CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2019; 79(03): 281-285
DOI: 10.1055/a-0746-8985
GebFra Science
Review/Übersicht
Georg Thieme Verlag KG Stuttgart · New York

Female Adnexal Tumour of Probable Wolffian Origin (FATWO): Review of the Literature

Article in several languages: English | deutsch
Theresa Barbara Hübner
1   Department of Obstetrics and Gynaecology, Würzburg University Medical Centre, Würzburg, Germany
,
Michael Schwab
1   Department of Obstetrics and Gynaecology, Würzburg University Medical Centre, Würzburg, Germany
,
Elena Hartmann
2   Department of Pathology, Universitiy of Würzburg and Comprehensive Cancer Center (CCC) Mainfranken, Würzburg, Germany
,
Doris Mayr
3   Institute of Pathology, Ludwig-Maximilians-University Munich, Munich, Germany
,
Annette Thurner
4   Department of Diagnostic Radiology, Würzburg University Medical Centre, Würzburg, Germany
,
Thorsten Bley
4   Department of Diagnostic Radiology, Würzburg University Medical Centre, Würzburg, Germany
,
Achim Wöckel
1   Department of Obstetrics and Gynaecology, Würzburg University Medical Centre, Würzburg, Germany
,
Daniel Herr
1   Department of Obstetrics and Gynaecology, Würzburg University Medical Centre, Würzburg, Germany
› Author Affiliations
Further Information

Publication History

received 21 July 2018
revised 11 September 2018

accepted 18 September 2018

Publication Date:
12 March 2019 (online)

Abstract

FATWO (female adnexal tumour of probable Wolffian origin) denotes a rare tumour of the female adnexa which has been described in nearly 80 cases worldwide and which presumably originates in the remains of the Wolffian ducts. In 10 to 20 percent of patients, a metastasis or recurrence was seen subsequently and for this reason, a malignant potential is attributed to the FATWO. Because of the small number of cases, there is no clear therapeutic recommendation. The method of choice currently is surgical treatment with hysterectomy and adnexectomy. The benefit of radio- and chemotherapies is not clear and a small number of treatment attempts with imatinib have been made in cases of CD117 positivity or treatment attempts on an endocrine basis. This work provides an overview of the literature on epidemiology, imaging and histopathological diagnostic features as well as therapeutic options of this same tumour form.

 
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