hospital. World J Gastrointest Endosc 2015; 7: 747-757
190 Sezgin O, Altintas E, Ates F. et al. Air cholangiogram is not sufficent to detect common bile duct stones during ERCP. Turk J Gastroenterol 2014; 25: 319-320
191 Navaneethan U, Lourdusamy D, Gutierrez N. et al. New approach to decrease post-ERCP adverse events in patients with primary sclerosing cholangitis. Endosc Int Open 2017; 05: E710-E717
192 Ricci C, Pagano N, Taffurelli G. et al. Comparison of efficacy and safety of 4 combinations of laparoscopic and intraoperative techniques for management of gallstone disease with biliary duct calculi: a systematic review and network meta-analysis. JAMA Surg 2018; 153: e181167
193 Harris A, Chan AC, Torres-Viera C. et al. Meta-analysis of antibiotic prophylaxis in endoscopic retrograde cholangiopancreatography (ERCP). Endoscopy 1999; 31: 718-724
194 Bai Y, Gao F, Gao J. et al. Prophylactic antibiotics cannot prevent endoscopic retrograde cholangiopancreatography-induced cholangitis: a meta-analysis. Pancreas 2009; 38: 126-130
195 Brand M, Bizos D, O’Farrell PJ. Antibiotic prophylaxis for patients undergoing elective endoscopic retrograde cholangiopancreatography. Cochrane Database Syst Rev 2010; CD007345
196 Olsson G, Arnelo U, Lundell L. et al. The role of antibiotic prophylaxis in routine endoscopic retrograde cholangiopancreatography investigations as assessed prospectively in a nationwide study cohort. Scand J Gastroenterol 2015; 50: 924-931
197 Wobser H, Gunesch A, Klebl F. Prophylaxis of post-ERC infectious complications in patients with biliary obstruction by adding antimicrobial agents into ERC contrast media – a single center retrospective study. BMC Gastroenterol 2017; 17: 10
198 Norouzi A, Khatibian M, Afroogh R. et al. The effect of adding gentamicin to contrast media for prevention of cholangitis after biliary stenting for non-calculous biliary obstruction, a randomized controlled trial. Indian J Gastroenterol 2013; 32: 18-21
199 Du M, Suo J, Liu B. et al. Post-ERCP infection and its epidemiological and clinical characteristics in a large Chinese tertiary hospital: a 4-year surveillance study. Antimicrob Resist Infect Control 2017; 6: 131
200 Masadeh M, Chandra S, Livorsi D. et al. Evaluation of biliary bacterial resistance in patients with frequent biliary instrumentation, one size does not fit all. Dig Dis Sci 2018; 63: 3474-3479
201 Minami T, Sasaki T, Serikawa M. et al. Antibiotic prophylaxis for endoscopic retrograde chlangiopancreatography increases the detection rate of drug-resistant bacteria in bile. J Hepatobiliary Pancreat Sci 2014; 21: 712-718
202 Segal JB, Dzik WH. Transfusion Medicine/Hemostasis Clinical Trials Network. Paucity of studies to support that abnormal coagulation test results predict bleeding in the setting of invasive procedures: an evidence-based review. Transfusion (Paris) 2005; 45: 1413-1425
203 Oren A, Breumelhof R, Timmer R. et al. Abnormal clotting parameters before therapeutic ERCP: do they predict major bleeding?. Eur J Gastroenterol Hepatol 1999; 11: 1093-1097
204 Tripodi A, Caldwell SH, Hoffman M. et al. Review article: the prothrombin time test as a measure of bleeding risk and prognosis in liver disease. Aliment Pharmacol Ther 2007; 26: 141-148
205 Deitcher SR. Interpretation of the international normalised ratio in patients with liver disease. Lancet Lond Engl 2002; 359: 47-48
206 Kovacs MJ, Wong A, MacKinnon K. et al. Assessment of the validity of the INR system for patients with liver impairment. Thromb Haemost 1994; 71: 727-730
207 Adike A, Al-Qaisi M, Baffy NJ. et al. International normalized ratio does not predict gastrointestinal bleeding after endoscopic retrograde cholangiopancreatography in patients with cirrhosis. Gastroenterol Res 2017; 10: 177-181
208 Egan RJ, Nicholls J, Walker S. et al. Routine coagulation screening is an unnecessary step prior to ERCP in patients without biochemical evidence of jaundice: a cross-centre study. Int J Surg Lond Engl 2014; 12: 1216-1220
