Open Access
CC BY-NC-ND 4.0 · Endosc Int Open 2019; 07(07): E922-E930
DOI: 10.1055/a-0915-9594
Review
Owner and Copyright © Georg Thieme Verlag KG 2019

Endoscopic ultrasonography in pancreatic diseases: advances in tissue acquisition

Ioannis V. Mitselos
1   Department of Gastroenterology, School of Health Sciences, University Hospital of Ioannina, Faculty of Medicine, University of Ioannina, Ioannina, Greece
,
Ioannis Karoumpalis
2   Department of Gastroenterology, General National Hospital of Athens “G. Gennimatas”, Athens, Greece
,
Vasileios I. Theopistos
1   Department of Gastroenterology, School of Health Sciences, University Hospital of Ioannina, Faculty of Medicine, University of Ioannina, Ioannina, Greece
,
Dimitrios Tzilves
3   Department of Gastroenterology, General Hospital of Thessaloniki “Theageneion”,Thessaloniki, Greece
,
Dimitrios K. Christodoulou
1   Department of Gastroenterology, School of Health Sciences, University Hospital of Ioannina, Faculty of Medicine, University of Ioannina, Ioannina, Greece
› Author Affiliations
Further Information

Publication History

submitted 19 January 2019

accepted after revision 09 April 2019

Publication Date:
11 July 2019 (online)

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Abstract

Background and study aims Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) improved the diagnostic performance and upgraded the role of endoscopic ultrasonography (EUS) into an interventional modality, able to guide patient management and treatment.This review aimed to highlight the advances, emerging practices, procedural techniques and technological innovations in EUS tissue acquisition in pancreatic diseases.

Methods A thorough review of the literature was performed using PubMed to identify articles that describe techniques, advances, and practices in EUS tissue acquisition in gastrointestinal diseases.

Conclusion Since the first EUS-FNA procedure, EUS guided-tissue acquisition has been evolving continuously. Development of needles with innovative tip design enabled procurement of larger samples with preserved histological architecture. Moreover, sampling techniques and complementary methods, such as contrast harmonic imaging and EUS-elastography, have been introduced in an effort to improve diagnostic performance and sample adequacy.