Nuklearmedizin 2019; 58(05): 403-404
DOI: 10.1055/a-0972-0698
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Diagnosis of Huntington’s disease via sequential 18F-DOPA and 18F-FDG PET/MRI

Erstdiagnose eines Morbus Huntington mittels 18F-DOPA und 18F-FDG PET/MRI
Enrico Michler
Sebastian Hoberück
Filippo Martino
Ivan Platzek
Jörg Kotzerke
Further Information

Publication History

Publication Date:
25 July 2019 (online)


Cases of rare movement disorders like Huntington’s disease (HD) are not easy to diagnose, especially when occurring sporadically, without documented family history. In HD patients, MRI scans commonly feature atrophy of the striatum and reduced volume of white matter. But if morphological findings remain unspecific, functional PET imaging could provide valuable information to further clarify diagnosis. We present a case report of a 56-year-old woman suffering from mild hypokinetic-rigid syndrome and depression, suspicious of Parkinson’s disease, who was referred to 18F-DOPA and 18F-FDG PET/MRI scans at our department.