209 Nakaji S, Hirata N, Matsui H. et al. Hemodialysis is a strong risk factor for post-endoscopic sphincterotomy bleeding in patients with choledocholithiasis. Endosc Int Open 2018; 06: E568-E574
210 Bae SS, Lee DW, Han J. et al. Risk factor of bleeding after endoscopic sphincterotomy in average risk patients. Surg Endosc 2019; 33: 3334-3340
211 Wang P, Li Z-S, Liu F. et al. Risk factors for ERCP-related complications: a prospective multicenter study. Am J Gastroenterol 2009; 104: 31-40
212 Williams EJ, Taylor S, Fairclough P. et al. Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy 2007; 39: 793-801
213 Masci E, Toti G, Mariani A. et al. Complications of diagnostic and therapeutic ERCP: a prospective multicenter study. Am J Gastroenterol 2001; 96: 417-423
214 Leung WK, But DY, Wong S-Y. et al. Prevention of post-sphincterotomy bleeding by proton pump inhibitor: A randomized controlled trial. J Dig Dis 2018; 19: 369-376
215 Gottlieb K, Sherman S, Pezzi J. et al. Early recognition of post-ERCP pancreatitis by clinical assessment and serum pancreatic enzymes. Am J Gastroenterol 1996; 91: 1553-1557
216 Testoni PA, Bagnolo F, Caporuscio S. et al. Serum amylase measured four hours after endoscopic sphincterotomy is a reliable predictor of postprocedure pancreatitis. Am J Gastroenterol 1999; 94: 1235-1241
217 Thomas PR, Sengupta S. Prediction of pancreatitis following endoscopic retrograde cholangiopancreatography by the 4-h post procedure amylase level. J Gastroenterol Hepatol 2001; 16: 923-926
218 Kapetanos D, Kokozidis G, Kinigopoulou P. et al. The value of serum amylase and elastase measurements in the prediction of post-ERCP acute pancreatitis. Hepatogastroenterology 2007; 54: 556-560
219 Ito K, Fujita N, Noda Y. et al. Relationship between post-ERCP pancreatitis and the change of serum amylase level after the procedure. World J Gastroenterol 2007; 13: 3855-3860
220 Artifon ELA, Chu A, Freeman M. et al. A comparison of the consensus and clinical definitions of pancreatitis with a proposal to redefine post-endoscopic retrograde cholangiopancreatography pancreatitis. Pancreas 2010; 39: 530-535
221 Sutton VR, Hong MKY, Thomas PR. Using the 4-hour post-ERCP amylase level to predict post-ERCP pancreatitis. JOP 2011; 12: 372-376
222 Lee YK, Yang MJ, Kim SS. et al. Prediction of post-endoscopic retrograde cholangiopancreatography pancreatitis using 4-hour post-endoscopic retrograde cholangiopancreatography serum amylase and lipase levels. J Korean Med Sci 2017; 32: 1814-1819
223 Minakari M, Sebghatollahi V, Sattari M. et al. Serum amylase and lipase levels for prediction of postendoscopic retrograde cholangiopancreatography pancreatitis. J Res Med Sci 2018; 23: 54
224 Papachristos A, Howard T, Thomson BN. et al. Predicting post-endoscopic retrograde cholangiopancreatography pancreatitis using the 4-h serum lipase level: Predicting post-ERCP pancreatitis. ANZ J Surg 2018; 88: 82-86
225 Zhang Y, Ye X, Wan X. et al. Serum lipase as a biomarker for early prediction and diagnosis of post-endoscopic retrograde cholangiopancreatography pancreatitis. Ir J Med Sci 2019;
226 Choi YH, Jang DK, Lee SH. et al. Utility of serum phosphate as a marker for predicting the severity of post-endoscopic retrograde cholangiopancreatography pancreatitis. United Eur Gastroenterol J 2018; 6: 895-901
227 Madácsy L, Kurucsai G, Joó I. et al. Rescue ERCP and insertion of a small-caliber pancreatic stent to prevent the evolution of severe post-ERCP pancreatitis: a case-controlled series. Surg Endosc 2009; 23: 1887-1893
228 Kerdsirichairat T, Attam R, Arain M. et al. Urgent ERCP with pancreatic stent placement or replacement for salvage of post-ERCP pancreatitis. Endoscopy 2014; 46: 1085-1094
229 Karjula H, Nordblad Schmidt P. et al. Prophylactic pancreatic duct stenting in severe acute necrotizing pancreatitis: a prospective randomized study. Endoscopy 2019; 51: 1027-1034
230 Lanas A, Dumonceau J-M, Hunt RH. et al. Non-variceal upper gastrointestinal bleeding. Nat Rev Dis Primers 2018; 4: 18020
