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kleintier konkret 2018; 21(06): 19-28
DOI: 10.1055/a-0668-0728
CVE-Fortbildung
Georg Thieme Verlag KG Stuttgart · New York

Insulintherapie bei der Katze – Tipps für die richtige Insulindosis

Katarina Hazuchova
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Publication Date:
21 December 2018 (online)

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Das Management des Diabetes mellitus ist komplex und bedarf einer engen Zusammenarbeit zwischen Tierarzt und Tierbesitzer. Die Insulintherapie stellt die Grundlage der Diabetesbehandlung bei der Katze dar. Wenn möglich, sollte die Insulintherapie durch die Fütterung einer kohlenhydratarmen, proteinreichen Diät unterstützt werden.
 

  • Literatur

  • 1 Rudloff E. Diabetic ketoacidosis in the cat: Recognition and essential treatment. J Feline Med Surg 2017; 19 (11) 1167-1174
    CrossrefPubMedGoogle Scholar
  • 2 Sparkes AH, Cannon M, Church D. et al. ISFM consensus guidelines on the practical management of diabetes mellitus in cats. J Feline Med Surg 2015; 17 (03) 235-250
    CrossrefPubMedGoogle Scholar
  • 3 Behrend E, Holford A, Lathan P. et al. 2018 AAHA diabetes management guidelines for dogs and cats. J Am Anim Hosp Assoc 2018; 54 (01) 1-21
    CrossrefPubMedGoogle Scholar
  • 4 Roomp K, Rand J. Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine. J Feline Med Surg 2009; 11 (08) 668-682
    CrossrefPubMedGoogle Scholar
  • 5 Roomp K, Rand J. Evaluation of detemir in diabetic cats managed with a protocol for intensive blood glucose control. J Feline Med Surg 2012; 14 (08) 566-572
    CrossrefPubMedGoogle Scholar
  • 6 Marshall RD, Rand JS, Morton JM. Treatment of newly diagnosed diabetic cats with glargine insulin improves glycaemic control and results in higher probability of remission than protamine zinc and lente insulins. J Feline Med Surg 2009; 11 (08) 683-691
    CrossrefPubMedGoogle Scholar
  • 7 Gostelow R, Scudder C, Hazuchova K. et al. One-year prospective randomized trial comparing efficacy of glargine and protamine zinc insulin in diabetic cats. 2017 ACVIM Forum Research Abstract Program. J Vet Intern Med 2017; 31 (04) 1273
    Google Scholar
  • 8 Martin GJ, Rand JS. Pharmacology of a 40 IU/ml porcine lente insulin preparation in diabetic cats: findings during the first week and after 5 or 9 weeks of therapy. J Feline Med Surg 2001; 3 (01) 23-30
    CrossrefPubMedGoogle Scholar
  • 9 Marshall RD, Rand JS, Morton JM. Glargine and protamine zinc insulin have a longer duration of action and result in lower mean daily glucose concentrations than lente insulin in healthy cats. J Vet Pharmacol Ther 2018; 31 (03) 205-212
    Google Scholar
  • 10 Marshall RD, Rand JS, Morton JM. Insulin glargine has a long duration of effect following administration either once daily or twice daily in divided doses in healthy cats. J Feline Med Surg 2008; 10 (05) 488-494
    CrossrefPubMedGoogle Scholar
  • 11 Gilor C, Ridge TK, Attermeier KJ. et al. Pharmacodynamics of insulin detemir and insulin glargine assessed by an isoglycemic clamp method in healthy cats. J Vet Intern Med 2010; 24: 870-874
    CrossrefPubMedGoogle Scholar
  • 12 Alt N, Kley S, Haessig M. et al. Day-to-day variability of blood glucose concentration curves generated at home in cats with diabetes mellitus. J Am Vet Med Assoc 2007; 230 (07) 1011-1017
    CrossrefPubMedGoogle Scholar
  • 13 Hazuchova K, Gostelow R, Scudder C. et al. Acceptance of home blood glucose monitoring by owners of recently diagnosed diabetic cats and impact on quality of life changes in cat and owner. J Feline Med Surg 2018; 20 (08) 711-720
    CrossrefPubMedGoogle Scholar
  • 14 Reusch C. Feline diabetes mellitus. In: Feldman EC, Nelson RW, Reusch C, Scott-Moncroie EB. eds. Canine and Feline Endocrinology. 4th ed. St. Louis, Missouri: Elsevier; 2014: 258-314
    Google Scholar
  • 15 Gostelow R, Hazuchova K, Scudder C. et al. Prospective evaluation of a protocol for transitioning porcine lente insulin-treated diabetic cats to human recombinant protamine zinc insulin. J Feline Med Surg 2017; 20 (02) 114-121
    PubMedGoogle Scholar
  • 16 Zini E, Osto M, Franchini M. et al. Hyperglycaemia but not hyperlipidaemia causes beta cell dysfunction and beta cell loss in the domestic cat. Diabetologia 2009; 52: 336-346
    CrossrefPubMedGoogle Scholar
  • 17 Gostelow R, Forcada Y, Graves T. et al. Systematic review of feline diabetic remission: separating fact from opinion. Vet J 2014; 202 (02) 208-221
    CrossrefPubMedGoogle Scholar
  • 18 Gostelow R. Uncovering the recipe for diabetic remission in the cat [PhD thesis]. Royal Veterinary College; 2016
    PubMedGoogle Scholar
  • 19 Viebrock KA, Dennis J. Hypoglycemic episodes in cats with diabetes mellitus: 30 cases (2013–2015). J Feline Med Surg 2018; 20 (06) 563-570
    CrossrefPubMedGoogle Scholar
  • 20 Roomp K, Rand J. Rebound hyperglycaemia in diabetic cats. J Feline Med Surg 2016; 18 (08) 587-596
    CrossrefPubMedGoogle Scholar
  • 21 Zini E, Salesov E, Dupont P. et al. Glucose concentrations after insulin-induced hypoglycemia and glycemic variability in healthy and diabetic cats. J Vet Intern Med 2018; 32 (03) 978-985
    CrossrefPubMedGoogle Scholar
  • 22 Hoenig M, Reusch C, Peterson ME. Beta cell and insulin antibodies in treated and untreated diabetic cats. Vet Immunol Immunopathol 2000; 77 (1 – 2): 93-102
    CrossrefPubMedGoogle Scholar
  • 23 Riederer A, Zini E, Salesov E. et al. Effect of the glucagon-like peptide-1 analogue exenatide extended release in cats with newly diagnosed diabetes mellitus. J Vet Intern Med 2016; 30 (01) 92-100
    CrossrefPubMedGoogle Scholar
  • 24 Nelson RW, Feldman EC, Ford SL. et al. Effect of an orally administered sulfonylurea, glipizide, for treatment of diabetes mellitus in cats. J Am Vet Med Assoc 1993; 203 (06) 821-827
    PubMedGoogle Scholar
  • 25 Nelson R, Spann D, Elliott D. et al. Evaluation of the oral antihyperglycemic drug metformin in normal and diabetic cats. J Vet Intern Med 2004; 18 (01) 18-24
    CrossrefPubMedGoogle Scholar