Die tiefe Hirnstimulation ist eine etablierte und evidenzbasierte
Therapieoption für die Behandlung des fortgeschrittenen Morbus
Parkinson. Es handelt sich um eine symptomatische Behandlung mit dem
primären Ziel, die Lebensqualität des Patienten zu
verbessern. Der operative Eingriff gilt als relativ komplikationsarm.
Abstract
Deep brain stimulation is an established and evidence-based therapeutic
option for the treatment of advanced Parkinsonʼs disease. Main indication
and inclusion criteria are the presence of idiopathic Parkinsonism with
motor fluctuations and/or dyskinesias and/or with medication
refractory tremor, a significant improvement of akinesia/rigidity in
response to dopaminergic medication, the absence of relevant cognitive
deficits and other significant comorbidities. DBS neurosurgery has a low
risk of complications. The clinical programming should follow an established
monopolar review algorithm. Regular follow-up visits are required for
stimulation monitoring.
Schlüsselwörter
Morbus Parkinson - Tiefe Hirnstimulation - Nucleus subthalamicus
Key words
Parkinsonʼs disease - Deep brain stimulation - Subthalamic nucleus