231 Wilcox CM, Canakis J, Mönkemüller KE. et al. Patterns of bleeding after endoscopic sphincterotomy, the subsequent risk of bleeding, and the role of epinephrine injection. Am J Gastroenterol 2004; 99: 244-248
232 Katsinelos P, Kountouras J, Chatzimavroudis G. et al. A novel technique of injection treatment for endoscopic sphincterotomy-induced hemorrhage. Endoscopy 2007; 39: 631-636
233 Parlak E, Dişibeyaz S, Köksal AŞ. et al. Factors affecting the success of endoscopic treatment of sphincterotomy bleeding. Clin Res Hepatol Gastroenterol 2013; 37: 391-399
234 Tsou Y-K, Lin C-H, Liu N-J. et al. Treating delayed endoscopic sphincterotomy-induced bleeding: epinephrine injection with or without thermotherapy. World J Gastroenterol 2009; 15: 4823-4828
235 Chon HK, Kim TH. Endoclip therapy of post-sphincterotomy bleeding using a transparent cap-fitted forward-viewing gastroscope. Surg Endosc 2017; 31: 2783-2788
236 Liu F, Wang G-Y, Li Z-S. Cap-assisted hemoclip application with forward-viewing endoscope for hemorrhage induced by endoscopic sphincterotomy: a prospective case series study. BMC Gastroenterol 2015; 15: 135
237 Aranez JL, Miller J, Hughes M. et al. A novel, duodenoscope-friendly endoscopic clip for treating massive upper-GI bleeding secondary to a Dieulafoy lesion. VideoGIE 2018; 3: 205-206
238 Katsinelos P, Kountouras J, Chatzimavroudis G. et al. Endoscopic hemostasis using monopolar coagulation for postendoscopic sphincterotomy bleeding refractory to injection treatment. Surg Laparosc Endosc Percutan Tech 2010; 20: 84-88
239 Maleux G, Bielen J, Laenen A. et al. Embolization of post-biliary sphincterotomy bleeding refractory to medical and endoscopic therapy: technical results, clinical efficacy and predictors of outcome. Eur Radiol 2014; 24: 2779-2786
240 Cochrane J, Schlepp G. Comparing endoscopic intervention against fully covered self-expanding metal stent placement for post-endoscopic sphincterotomy bleed (CEASE Study). Endosc Int Open 2016; 04: E1261-E1264
241 Appleby VJ, Hutchinson JM, Beckett CJ. et al. Use of the haemostatic agent TC-325 in the treatment of bleeding secondary to endoscopic retrograde cholangiopancreatography sphincterotomy. QJM 2015; 108: 79-80
242 Mutignani M, Seerden T, Tringali A. et al. Endoscopic hemostasis with fibrin glue for refractory postsphincterotomy and postpapillectomy bleeding. Gastrointest Endosc 2010; 71: 856-860
243 Lee M-H, Tsou Y-K, Lin C-H. et al. Predictors of re-bleeding after endoscopic hemostasis for delayed post-endoscopic sphincterotomy bleeding. World J Gastroenterol 2016; 22: 3196
244 Kim HJ, Kim MH, Kim DI. et al. Endoscopic hemostasis in sphincterotomy-induced hemorrhage: its efficacy and safety. Endoscopy 1999; 31: 431-436
245 Paspatis GA, Dumonceau J-M, Barthet M. et al. Diagnosis and management of iatrogenic endoscopic perforations: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy 2014; 46: 693-711
246 Titare PU, Sonawane BD, Tembhekar NG. et al. A study of diagnostic accuracy and utility of ultrasound in the assessment of biliary stent. J Evol Med Dent Sci 2015; 4: 13624-13630
247 Manoharan D, Srivastava DN, Gupta AK. et al. Complications of endoscopic retrograde cholangiopancreatography: an imaging review. Abdom Radiol 2019; 44: 2205-2216
248 Tonolini M, Pagani A, Bianco R. Cross-sectional imaging of common and unusual complications after endoscopic retrograde cholangiopancreatography. Insights Imaging 2015; 6: 323-338
249 Thomas S, Patel RP, Oto A. Resolution of pneumobilia as a predictor of biliary stent occlusion. Clin Imaging 2015; 39: 650-653
250 Chandra S, Klair JS, Soota K. et al. Endoscopic retrograde cholangio-pancreatography-obtained bile culture can guide antibiotic therapy in acute cholangitis. Dig Dis 2019; 37: 155-160
251 Negm AA, Schott A, Vonberg R-P. et al. Routine bile collection for microbiological analysis during cholangiography and its impact on the management of cholangitis. Gastrointest Endosc 2010; 72: 284-291

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