Planta Med 2019; 85(07): 528-534
DOI: 10.1055/a-0873-1494
Biological and Pharmacological Activity
Reviews
Georg Thieme Verlag KG Stuttgart · New York

Plant Allergen-Induced Contact Dermatitis

Philipp R. Esser
1   Allergy Research Group, Department of Dermatology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Germany
,
Sabine Mueller
2   Clinical Allergology, Department of Dermatology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Germany
,
Stefan F. Martin
1   Allergy Research Group, Department of Dermatology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Germany
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Publikationsverlauf

received 23. November 2018
revised 07. März 2019

accepted 08. März 2019

Publikationsdatum:
15. März 2019 (online)

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Abstract

Although manifold beneficial effects of plant compounds for the treatment of skin disorders are known, cutaneous exposure to plants can also result in various types of incompatibility reactions such as contact dermatitis. In this mini-review, we briefly describe the different clinical forms of contact dermatitis (photoinduced, irritative, and allergic form) and highlight recent publications in the field of contact dermatitis. Major topics are recent recommendations regarding testing for plant contact dermatitis, advances in understanding the immunological mechanisms of plant contact dermatitis, and case reports for plant contact dermatitis. Unfortunately, most people still associate the terms “healthy and safe to use” with plant compounds due to their natural origin, leading to an increased utilization, be it for home-made remedies or as cosmetics. Therefore, it is on the one hand important to raise awareness in a broad audience that plants may cause contact dermatitis and on the other hand to indicate to clinicians that plants should be included in a patch test if a history of plant exposure exists.